The Swedish Mammography Cohort (SMC) 1987

SND-ID: ext0018-1.

Is part of collection at SND: Swedish Cohort Consortium (Cohorts.se), SIMPLER - Swedish Infrastructure for Medical Population-Based Life-Course and Environmental Research, NEAR - National E-Infrastructure for Aging Research in Sweden

Citation

Creator/Principal investigator(s)

Karl Michaëlsson - Uppsala University, Department of Surgical Sciences orcid

Research principal

Uppsala University - Department of Surgical Science rorId

Description

The Swedish Mammography Cohort (SMC) is a large population-based cohort of over 60,000 women in the counties of Uppsala and Västmanland. All women born 1914-1948 who were residing in Västmanland and Uppsala County and in the years 1987-1990 received an invitation to participate in a mammography screening programme were asked to answer a questionnaire about diet and lifestyle. Approximately 66,000 women answered the questionnaire. In the autumn 1997, a second survey was sent to these women to update the information about their eating habits. Additional follow-ups were done 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., breast, colorectal, endometrium, ovary, and renal cell cancer), myocardial infarction, stroke, osteoporosis, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done.

The questionnaires used in the

... Show more..
The Swedish Mammography Cohort (SMC) is a large population-based cohort of over 60,000 women in the counties of Uppsala and Västmanland. All women born 1914-1948 who were residing in Västmanland and Uppsala County and in the years 1987-1990 received an invitation to participate in a mammography screening programme were asked to answer a questionnaire about diet and lifestyle. Approximately 66,000 women answered the questionnaire. In the autumn 1997, a second survey was sent to these women to update the information about their eating habits. Additional follow-ups were done 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., breast, colorectal, endometrium, ovary, and renal cell cancer), myocardial infarction, stroke, osteoporosis, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done.

The questionnaires used in the Swedish Mammography Cohort are the same as the ones that have been used in the Cohort of Swedish Men (COSM). For updated information on questionnaires and variable lists please visit https://www.simpler4health.se/researchers/.

Purpose:

The general aim of the Swedish Mammography Cohort (SMC) is to assess relationships between a number of modifiable factors (diet, vitamin supplement use, physical activity, smoking, alcohol, body weight, other anthropometric measures etc.) and the occurrence of several major chronic diseases.

For more detailed information please visit the SIMPLER website, https://www.simpler4health.se/researchers/cohorts/.

For restrictions in data use see https://www.simpler4health.se/researchers/rules-and-guidelines/ and https://www.simpler4health.se/researchers/publication-policy/.

Women born between 1914 and 1948, and living in Västmanland county between 1987 and 1989 or living in Uppsala County between 1988 and 1990, received an invitation by mail to participate in a mammography screening program, in total 90,303 women. The invitation included a six-page questionnaire that sought information on diet and alcohol intake (67-item food frequency questionnaire), parity, age at first childbirth, family history of breast cancer, weight, height, education level, and marital status. The questionnaire can be found at https://www.simpler4health.se/researchers/questionnaires/. Show less..

Data contains personal data

Yes

Sensitive personal data

Yes

Type of personal data

health data

Code key exists

Yes

Language

Method and outcome

Population

Women born 1914-1948 living in Västmanland or Uppsala County during 1987-1990.

Study design

Observational study

Cohort study

Description of study design

Longitudinal cohort study

Sampling procedure

Total universe/Complete enumeration
From 1987 to 1990, all women who lived in the Uppsala County of central Sweden and were born between 1914-1948 and all women who lived in the adjacent Västmanland County and were born between 1917-1948 received an invitation by mail to participate in a mammography screening program. Included in the mail was also an invitation to participate in this research study and a questionnaire to be answered and returned. Follow-ups have been performed approximately every tenth year starting in 1997. At next follow-up, 2008/2009, the questionnaire was extended and separated into two questionnaires. An additional follow-up was done during 2019.

Time period(s) investigated

1987 – Ongoing

Biobank is connected to the study

The study has collected samples/material which are stored in a scientific collection or biobank

Scientific collection or biobank name: Uppsala biobank/SIMPLER

Type(s) of sample: DNA

Response rate/participation rate

74% / 90 303 women received the invitation, 66 651 answered the questionnaire and 61 433 participants remained after exclusions (wrong or missing personal number, cancer diagnosis etc.).

Data format / data structure

Data collection
  • Mode of collection: Self-administered questionnaire
  • Description of the mode of collection: Specific date for collection.
  • Time period(s) for data collection: 1987 – 1990
  • Source of the data: Population group
Geographic coverage

Geographic spread

Geographic location: Sweden

Geographic description: Uppsala and Västmanland counties, Sweden.

Lowest geographic unit

Municipality

Highest geographic unit

Country

Administrative information

Responsible department/unit

Department of Surgical Science

Ethics Review

Uppsala - Ref. 2018/262 och 2018/263

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Cancer and oncology (Standard för svensk indelning av forskningsämnen 2011)

Endocrinology and diabetes (Standard för svensk indelning av forskningsämnen 2011)

Cardiac and cardiovascular systems (Standard för svensk indelning av forskningsämnen 2011)

Orthopaedics (Standard för svensk indelning av forskningsämnen 2011)

Geriatrics (Standard för svensk indelning av forskningsämnen 2011)

General practice (Standard för svensk indelning av forskningsämnen 2011)

Public health, global health, social medicine and epidemiology (Standard för svensk indelning av forskningsämnen 2011)

Nutrition and dietetics (Standard för svensk indelning av forskningsämnen 2011)

Publications

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.
DOI: https://doi.org/10.13172/2053-079X-1-2-943

Link to publication list:

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