Betula - aging, memory and dementia

Principal investigator(s):

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institute, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Abstract:

The Betula Project is a longitudinal study of aging, memory and dementia. Data was collected between 1988 - 2014. Then the study began with including 1000 randomly selected individs from the Umeå municipality in the age groups 20, 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 years. It was 100 in each age cohort, and the gender distribution was similar to the population with about as many men as women in the younger age groups, and about twice as many women as men in the age groups 70 and over. Five years later, wo more sample were included. The group has been monitored every five years: 1993, 1998, 2003, 2008 and 2013. For each sample, each participant completed a thorough physical examination with blood tests of a nurse and a careful examination of a memory tester. There are data collected from approximately 4,700 participants. On each occasion, data for about 2000 variables were collected for each participant, which includes data on demographics, health, illness, medication, social and cognitive factors. The Betula project has received funding for research infrastructures (large databases) f

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Contact:

Mikael Stiernstedt

Study number:

Principal investigator(s):

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institute, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Principal organisation:

Purpose:

Study how memory functions change during adult life, to identify risk factors for dementia and to identify early preclinical signs of dementia and determine the critical factors of successful aging.

Abstract:

The Betula Project is a longitudinal study of aging, memory and dementia. Data was collected between 1988 - 2014. Then the study began with including 1000 randomly selected individs from the Umeå municipality in the age groups 20, 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 years. It was 100 in each age cohort, and the gender distribution was similar to the population with about as many men as women in the younger age groups, and about twice as many women as men in the age groups 70 and over. Five years later, wo more sample were included. The group has been monitored every five years: 1993, 1998, 2003, 2008 and 2013. For each sample, each participant completed a thorough physical examination with blood tests of a nurse and a careful examination of a memory tester. There are data collected from approximately 4,700 participants. On each occasion, data for about 2000 variables were collected for each participant, which includes data on demographics, health, illness, medication, social and cognitive factors. The Betula project has received funding for research infrastructures (large databases) f

... more

Time period(s) investigated:

1988 — 2014

Collection events:

1988 — 1990 (Self-administered questionnaire)
1988 — 1990 (Physical measurements and tests)
1988 — 1990 (Psychological measurements and tests)
1993 — 1995 (Self-administered questionnaire)
1993 — 1995 (Physical measurements and tests)
1993 — 1995 (Psychological measurements and tests)
1998 — 2000 (Self-administered questionnaire)
1998 — 2000 (Physical measurements and tests)
1998 — 2000 (Psychological measurements and tests)
2003 — 2005 (Self-administered questionnaire)
2003 — 2005 (Physical measurements and tests)
2003 — 2005 (Psychological measurements and tests)
2008 — 2010 (Self-administered questionnaire)
2008 — 2010 (Physical measurements and tests)
2008 — 2010 (Psychological measurements and tests)
2013 — 2014 (Self-administered questionnaire)
2013 — 2014 (Physical measurements and tests)
2013 — 2014 (Psychological measurements and tests)

Geographic location:

Geographic description:

Umeå county

Unit of analysis:

Universe/Population:

Indivduals in agegroups between 25-80 living in Umeå county

Time Method/Study design:

Sampling procedure:

Probability: Stratified
1000 individuals in age groups 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 were randomly selected (sample 1, S1). There were 100 individuals i each age cohort, the gender distribution reflected the gender distribution in the population ie about as many men as women in the younger age groups and about twice as many women as men from age group 70 and above (test occasion 1, T1) In T2, five years later, two new samples were added to the group, S2 and S3, randomly selected från Umeå county.

Publications

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Nixon Andreasson, A., Szulkin, R., Undén, A.-L., von Essen, J., Nilsson, L.-G., & Lekander, M. (in press). Inflammation and positive affect related to subjective health: Women from the general population. Health Psychology.

Pickard B.S., Van Den Bossche M.J., Malloy M.P., Johnstone M., Lenaerts A.S., Nordin A., Goossens D., St Clair D., Muir W.J., Nilsson L.-G., Sabbe B., Adolfsson R., Blackwood D.H., & Del-Favero J. (in press). Multiplex amplicon quantification screening the ABCA13 gene for copy number variation in schizophrenia and bipolar disorder. Psychiatric Genetics. 2012 Mar 1. [Epub ahead of print]

Mousavi-Nasab, S.-M. H., Kormi-Nouri, R., Sundström, A., & Nilsson, L.-G. (2012) The effects of marital status on episodic and semantic memory in healthy middle-aged and old individuals. Scandinavian Journal of Psychology, 53, 1-8. Doi: 10.1111/j.1467-9450.2011.00926.x

Salami, A., Eriksson, J., Nyberg, L., & Nilsson, L.-G. (2012). Age-related white matter microsctructural differences are not major mediators of cognitive decline in aging. Biochemica et Biophysica Acta-Molecular Basis of Disease, 1822, 408-415. Doi: 10.1016/jbbadis.2011.09.001.

