The Swedish Mammography Cohort, SMC

Principal investigator(s):

Alicja Wolk - Karolinska Institute, Institute of Environmental Medicine

Abstract:

The Swedish Mammography Cohort (SMC) is a large population-based cohort of over 60,000 women in the counties of Uppsala and Västmanland which is performed by the National Institute of Environmental Medicine, Karolinska Institutet . The general aim is to assess relationships between a number of modifiable factors (diet, vitamin supplement use, physical activity, smoking, alcohol, body weight, other anthropometric measures etc.) and the occurrence of several major chronic diseases. All women born 1914-1948 who were residing in Västmanland and Uppsala County and in the years 1987-1990 received an invitation to participate in a mammography screening programme were asked to answer a questionnaire about diet and lifestyle. Approximately 66,000 women answered the questionnaire. In the autumn 1997, a second survey was sent to these women to update the information about their eating habits. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., breast, colon, rectum, endometrium, ovary, and renal cell cancer), myocardial infarction, stroke, osteoporos

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Contact:

Alicja Wolk

Identifiers:

SND-ID:

Principal investigator(s):

Alicja Wolk - Karolinska Institute, Institute of Environmental Medicine

Principal organisation:

Purpose:

The general aim of the Swedish Mammography Cohort (SMC) is to assess relationships between a number of modifiable factors (diet, vitamin supplement use, physical activity, smoking, alcohol, body weight, other anthropometric measures etc.) and the occurrence of several major chronic diseases.

Abstract:

The Swedish Mammography Cohort (SMC) is a large population-based cohort of over 60,000 women in the counties of Uppsala and Västmanland which is performed by the National Institute of Environmental Medicine, Karolinska Institutet . The general aim is to assess relationships between a number of modifiable factors (diet, vitamin supplement use, physical activity, smoking, alcohol, body weight, other anthropometric measures etc.) and the occurrence of several major chronic diseases. All women born 1914-1948 who were residing in Västmanland and Uppsala County and in the years 1987-1990 received an invitation to participate in a mammography screening programme were asked to answer a questionnaire about diet and lifestyle. Approximately 66,000 women answered the questionnaire. In the autumn 1997, a second survey was sent to these women to update the information about their eating habits. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., breast, colon, rectum, endometrium, ovary, and renal cell cancer), myocardial infarction, stroke, osteoporos

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Time period(s) investigated:

1987 — ongoing

Collection events:

1987 — 1990 (Self-administered questionnaire: paper)
1997 (Self-administered questionnaire: paper)
2008 (Self-administered questionnaire: paper)
2009 (Self-administered questionnaire: paper)

Lowest geographic unit:

County (NUTS3)

Unit of analysis:

Population:

Women born 1914-1948 living in Västmanland or Uppsala County during 1987-1990

Time Method/Study design:

Sampling procedure:

Total universe/Complete enumeration
From 1987 to 1990, all women who lived in the Uppsala County of central Sweden and were born between 1914-1948 and all women who lived in the adjacent Västmanland County and were born between 1917-1948 received an invitation by mail to participate in a mammography screening program. A total of 66,651 (74% of the source population) returned a completed questionnaire on diet, weight, height, parity, and education. In 1997, a follow-up questionnaire was sent to all cohort members who were still living in the study area. Further follow-up was made during 2008-2009. The 2009 questionnaire was sent only to those who answered 2008.

Publications

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Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.

Stackelberg O, Björck M, Larsson SC, Orsini N, Wolk A. Fruit and vegetable consumption with risk of abdominal aortic aneurysm. Circulation 128(8):795-802, 2013.

Wolk A, Larsson SC, Johansson JE, Ekman P. Long-term fatty fish consumption and renal cell carcinoma incidence in women. JAMA. 296(11):1371-6, 2006.

If you have published anything based on this study, please send a notification with a reference to your publication(s) to snd@snd.gu.se.

Dataset EXT 0018-001

The Swedish Mammography Cohort, SMC

Kind of data:

Collection events:

1987 - 1990 (Self-administered questionnaire: paper)

Number of individuals/objects:

61433

Response rate:

74%

Dataset EXT 0018-002

The Swedish Mammography Cohort, SMC 1997

Kind of data:

Collection events:

1997 (Self-administered questionnaire: paper)

Number of individuals/objects:

39227

Response rate:

70%

Dataset EXT 0018-003

The swedish mammography cohort, SMC 2008

Kind of data:

Collection events:

2008 (Self-administered questionnaire: paper)

Number of individuals/objects:

30621

Response rate:

63%

Dataset EXT 0018-004

The Swedish mammography cohort, SMC 2009

Kind of data:

Collection events:

2009 (Self-administered questionnaire: paper)

Number of individuals/objects:

25332

Response rate:

84%