Rotational Thromboelastometry predicts care level in COVID-19
Rotational Thromboelastometry predicerar vårdnivå vid COVID-19
The objective of the study was to test whether Rotational Thromboelastometry (ROTEM) indicate hypercoagulopathy at hospitalization of COVID-19 patients, and whether patients with severe disease have a more pronounced hypercoagulopathy compared with less severely ill patients.
The study was designed as a prospective observational study where COVID-19 positive patients over 18 years admitted to Capio St Göran’s Hospital in Stockholm, Sweden, were eligible for inclusion. Patients were divided into two groups depending on care level: 1) regular wards (40 patients) or 2) wards with specialized ventilation support (20 patients). ROTEM and other coagulation tests (see table for a list and explanation of variables) was taken after admission and the data were compared with ROTEM in healthy controls.
Conclusion
ROTEM variables (EXTEM-MCF, FIBTEM-MCF, EXTEM-CT, EXTEM-CFT) were significantly different in COVID-19 patients early after admission compared with healthy controls. This pattern was more pronounced in patients with increased disease severity, suggesting that ROTEM-analysis could be a potentially useful predictor of thromboembolic complications and mortality in these patients.
For details, see publication at: https://doi.org/10.1007/s11239-020-02312-3
Syftet med studien var att testa om Rotational Thromboelastometry (ROTEM) indikerar att patienter med COVID-19 är benägna att bilda blodproppar. Även om provet skiljer sig åt beroende på om patienter på vanlig vårdavdelning testas jämfört med patienter på mer avancerade vårdavdelningar.
Se utförligare beskrivning i den engelska versionen av katalogposten.
För detaljer se artikeln: https://doi.org/10.1007/s11239-020-02312-3
2023-08-31T10:58:38.858415Z
2020-08-24T05:49:18.338287Z
Lou Almskog
Anna Ågren
Jonas Svensson
Jonas Svensson
Anesthesiology and Intensive Care
Anestesi och intensivvård
Hematology
Hematologi
Clinical Medicine
Klinisk medicin
Medical and Health Sciences
Medicin och hälsovetenskap
Thrombosis
Trombos
Embolism and Thrombosis
Emboli och trombos
Vascular Diseases
Kärlsjukdomar
Cardiovascular Diseases
Kardiovaskulära sjukdomar
ROTEM
ROTEM
COVID-19
COVID-19
2020-05-08
2020-05-31
Karolinska Institutet
Karolinska Institutet