Wikgren, M., Karlsson, T., Nilbrink, T., Nordfjäll, K., Hultdin, J., Sleegers, K., Van Broeckhoven, C., Nyberg, L., Roos, G., Nilsson, L.-G., Adolfsson, R., & Norrback, K.-F. (2012). APOE e4 is associated with longer telomeres, and longer telomeres among e4 carriers predicts worse episodic memory. Neurobiology of Aging, 33, 335-344. Doi: 10.1016/j.neurobiolaging.2010.03.004.

Wikgren, M., Maripuu, M., Karlsson, T., Nordfjäll, K., Bergdahl, J., Hultdin, J., Del-Favero, J., Roos, G., Nilsson, L.-G., Adolfsson, R., & Norrback, K.-F. (2012). Short telomeres in depression and the general population are associated with hypocortisolemic state. Biological Psychiatry, 71, 294-300. Doi: 10.1016/j.biopsych.2011.09.015.

Ceulemans, S., De Zutter, S., Heyrman, L., Norrback, K.-F., Nordin, A., Nilsson, L.-G., Adolfsson, R., Del-Favero, J., & Claes, S. (2011). Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated Swedish population. Bipolar Disorders, 13, 614-623. Doi: 10.1111/j.1399-5618.2011.00960.x.

Hedner, M., Nilsson, L.-G., Olofsson, J.K., Bergman, O., Eriksson, E., Nyberg, L., & Larsson, M. (2011). Age-related olfactory decline is associated with the val66met polymorphism: Evidence from a population-based study. Frontiers of Cognitive Aging: Neoroscience. Doi: 10.3389/fnagi.2010.00024.

Kauppi, K., Nilsson, L.-G., Adolfsson, R., Eriksson, E., & Nyberg, L. (2011). KIBRA polymorphism is related to enhanced memory and elevated hippocampal processing. Journal of Neuroscience, 40, 14218-14222. Doi: 10.1523/jneurosci.3292-11.2011.

Kompus, K., Westerhausen, R., Nilsson, L.-G., Hugdahl, K., Jongstra, S., Berglund, A., Arver, S., & Savic, I. (2011). Deficits in inhibitory executive functions in Klinefelter (47, XXY) syndrome. Psychiatry Research, 189, 135-140. Doi: 10.1016/jpsychres.201102.028.

Lekander, M., von Essen, J., Schultzberg, M., Nixon Andreasson, A., Garlind, A., Hansson, L.-O., & Nilsson, L.-g. (2011). Cytokines and memory across the mature life span of women. Scandinavian Journal of Psychology, 52, 229-235. Doi: 10.1111/j.1467-9450.2010.00865.x.

Moens, L.N., De Rijk, P., Reumers, J., Van den Bossche, M.J.A., Glassee, W., De Zutter, S., Lenaerts, A.S., Nordin, A., Nilsson, L.-G., Castello, I.M., Norrback, K.F., Goossens, D., Van Steen, K., Adolfsson, R., & Del-Favero, J. (2011). Sequencing of DISC1 patheway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population. PlosONE, 6. Doi: 10.1371/journal.pone.0023450.

Nilsson, L.-G. (2011). Genetic and demographic factors related to successful aging. Frontiers in Human Neuroscience. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). Doi: 10.3389/conf.fnhum.2011.207.00593

Persson, J., Kalpouzos, G., Nilsson, L.-G., Ryberg, M., & Nyberg, L. (2011). Preserved hippocampus activation in normal aging as revealed by fMRI. Hippocampus, 21, 753-766. Doi: 10.1002/hipo.20794.

Rönnberg, J., Danielsson, H., Rudner, M., Arlinger, S., Sternäng, O., Wahlin, Å., & Nilsson, L.-G. (2011). Hearing loss is negatively related to episodic and semantic long-term memory but not to short-term memory. Journal of Speech, Language, and Hearing Research, 54, 705-726. Doi: 10.1044/1092-4388(2010/09-0088).

Sundström, A., Bergdahl, J., Nyberg, L., Bergdahl, M., & Nilsson, L.-G. (2011). Stressful negative life events and amalgam-related complaints. Community Dentistry and Oral Epidemiology, 39, 12-18. Doi: 10.1111/j.1600-0528.2010.00571.x

Vestergren, P., & Nilsson, L.-G. (2011). Perceived causes of everyday memory problems in a population-based sample aged 39-99. Applied Cognitive Psychology, 25, 641-646. Doi: 10.1002/acp.1734.

