The European Dermato-Epidemiology Network (EDEN) Fragrance Study - EDEN-the Swedish part

SND-ID: ext0151-1.

Is part of collection at SND: Scania Metadatabase for Epidemiology (SME)

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Creator/Principal investigator(s)

Åke Svensson - Region Skåne, Dermatology, Malmö

Ewa Wallin - Region Skåne, Dermatology, Malmö

Research principal

Region Skåne


Contact allergy to fragrances appears to be increasing and data on allergy in the general population are limited. The EDEN cohort is a multinational study that involves several areas in five European countries (Sweden, Italy, Germany, The Netherlands and Portugal). The study was conducted during August 2008 to October 2011.

In total 12 000 individuals from these five countries was interviewed and about 3000 of these also underwent a patch test for different fragrance allergens. From Sweden 2069 individuals participated. The questionnaire contained questions concerning occupation, smoking, anthropometric data, previous experience with skin rash, and any history of reactions to products that may contain the sensitizer and/or a history of avoidance of the same products (e.g. skin lotions, deodorants, make-up and laundry detergent).


To determine the prevalence and severity of contact allergy to fragrances and other sensitizers in the general population in Europe

Participants from Sweden were 2069 individuals.
Method and outcome

Unit of analysis


More than 2,000 individuals living in Malmö.

Time Method

Sampling procedure

Time period(s) investigated

2008-08 – 2011-10

Number of individuals/objects


Data format / data structure

Data collection

Data collection 1

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2008-08 – 2011-10
  • Source of the data: Population group

Data collection 2

  • Mode of collection: Face-to-face interview
  • Time period(s) for data collection: 2008-08 – 2011-10
  • Source of the data: Population group
Geographic coverage

Geographic spread

Geographic description: Malmö

Administrative information

Ethics Review

Lund - Ref. 351/2006 komplettering 2008/96

Topic and keywords

Research area

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Other medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Health (CESSDA Topic Classification)


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Rossi M, Coenraads PJ, Diepgen T, Svensson Å, Elsner P, Gonçalo M, Bruze M, Naldi L. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: the European Dermato-Epidemiology Network Fragrance Study. Dermatology. 2010;221(3):267-75. doi: 10.1159/000319757.

Naldi L, Cazzaniga S, Goncalo M, Diepgen T, Bruze M, Elsner P, Coenraads PJ, Svensson A, Bertuccio P, Ofenloch R, EDEN Fragrance Study Group. Prevalence of self-reported skin complaints and avoidance of common daily life consumer products in selected European Regions. JAMA Dermatol 2014;150:154-63. oi: 10.1001/jamadermatol.2013.7932.
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