A landscape of X-inactivation during human T-cell development in the thymus
SND-ID: 2022-112-1. Version: 1. DOI: https://doi.org/10.5878/frw5-wd59
- EPIC_methylation_meta.tsv (3 KB)
- Patient characteristics meta.tsv (369 bytes)
- RNAseq_normal_karyotype_meta.tsv (5.01 KB)
- RNAseq_turner_thymocyte_meta.tsv (5.38 KB)
- WES_STANDARD_meta.tsv (8.12 KB)
- WES_UTR_meta.tsv (1.44 KB)
Olov Ekwall - University of Gothenburg, Institute of Clinical Sciences, Department of Pediatrics
University of Gothenburg - Institute of Clinical Sciences
The dataset contains data from the manuscript "A landscape of X-inactivation during human T-cell development in the thymus" by Gylemo et al, and consists of results from RNA sequencing (fastq.gz), analysis of DNA methylation (Grn.idat) and whole exome DNA sequencing (fastq.gz) of six developmental stages of thymocytes from seven individuals.
The data is described on individual and cell-type level in the tab-separated metadata files (.tsv).
MD5 checksums for each file are included.
Data contains personal data
Sensitive personal data
Type of personal data
Human data. The data is pseudonymized and contains ID-numbers that can be coupled to individuals through a code-key.
Code key exists
Unit of analysis
Isolated thymocytes from seven persons were studied, three boys and four girls, all under 3 yrs that underwent cardiac surgery for correction of congenital heart defects.
Biobank is connected to the study
The study has collected samples/material which are stored in a scientific collection or biobank
Scientific collection or biobank name: Biobank Väst 890
Type(s) of sample: Isolerade thymocyter
This study has used existing samples from a scientific collection or biobank
Number of individuals/objects
Geographic location: Sweden
Institute of Clinical Sciences
Other research principals
- Funding agency: The ALF agreement: The Swedish state under the ALF agreement between the Swedish government and the county councils
- Funding agency's reference number: ALFGBG-965795
- Project name on the application: Kliniska och experimentella studier av toleransmekanismer i thymus
Gothenburg - Ref. 217-12
Project title: Studies of central tolerance induction in human thymus
Björn Gylemo, Antonio Lentini, Christina Lundqvist, Maike Bensberg, Alessandro Camponeschi, Dora Goldman, Aida Selimović, Olov Ekwall, Colm E. Nestor. (2022). A landscape of X-inactivation during human T-cell development [submitted manuscript].
If you have published anything based on these data, please notify us with a reference to your publication(s). If you are responsible for the catalogue entry, you can update the metadata/data description in DORIS.