Vestergren, P., Rönnlund, M., Nyberg, L., & Nilsson, L.-G. (2011). Development of the Cognitive Dysfunction Questionnaire (CDQ) in a population based sample. Scandinavian Journal of Psychology, 52, 218-228. Doi: 10.1111/j.1467-9450.2010.00861.x.

Backeström, A., Eriksson, S., Nilsson, L.-G., Nyberg, L., Olsson, T., & Rolandsson, O. (2010). Glucose metabolism and cognitive dysfunction. Diabeologia, 53, 730.

Bergman, O., Westberg, L., Nilsson, L.-G., Adolfsson, R., & Eriksson, E. (2010). Preliminary evidence that polymorphisms in dopamine-related transcription factors LMX1A, LMX1B and PITX3 are associated with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34, 1094-1097.

Danielsson, H., Henry, L., Rönnberg, J., & Nilsson, L.-G. (2010). Executive functions in individuals with intellectual disability. Research in Developmental Disabilities, 31, 1299-1304.

Danielsson, H., Henry, L.A., Rönnberg, J., & Nilsson, L.-G. (2010). Selective problems in executive function in adults with ID: The Betula Database. Journal of Applied Research in Intellectual Disabilities, 23, 438-458.

Eriksson, D., Nilsson, L.-G., Rönnlund, M., & Sundström, A. (2010). Effects of perceived long-term stress on health and memory functioning. Abstracts of the Psychonomic Society, 15, 78-78.

de Frias, C.M., Marklund, P., Eriksson, E., Larsson, A., Öhman, L., Annerbrink, K., Bäckman, L., Nilsson, L.-G., & Nyberg, L. (2010). Influence of COMT gene polymorphism on fMRI-assessed sustained and transient activity during a working-memory task. Journal of Cognitive Neuroscience, 22, 1614-1622.

Malmberg, G., Nilsson, L.-G., & Weinehall, L. (2010). Longitudinal data for interdiscipinary aging research. Scandinavian Journal of Public Health, 38, 761-767.

Nilsson, L.-G. (2010). The Betula Study: Memory, ageing, health and dementia in Sweden. Public Service Review: European Union, 19, 130-131.

Nyberg, L., Salami, A., Andersson, M., Eriksson, J., Kalpouzos, G., Kauppi, K., Lind, J., Pudas, S., Persson, J., & Nilsson, L.-G. (2010) Longitudinal evidence for diminished frontal-cortex function in aging. PNAS, 107, 22682-22686. Doi: 10.1073/pnas.1012651108.

Olofsson, J.K., Nordin, S., Wiens, S., Hedner, M., Nilsson, L.-G., & Larssson, M. (2010). Odor identification impairment in carriers of ApoE-?4 is independent of dementia. Neurobiology of Aging, 31, 567-577.

Sternäng, O., Jonsson, B., Wahlin, Å., Nyberg, L., & Nilsson, L.-G (2010). Examination of the common cause account in a population-based longitudinal study with narrow age cohort design. Gerontology, 56, 553-563.

Sundström, A., Bergdahl, J., Nyberg, L., Bergdahl, M., & Nilsson, L.-G. (2010). Cognitive status in persons with Amalgam related complaints. Journal of Dental Research, 89, 1236-1240.

Thilers, P.P., MacDonald, S.W., Nilsson, l.-G., & Herlitz, A. (2010). Accelerated postmenopausal cognitive decline is restricted to women ith normal BMI: Longitudinal evidence from the Betula project. Psychoneuroendocrinology, 35, 516-524.

Alaerts, M., Ceulemans, S., Forero, D., Moens, L.N., De Zutter, S., Heyman, L., Lenaerts, A.S., Norrback, K.F., Goossens, D., De Rijk, P., Nilsson, L.-G., Adolfsson, R., & Del-Favero, J. (2009). Detailed analysis of the serotonin transporter gene (SLC6A4) shows no association with bipolar disorder in the Northern Swedish population. American Journal of Medical Genetics: Neuropsychiatric Genetics, 150B, 585-592.

Alaerts, M., Ceulemans, S., Forero, D., Moens, L.N., De Zutter, S., Heyman, L., Lenaerts, A.S., Norrback, K.F., De Rijk, P., Nilsson, L.-G., Goossens, D., Adolfsson, R., & Del-Favero, J. (2009). Support for NRG1 as a susceptibility factor for schizophrenia in a Northern Swedish isoated population. Archives of General Psychiatry, 66, 828-828

Ballesteros, S., Nilsson, L.-G., & Lamaire, P. (2009). Ageing, cognition and neuroscience: An introduction. European Journal of Cognitive Psychology, 21, 161-175.

