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Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin)

SND-ID: 2021-195

This study is part of the collection NEAR - National E-Infrastructure for Aging Research in Sweden

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Description

The OCTO-Twin Study aims to investigate the etiology of individual differences among twin-pairs age 80 and older, on a range of domains including health and functional capacity, cognitive functioning, psychological well-being, personality and personal control. In the study, twin pairs were withdrawn from the Swedish Twin Registry. At the first wave, the twins had to be born 1913 or earlier and both partners in the pair had to accept participation. At baseline in 1991-94, 351 twin pairs (149 monozygotic and 202 like-sex dizygotic pairs) were investigated (mean age: 83.6 years and 67% were female). The two-year longitudinal follow-ups were conducted on all twins who were alive and agreed to participate. Data have been collected at five waves over a total of eight years.

Language

English

Swedish

Research principal, contributors, and funding

Research principal

University of Gothenburg

Responsible department/unit

Department of Psychology

Protection and ethical review

Data contains personal data

Yes

Sensitive personal data

Yes

Type of personal data

Pseudonymised data related to mental and physical health, as well as socio-demographics and social relationships

Code key exists

Yes

Ethics Review

Other - Ref. S-005011-50

Approval of Assurance to Comply with 45 CFR 46. Public Health Service, National Institutes of Health, USA. Office for Protection from Research Risks. July 20, 1999. Accepted by the ethical committee of the Karolinska Institute

Method and time period

Unit of analysis

Population

Twin pairs from the Swedish Twin Registry who were born 1913 or earlier and were at the age of 80 years at baseline.

Time Method

Study design

Observational study

Cohort study

Cohort study: Prospective

Description of study design

Longitudinal study

Time period(s) investigated

1991 – 2002

Geographic coverage

Geographic spread

Geographic location: Sweden

Topic and keywords

Research area

Gerontology, specialising in Medical and Health Sciences, Psychology (The Swedish standard of fields of research 2011)

Keywords

activities of daily living, aged, 80 and over, epidemiologic studies, dementia, life style, geriatrics, memory, longitudinal studies, neuropsychological tests, socioeconomic factors, body mass index, genes, cognition, environment, depression, personality, mental health, registries, diabetes mellitus, type 2, heredity, quality of life, twin study, aging, apolipoproteins e, memory disorders, nerve degeneration, wechsler scales, degenerative disease of nervous system unspecified, mental status and dementia tests, wechsler memory scale, apoe genotype, functional status, memory function, social interaction, near - national e-infrastructure for aging research, functional ability, social life

Publications

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Cadar, D., Piccinin, A. M., Hofer, S. M., Johansson, B., & Muniz-Terrera, G. (2016). Education, occupational class, and cognitive decline in preclinical dementia. In GeroPsych: The Journal of Gerontopsychology and Geriatric Psychiatry (Vol. 29, Issue 1, pp. 5–15).
DOI: https://doi.org/10.1024/1662-9647/a000138

Berg, A. I. (2008). Life satisfaction in late life: Markers and predictors of level and change among 80+ year olds [Doctoral thesis]. Department of Psychology, University of Gothenburg.
Handle: http://hdl.handle.net/2077/17873
ISBN: 9789162876012

Wikby, A., Ferguson, G. F., Forsey, R., Thompson, J., Strindhall, J., Löfgren, S., Nilsson, B.-O., Ernerudh, J., Pawelec, G., & Johansson, B. (2005). An immune risk phenotype, cognitive impairment and survival in very late life: The impact of alostatic load in Swedish Octo- and Nongenarian humans. In The Journals of Gerontology: Series A, Volume 60, Issue 5 (pp. 556–565).
DOI: https://doi.org/10.1093/gerona/60.5.556

McClearn, G. E., Johansson, B., Berg, S., Pedersen, N. L., Ahern, F., Petrill, S. A., et al. (1997). Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science, 276, 1560-1563.
DOI: https://doi.org/10.1126/science.276.5318.1560

Hassing, L. (2020). Gender Differences in the Association Between Leisure Activity in Adulthood and Cognitive Function in Old Age: A Prospective Longitudinal Population-Based Study. In The journals of gerontology. Series B, Psychological sciences and social sciences (Vol. 75, Issue 1, pp. 11-20).
DOI: https://doi.org/10.1093/geronb/gbx170

Johansson, B., Johansson, B., McClearn, G., & Pedersen, N. (2003). Health, biobehavioral functioning, and personality in the oldest-old: The Swedish OCTO-Twin Study. Presented at the 56th Annual Scientific Meeting of the Gerontological Society of America, San Diego. In GERONTOLOGIST (Vol. 43, Special Issue 1, p. 507).

Yoneda, T., Rush, J., Berg, A. I., Johansson, B., & Piccinin, A. (2017). Trajectories of Personality Traits Preceding Dementia Diagnosis. In The journals of gerontology. Series B, Psychological sciences and social sciences (Vol. 72, Issue 6, pp. 922–931).
DOI: https://doi.org/10.1093/geronb/gbw006

Hofer, S. M., Johansson, B., Berg, S., Pedersen, N. L., & McClearn, G. E. (2001). Changes in Cognitive Functioning in the Oldest-Old Twins : The Octo-Twin Study. Presented at the 54th Annual Scientific Meeting of the Gerontological Society of America, Chicago. In GERONTOLOGIST (Vol. 41, Special Issue 1, p. ?).

