10.5878/txww-hg72
Kakooza-Mwesige, Angelina
Angelina
Kakooza-Mwesige
0000-0002-1189-3671
Pediatrics and Child Health, Makerere University Kampala Uganda
Functional development in children and youth with cerebral palsy in Uganda
Functional development in children and youth with cerebral palsy in Uganda
Functional development of Ugandan children/youth with CP
Karolinska Institutet
2021
Uganda
Uganda
Africa, Eastern
Östafrika
Africa South of the Sahara
Afrika söder om Sahara
Africa
Afrika
Geographic Locations
Geografiska namn
Africa
Afrika
Functional development
Funktionell utveckling
cerebral palsy
cerebral pares
Medical and Health Sciences
Medicin och hälsovetenskap
Neurology
Neurologi
Pediatrics
Pediatrik
Public Health, Global Health, Social Medicine and Epidemiology
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Physiotherapy
Sjukgymnastik
Clinical Medicine
Klinisk medicin
Health Sciences
Hälsovetenskap
Pediatrics and Child Health, Makerere University
https://ror.org/03dmz0111
2021-08-19
2015-04/2019-12
2015-04/2019-12
eng
10.5878/cq2r-4248
10.1016/S2214-109X(17)30374-1
10.1111/dmcn.14996
35 variables
81 cases
1
AIM
To follow the functional development of a population-based cohort of children and youth (C&Y) with cerebral palsy (CP) in rural Uganda and compare their development with developmental trajectories from high-income countries (HIC).
METHODS
Eighty-one C&Y aged 2–17 years with CP were assessed 2015 and 2019 using Gross Motor Function Measure-66 items (GMFM-66), Pediatric Evaluation of Disability Inventory, Ugandan version (PEDI-UG), and functional classification systems. We calculated scaled scores (actual scores) and reference scores (amount of deviation from HIC developmental trajectories). Wilcoxon signed rank test was used for statistical analyses.
RESULTS
C&Y with CP in Uganda exhibited no differences in scaled scores between the first and second assessments for GMFM-66 and PEDI-UG mobility skills, while they exhibited increased PEDI-UG self-care skills (p<0.001). Reference scores were more negative at the second assessment than at the first assessment for GMFM-66 (p=0.002) and PEDI-UG mobility (p=0.036) but not for PEDI-UG self-care. The increased difference in reference scores over the 4 years were primarily driven by younger children (2–5 years) and C&Y with milder impairments.
INTERPRETATION
The increased difference in reference scores between assessments suggests that C&Y with CP in Uganda develop motor skills at a lower rate than peers in HIC.
The dataset contains of the following files:
- Functional_development_in Uganda_dataset_Andrews_et_al.csv
- Variable_list_for_functional_development_in_Uganda_dataset_Andrews_et_al.pdf
Information about the tool Gross Motor Function Measure-66 (GMFM-66):
https://www.canchild.ca/en/resources/44-gross-motor-function-measure-gmfm
Syfte
Att följa den funktionella utvecklingen för en populationsbaserad kohort av barn och ungdomar med cerebral pares (CP) på landsbygden i Uganda, och jämföra deras utveckling med utvecklingskurvor från höginkomstländer.
Metod
81 barn och ungdomar mellan 2-17 år undersöktes 2015 och 2019 med Gross Motor Function Measure-66 (GMFM-66) Pediatric Evaluation of Disability Inventory, Ugandan version (PEDI-UG), och funktionella klassifikationssystem.
Datasetet består av följande filer:
- Functional_development_in Uganda_dataset_Andrews_et_al.csv
- Variable_list_for_functional_development_in_Uganda_dataset_Andrews_et_al.pdf
Information om verktyget Gross Motor Function Measure-66 (GMFM-66):
https://www.canchild.ca/en/resources/44-gross-motor-function-measure-gmfm
Uganda
Sub-Saharan Africa
Africa
Swedish Ressearch council
https://ror.org/03zttf063