Maitland, S.B., Nyberg, L., Bäckman, L., Nilsson, L.-G., & Adolfsson, R. (2009). The search for structure: The temperament character of the Temperament and Character Inventory. In C. Herzog (Ed.), Cognition and aging: Methodologies and applications. Washington, DC: American Psychological Association.

Maitland, S.B., Nyberg, L., Bäckman, L., Nilsson, L.-G., & Adolfsson, R. (2009). On the structure of personality: Are there separate temperament and character factors. Personality and Individual Differences, 47, 180-184.

Naghavi, H.R., Lind, J., Nilsson, L.-G., Adolfsson, R., & Nyberg, L. (2009). Personality traits predict response to novel and familiar stimuli in the hippocampal region. Psychiatry Research: Neuroimaging, 173, 94-99

Nilsson, L.-G., Sternäng, O., Rönnlund, M., & Nyberg, L. (2009). Challenging the notion of an early-onset of cognitive aging. Neurobiology of Aging, 30, 521-524.

Nyberg, L., Andersson, M., Forsgren, L., Jakobsson-Mo, S., Larsson, A., Marklund, P., Nilsson, L.-G., Riklund, K., & Bäckman, L- (2009). Striatal dopamine D2 binding is related to frontal BOLD response during updating of long-term memory representations. NeuroImage, 46, 1194-1199.

Olofsson, J., Rönnlund, M., Nordin, S., Nyberg, L., Nilsson, L.-G., & Larsson, M. (2009). Odor identification deficit as a predictor of five-year global cognitive change: Interactive effects with age and ApoE-?4. Behavior Genetics, 39, 496-503.

Rönnlund, M., & Nilsson, L-G. (2009). Flynn effects on sub-factors of episodic and semantic memory: Parallel gains over time and the same set of determining factors. Neuropsychologia, 11, 2174-2188.

Bergdahl, M., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2008). Difference I apolipoprotein E type 4 allele (APOE-?4) among dentate and edentulous subjects. Gerodontology, 25(3), 179-186

de Frias, C.M., Bunce, D., Wahlin, Å., Adolfsson, R., Sleegers, K., Cruts, M., Van Broeckhoven, C., & Nilsson, L.-G. (2008). Cholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults. Journal of Gerontology: Psychological Sciences, 62, P112-P118.

Hansson, P., Rönnlund, M., Juslin, P., & Nilsson, L.-G. (2008). Adult age diffeerences in the realism of confidence judgments: Overconfidence, formal dependence, and cognitive predictors. Psychology and Aging, 23(3), 531-544.

Hedner, M., Nilsson, L.-G., Olofsson, J. et al. (2008). The BDNF Val66Met polymorphism influences olfactory processing. International Journal of Psychology, 43, 275-276.

Holmgren, S., Molander, B., & Nilsson, L.-G. (2008). Episodic memory in adult age and effects of sibship size and birth order: Longitudinal data. Journal of Adult Development, 14, 37-46.

Kask, K., Bäckström, T., Nilsson, L.-G., & Sundström-Poromaa, I. (2008). Allopregnanolone impairs episodic memory in healthy women. Psychpharmacology, 199(2), 161-168.

Kormi-Nouri, R., Shojaei, R.-S., Moniri, S., Gholami, A.-R., Moradi, A.-R., Akbari-Zardkhaneh, S., & Nilsson, L.-G. (2008). The effect of childhood bilingualism on episodic and semantic memory tasks. Scandinavian Journal of Psychology, 49(2), 93-109.

Olofsson, J., Rönnlund, M., Nordin, S., et al. (2008). Odor identification impairment predicts cognitive decline and Alzheimer's disease. International Journal of Psychology, 43, 469-469.

Persson, J., Lind, J., Larsson, A., Ingvar, M., Sleegers, K., Van Broeckhoven, C., Adolfsson, R., Nilsson, L.-G., & Nyberg, L. (2008). Altered deactivation in individuals with genetic risk for Alzheimer's disease. Neuropsychologia, 46, 1679-1687.

Rolandsson, O., Backeström, A., Eriksson, S., Hallmans, G., & Nilsson, L.-G. (2008). Increased glucose levels are associated with episodic memory in nondiabetic women. Diabetes, 57, 440-443.

Rönnlund, M., Lövdén, M., & Nilsson, L.-G. (2008). Cross-Sectional versus Longitudinal Age Gradients of Tower of Hanoi Performance: The Role of Practice Effects and Cohort Differences in Education. Aging, Neuropsychology and Cognition, 15, 40-67

Rönnlund, M., Mäntylä, T., & Nilsson, L.-G. (2008). The prospective and retrospective memory questionnaire (PRMQ): Factorial structure, relations to global subjective memory ratings, and Swedish norms. Scandinavian Journal of Psychology, 49, 11-18.

