• Functional development in children and youth with cerebral palsy in Uganda

AIM To follow the functional development of a population-based cohort of children and youth (C&Y) with cerebral palsy (CP) in rural Uganda and compare their development with developmental trajectories from high-income co...

• A DNA-nanoassembly-based approach to map membrane protein nanoenvironments

Most proteins at the plasma membrane are not uniformly distributed but localize to dynamic domains of nanoscale dimensions. To investigate their functional relevance, there is a need for methods that enable comprehensive...

• Whole-genome sequencing of follicular thyroid carcinomas reveal recurrent mutations in microRNA processing subunit DGCR8

Background The genomic and transcriptomic landscape of widely invasive follicular thyroid carcinomas (wiFTCs) is poorly characterized, and a large subset of these tumours lack information on credible genetic driver event...

• Small non-coding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology

To improve our understanding of MS pathology and heterogeneity and provide new strategies for biomarkers and treatments development we carried out a genome-wide small non-coding RNA analysis. The analysis was performed i...

• Excessive premature mortality among children with cerebral palsy in rural Uganda: a longitudinal, population-based study

Background Studies from high-income countries reported reduced life expectancy in children with cerebral palsy (CP), while no population-based study has evaluated mortality of children with CP in sub-Saharan Africa. This...

• Rotational Thromboelastometry predicts care level in COVID-19

The objective of the study was to test whether Rotational Thromboelastometry (ROTEM) indicate hypercoagulopathy at hospitalization of COVID-19 patients, and whether patients with severe disease have a more pronounced hyp...

• A multimodal brain imaging dataset on sleep deprivation in young and old humans: The Sleepy Brain Study 1

The Stockholm Sleepy Brain Study I is a functional brain imaging study of 48 younger (20-30 years) and 36 older (65-75 years) healthy participants, with magnetic resonance imaging after normal sleep and partial sleep dep...

• Effects of normocaloric vs. hypocaloric enteral nutrition on whole-body protein turnover in critically ill patients

Enteral nutrition (EN) is a ubiquitous intervention in ICU patients but there is uncertainty regarding the optimal dose, timing and importance for patient-centered outcomes during critical illness. Our research group has...

• Modeling the Transport of Nuclear Proteins Along Single Skeletal Muscle Cells

The purpose of this study was to define the factors that control the distribution of nuclear proteins in multinucleated skeletal muscle cells (myotubes). Nuclear-targeted red fluorescent proteins of different molecular w...

• High-risk human papillomavirus status and prognosis in invasive cervical cancer: a nationwide cohort study

High-risk human papillomavirus (hrHPV) infection is established as the major cause of invasive cervical cancer (ICC). However, whether hrHPV status in the tumor is associated with subsequent prognosis of ICC is controver...