Nilsson, B.-O., Ernerudh, J., Johansson, B., Evring, P.-E., Löfgren, S., Ferguson, F. G., & Wikby, A. (2003). Morbidity does not influence the T-cell immune risk phenotype in the elderly : Findings in the Swedish NONA Immune Study using sample selection protocols. In Mechanisms of Ageing and Development (Vol. 124, Issue 4, pp. 469–476). https://doi.org/10.1016/S0047-6374(03)00024-1
DOI: https://doi.org/10.1016/S0047-6374(03)00024-1
URN: urn:nbn:se:liu:diva-26438

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Dataset 1
Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1

Description

The OCTO-Twin Study aims to investigate the etiology of individual differences among twin-pairs age 80 and older, on a range of domains including health and functional capacity, cognitive functioning, psychological well-being, personality and personal control. In the study, twin pairs were withdrawn from the Swedish Twin Registry. At the first wave, the twins had to be born 1913 or earlier and both partners in the pair had to accept participation. At baseline in 1991-94, 351 twin pairs (149 mono

... Show more..

Data format / data structure

Numeric

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Time period(s) investigated

1991 – 1994

Data collection

  • Mode of collection: Measurements and tests
  • Description of the mode of collection: The participants were examined in their home settings by registered nurses. The participants also answered a number of self-administered surveys.
  • Time period(s) for data collection: 1991-02–1994-03
  • Data collector: University of Gothenburg
  • Sample size: 702
  • Source of the data: Registers/Records/Accounts: Medical/Clinical

Variables

1062

Number of individuals/objects

702

URI

https://neardb.near-aging.se/dataset/octo_wave1

Dataset 2
Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 2

Description

In wave 2, 235 twin pairs participated, with a total of 568 individuals.
Refer to the description of wave 1/the base line and the individual datasets in the NEAR portal for more details on variable groups and individual variables.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Data collection

  • Mode of collection: Measurements and tests
  • Description of the mode of collection: The participants were examined in their home settings by registered nurses. The participants also answered a number of self-administered surveys.
  • Time period(s) for data collection: 1993-05–1996-05
  • Data collector: University of Gothenburg
  • Sample size: 568
  • Source of the data: Registers/Records/Accounts: Medical/Clinical

Variables

1001

Number of individuals/objects

568

URI

https://neardb.near-aging.se/dataset/octo_wave2

Dataset 3
Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 3

Description

In wave 3, 144 twin pairs participated, with a total of 430 individuals.
Refer to the description of wave 1/the base line and the individual datasets in the NEAR portal for more details on variable groups and individual variables.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Data collection

  • Mode of collection: Measurements and tests
  • Description of the mode of collection: The participants were examined in their home settings by registered nurses. The participants also answered a number of self-administered surveys.
  • Time period(s) for data collection: 1995-04–1998-05
  • Data collector: University of Gothenburg
  • Sample size: 430
  • Source of the data: Registers/Records/Accounts: Medical/Clinical

Variables

998

Number of individuals/objects

430

URI

https://neardb.near-aging.se/dataset/octo_wave3

Dataset 4
Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 4

Description

In wave 4, 84 twin pairs participated, with a total of 315 individuals.
Refer to the description of wave 1/the base line and the individual datasets in the NEAR portal for more details on variable groups and individual variables.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Data collection

  • Mode of collection: Measurements and tests
  • Description of the mode of collection: The participants were examined in their home settings by registered nurses. The participants also answered a number of self-administered surveys.
  • Time period(s) for data collection: 1997-04–2000-05
  • Data collector: University of Gothenburg
  • Sample size: 315
  • Source of the data: Registers/Records/Accounts: Medical/Clinical

Variables

998

Number of individuals/objects

315

URI

https://neardb.near-aging.se/dataset/octo_wave4

Dataset 5
Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 5

Description

In wave 5, 43 twin pairs participated, with a total of 222 individuals.
Refer to the description of wave 1/the base line and the individual datasets in the NEAR portal for more details on variable groups and individual variables.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Linda Hassing - University of Gothenburg, Department of Psychology orcid

Time period(s) investigated

Data collection

  • Mode of collection: Measurements and tests
  • Description of the mode of collection: The participants were examined in their home settings by registered nurses. The participants also answered a number of self-administered surveys.
  • Time period(s) for data collection: 1999-12–2002-03
  • Data collector: University of Gothenburg
  • Sample size: 222
  • Source of the data: Registers/Records/Accounts: Medical/Clinical

Variables

927

Number of individuals/objects

222

URI

https://neardb.near-aging.se/dataset/octo_wave5

Contact for questions about the data

Is part of collection at SND

NEAR - National E-Infrastructure for Aging Research in Sweden

Published: 2022-05-13
Last updated: 2023-04-03