Rönnlund, M., & Nilsson, L.-G. (2008). The magnitude, generality, and determinants of Flynn effects on forms of declarative memory and visuospatial ability: Time-sequential analyses of data from a Swedish cohort study. Intelligence, 36, 192-209.

Sternäng, O., Wahlin, Å., & Nilsson, L.- G. (2008). Examination of the processing speed account in a population-based longitudinal study with narrow age cohort design. Scandinavian Journal of Psychology, 49(5), 419-428

Sundström, A., Nilsson, L.-G., Cruts, M., Adolfsson, R., Van Broeckhoven, C., & Nyberg, L. (2008). Fatigue before and after mild traumatic brain injury: Pre-post-injury comparisons in relation to ApolipoproteinE. Brain Injury, 1-6.

Wahlin, Å., Anstey, K., McDonald, S.W.S., Ahmed, S.M., Kivipelto, M., Kunnukattil, K.S.S., Mai, T.T., Nilsson, L.-G., Streatfield, P.K., van Boxtel, M.P., & Kabir, Z.N. (2008). The international network on public health and aging (INOPA): Introducing a life course perspective to the public health agenda. Journal of Cross-Cultural Gerontology, 23(1), 97-105.

Zhang, Y.M., Han, B., & Nilsson, L.-G. (2008). Executive functioning in older adults with mild cognitive impairment: MCI has effects on planning, but not on inhibition: Erratum. Aging, Neuropsychology and Cognition, 15(2), 256-256.

Bergdahl, M., Habib, R., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2007). Natural teeth and cognitive function in humans. Scandinavian Journal of Psychology, 48, 557-568.

de Frias, C. M., Lövdén, M., Lindenberger, U., & Nilsson, L.-G. (2007). Revisiting the dedifferention hypothesis with longitudinal multi-cohort data. Intelligence, 35, 381-392.

Habib, R., Nyberg, L., & Nilsson, L.-G. (2007). Cognitive and non-cognitive factors contributing to the longitudinal identification of successful older adults in the Betula study. Aging, Neuropsychology and Cognition, 14, 257-273.

Meyer, T. D., Hammelstein, P., Nilsson, L.-G., Skeppar, P., Adolfsson, R., & Angst, J. (2007). The Hypomania Checklist (HCL-32): Its factorial structure and association to indices of impairment in German and Swedish nonclinical samples. Comprehensive Psychiatry, 48, 79-87.

Nilsson, L.-G., & Larsson, M. (2007). Objective and subjective memory function for men and women in adulthood and old age. In S. Magnussen & T. Helstrup (Eds.), Everyday memory, pp. 275-290. London: Psychology Press

Sundström, A., Nilsson, L.-G., Cruts, M., Adolfsson, R., Van Broeckhoven, C., & Nyberg, L. (2007). Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE-?4 allele. International Psychgeriatrics, 19, 159-165.

Van Den Eede, F., Venken, T., Del-Favero, J., Norrback, K.-F., Souery, D., Nilsson, L.-G., Van den Bossche, B., Houlstijn, W., Sabbe, B. G. C., Cosyns, P., Mendlewicz, J., Adolfsson, R., Van Broeckhoven, C., & Claes, S. J. (2007). Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in recurrent major depressive disorder. Psychiatry Research, 153, 17-25.

Van Den Eede, F., Venken, T., Van Den Bogaert, A., Del-Favero, J., Norrback, K.-F., Nilsson, L.-G., Adolfsson, R., Van Broeckhoven, C., & Claes, S. J. (2007). Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in bipolar disorder. Psychiatry Genetics, 17, 304-307.

Öhman, L., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2007). Longitudinal analysis of the relation between moderate long-term stress and health. Stress and Health, 23, 131-138.

de Frias, C.M., Nilsson, L.-G., & Herlitz, A. (2006). Sex differences in cognition are stable over a 10-year period in adulthood and old age. Aging, Neuropsychology and Cognition, 13, 574-587.

Holmgren, S., Molander, B., & Nilsson, L.-G. (2006). Intelligence in adult age: Effects of sibship size and birth order. European Journal of Cognitive Psychology, 18, 138-158.

Launer, L.J., Berger, K., Breteler, M.M.B., Dufoil, C., Fuhrer, R., Giampoli, S., Nilsson, L.-G., Pajak, A., de Ridder, M., van Dijk, E.J., Sans, S., Schmidt, R., & Hofman, A. (2006). Regional variability in the prevalence of cerebral white matter lesions: An MRI study in 9 European countries (CASCADE). Neuroepidemiology. 26, 23-29.

Lind, J., Ingvar, M., Persson, J., Cruts, M., Van Broeckhoven, C., Adolfsson, R., & Nilsson, L.-G. (2006). Parietal cortex activation predicts longitudinal memory decline in APOE-?4 carriers. NeuroReport, 17, 1683-1686.

Lind, J., Persson, J., Ingvar, M., Larsson, A., Cruts, M., Van Broeckhoven, C., Adolfsson, R., Bäckman, L., Nilsson, L.-G., Petersson, K.M., & Nyberg, L. (2006). Reduced functional brain activity response in cognitively intact Apolipoprotein e4 carriers. Brain, 129, 1240-1248.

Magnussen, S., Andersson, J., Cornoldi, C., De Bini, R., Endestad, T., Goodman, G.S., Helstrup, T., Koriat, A., Larsson, M., Melinder, A., Nilsson, L.-G., Rönnberg, J., & Zimmer, H. (2006). What people believe about memory. Memory, 14, 595-613.

Nilsson, L.-G. (2006). Memory, aging, and dementia: The Betula Study. In S. Ballesteros (Ed.), Aging, cognition and neuroscience, pp. 51-52. Madrid: UNED Ediciones.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Nyberg, L., Small, B.J., & Van Broeckhoven, C. (2006). The influence of APOE status on episodic and semantic memory: Data from a population-based study. Neuropsychology, 20, 645-657.

Nilsson, L.-G., & de Frias, C.M. (2006). The effect of genetics and vascular health on memory functioning: The Betula Study. In Q. Jing, H.-C. Chen, G. d'Ydewalle, M.R. Rosenzweig, H. Zhang, & K. Zhang (Eds.), Proceedings of the 28th International Congress of Psychology, pp. 113-128. London: Psychology Press.

Nilsson, L.-G., & Rönnberg, J. (2006). Learning and memory. In K. Pawlik & G. d'Ydewalle (Eds.), Psychological concepts: An international historical perspective, pp. 223-236. Hove, UK: Psychology Press.

Persson, J., Lind, J., Larsson, A., Crutz, M., Van Broeckhoven, C., Adolfsson, R., Nilsson, L.-G., & Nyberg, L. (2006). Altered brain white-matter integrity in non-demented carriers of the APOE-?4 allele: A risk for Alzheimer's disease. Neurology, 66, 1029-1033.

Persson, J., Nyberg, L., Lind, J., Larssson A., Nilsson, L.-G., Ingvar, M., & Buckner, R.L. (2006). Structure -Function correlates of cognitive decline in aging. Cerebral Cortex, 16, 907-915.

Rönnlund, M., & Nilsson, L.-G. (2006). Adult life-span patterns in WAIS block design performance: Cross-sectional versus longitudinal age gradients and relations to demographic predictors. Intelligence, 34, 63-78.

Rönnlund, M., & Nilsson, L.-G. (2006). The Betula Study: Reliabilities and long-term stabilities of memory test performances over the adult lifespan. Baltic Journal of Psychology, 7, 6-14.

Söderfjell, S., Molander, B., Johansson, H., Barnekow-Bergkvist, M., & Nilsson, L.-G. (2006). Muscoskeletal pain and performance on cognitive tasks over the adult life span. Scandinavian Journal of Psychology, 47, 349-359.

Söderlund, H., Nilsson, L.-G., Berger, K., Breteler, M.M., de Ridder, M., Dufouil, C., Fuhrer, R., Giampaoli, S., Hofman, A., Pajak, A., Sans, S., Schmidt, R., & Launer, L. (2006). Cerebral changes on MRI and cognitive function: The CASCADE Study. Neurobiology of Aging, 27, 16-23.

Wahlin, Å., MacDonald, S.W.S., de Frias, C.M., Nilsson, L.-G., & Dixon, R.A. (2006). How health an biological age influences chronological age and sex differences in cognitive aging: Moderating, mediating, or both? Psychology and Aging, 21, 318-332.

Yonker, J.E., Adolfsson, R., Eriksson, E., Hellstrand, M., Nilsson, L.-G., & Herlitz, A. (2006). Hormone replacement therapy improves episodic memory performance in healthy postmenopausal women. Aging, Neuropsychology, and Cognition, 13, 291-307.

Yonker, J.E., Eriksson, E., Nilsson, L.-G., & Herlitz, A. (2006). Negative effects of testosterone on visuospatial ability in 35 to 80 year old men. Cortex, 42 376-386.

Annerbrink, K., de Frias, C.M., Westberg, L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2005). Catechol O-metyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adults. Nordic Journal of Psychiatry, 59, 405-405.

Bergdahl, J., Larsson, A., Nilsson, L.-G., Riklund Åhlström, K., & Nyberg, L. (2005). Treatment of chronic stress in employees: Subjective, cognitive, and neural correlates. Scandinavian Journal of Psychology, 46, 395-402.

de Frias, C.M., Annerbrink, K., Westberg, L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2005). Catechol O-Methyltransferase Val155Met polymorphism is associated with Cognitive performance in nondemented adults. Journal of Cognitive Neuroscience, 17, 1018-1025.

Lövdén, M., Bergman, L., Adolfsson, R., Lindenberger, U., & Nilsson, L.-G. (2005). Studying individual aging in an interindividual context: Typical paths of age-related, dementia-related, and mortality-related cognitive development in old age. Psychology and Aging, 20, 303-316.

Nilsson, L.-G. (2005). Nilsson, L.-G. (2005). Aging and brain degeneration. European Neuropsycho-pharmacology, 15, S101-S101., 15, S101-S101.

Nilsson, L.-G., Söderlund, H., Berger, K., Breteler, M., de Ridder, M., Dufoil, C., Fuhrer, R., Giampoli, S., Hofman, A., Pajak, A., Sans, S., Schmidt, R., & Launer, L. J. (2005). Cognitive test battery of CASCADE: Tasks and data. Aging, Neuropsychology and Cognition, 12, 32-56.

Persson, J., Bringlöv, E., Nilsson L.-G., & Nyberg, L. (2005). Herbal extracts and memory enhancement: Response to Scholey et al. Psychopharmacology, 179, 708-709.

Rademakers, R., Sleegers, K., Theuns, J., Van der Broeck, M., Kacem, S.B., Nilsson, L.-G., Adolfsson, R., van Duin, C.M., Van Broeckhoven, C., & Cruts, M. (2005). Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease. Nerobiology of Aging, 26, 1145-1151.

Rönnlund, M., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2005). Stability, growth, and decline in adult life-span development of declarative memory: Cross-sectional and longitudinal data from a population-based sample. Psychology and Aging, 20, 3-18.

Yonker, J.E., Nilsson, L.-G., Herlitz, A., & Anthenelli, R. (2005). Sex differences in episodic memory as a function of alcohol consumption. Alcohol and Alcoholism, 40, 201-207.

Chotai, J., Smedh, K., Johansson, C., Nilsson, L.-G., & Adolfsson, R. (2004). An epidemiological study on gender differences in self-reported seasonal changes in mood and behaviour in a general population of northern Sweden. Nordic Journal of Psychiatry, 58, 429-437.

Chotai, J., Smedh, K., Nilsson, L.-G., & Adolfsson, R. (2004). A dual vulnerability hypothesis for seasonal depression is supported by the seasonal pattern assessment questionnaire in relation to the temperament and character inventory of personality in a general population. Journal of Affective Disorders, 82, 61-70.

de Frias, C. M., Annerbrink, K., Westberg. L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2004). COMT gene polymorphism is associated with declarative memory in adulthood and old age. Behavior Genetics, 34, 533-539.

Dixon, R.A., Bäckman., L., & Nilsson, L.-G. (2004). New frontiers in cognitive aging. New York: Oxford University Press

Dixon, R.A., & Nilsson, L.-G. (2004). Don't fence us in: Probing the frontiers of cognitive aging. In R. A. Dixon, L. Bäckman, & L.-G. Nilsson (Eds.), New frontiers in cognitive aging, pp. 3-14. New York: Oxford University Press.

Larsson, M., Nilsson, L.-G., Olofsson, J., & Nordin, S. (2004). Demographic and cognitive predictors of cued odor identification - Evidence from a population-based study. Chemical Senses, 29, 547-554.

Lövdén, M., Rönnlund, M., Wahlin, Å., Bäckman, L., Nyberg, L., & Nilsson, L.-G. (2004). The Extent of Stability and Change in Episodic and Semantic Memory in Old Age: Demographic Predictor of level and Change. Journal of Gerontology: Psychological Sciences, 59, P130-P134.

Maitland, S. B., Herlitz, A., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2004). Selective sex differences in declarative memory. Memory and Cognition, 32, 1160-1169.

Nilsson, L.-G. (2004). The genetic contribution to individual differences in memory function. International Journal of Psychology, 39, 33-33.

Nilsson, L.-G. (2004). Memory and genes- is there an association? In W. Östreng (Ed.), Synergies. Oslo: Centre for Advanced Study.

Nilsson, L.-G. (2004). Våra långtidsminnen. [Our long-term memories]. Tvärsnitt, 3, 22-26.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Nyberg, L., Small, B.,J., & Van Broeckhoven, C. (2004). Impairment of episodic memory and word fluency in carriers of the APOE-?4 allele. Behavior Genetics, 34, 654-654.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., de Frias, C., Molander. B., & Nyberg, L. (2004). Betula: A prospective cohort study on memory, health and aging. Aging, Neuropsychology and Cognition, 11, 134-1

Persson, J., Bringlöv, E., Nilsson L.-G., & Nyberg, L. (2004). The memory enhancing effects of ginseng and gingko biloba in healthy volunteers. Psychopharmacology, 172, 430-434.

Schmidt, R., Launer, L. J., Nilsson, L.-G, Pajak, A., Sans, S., Berger, K., Breteler, M. M., de Ridder, M., Dufoil, C., Giampaoli, S., & Hofman, A. (2004). MRI of the brain in diabetes mellitus: the cardiovascular determinants of dementia (CASCADE) study. Diabetes, 53, 687-692.

Sundström, A, Marklund, P, Nilsson, L.-G., & Nyberg, L. (2004). ApoE influences on neuropsychological function after mild head injury: Within-person comparisons. Neurology, 62, 1963-1966.

Söderlund, H., Nyberg, L., Nilsson, L.-G., & Launer, L. J. (2004). Cerebral atrophy as predictor of cognitive performance in healthy Swedish adults from the Betula prospective cohort study of aging, memory and health. Acta Neurologica Scandinavica, 109, 398-406.

van Dijk, E.J., Breteler, M.M.B., Schmidt, R., Berger, K., Nilsson, L.-G., Ouderk, M., Pajak, A., Sans, S., de Ridder, M., Dufoil, C., Fuhrer, R., Giampaoli, S., Launer, L.J., & Hofman, A. (2004). The association between blood pressure, hypertension and cerebral white matter lesions: The CASCADE Study. Hypertension, 44, 625-630.

Yonker, J.E., Liu, W., Nilsson, L.-G., & Anthenelli, R.M. (2004). Influence of alcohol consumption on cognitive performance in age-and education-matched women. Alcoholism Clinical and Experimental Research, 28, 148A.

von Essen, J.D., & Nilsson, L.-G. (2003). Memory effects of motor activation in subject performed tasks and sign language. Psychological Bulletin & Review, 10, 445-449.

Hill, R. D., Nilsson, L.-G., Nyberg, L., & Bäckman, L. (2003). Cigarette smoking as a predictor of cognitive performance in healthy Swedish adults from the Betula prospective cohort study of aging, memory and health. Age and Aging, 32, 1-4.

Johansson, C., Willeit, M., Levitan, R., Partonen, T., Smedh, C., Praschak-Rieder, N., Neumeister, A., Masellis, M., Basile, V., Zill, P., Bondy, B., Paunio, T., Kasper, S., Van Broeckhoven, C., Nilsson, L.-G., Lam, R., Schalling, M., & Adolfsson, R. (2003). The serotonin transporter promoter repeat length polymorphism, seasonal affective disorder and seasonality. Psychological Medicine, 33, 785-792.

Karlsson, T., Johansson, I., Adolfsson, R., Nilsson, L.-G., & Dubuc, S. (2003). Recognition memory in Alzheimer's disease. A demonstration of a remarkable memory capacity in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 15, 6-9.

Larsson, M., Lövdén, M., & Nilsson L.-G. (2003). Sex differences in recollective experience for olfactory and verbal information. Acta Psychologica, 112, 89-103.

Larsson, M., Nyberg, L., Bäckman, L., Nilsson, L.-G. (2003). Effects on episodic memory of stimulus richness, intention to learn, and extra-study repetition: Similar profiles across the adult life span. Journal of Adult Development, 10, 67-73.

Melke, J., Westberg, L., Nilsson, S., Landén, M., Söderström, H., Baghaei, F., Rosmond, R., Holm, G., Björntorp, P., Nilsson, L.-G., Adolfsson, R., & Eriksson. E., (2003). A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women. Archives of General Psychiatry, 60, 1017-1023.

Nilsson, L.-G. (2003). Memory function in normal aging. Acta Neurologica Scandinavica, 107, 7-13.

Nyberg, L., Maitland, S.B., Rönnlund, M., Bäckman, L., Dixon, R., Wahlin, Å., & Nilsson, L.-G. (2003). Selective adult age differences in an age-invariant multi-factor model of declarative memory. Psychology & Aging, 18, 149-160.

Rönnlund, M., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2003). Recall of subject-performed tasks, verbal tasks, and cognitive activities across the adult life span: Parallel age-related deficits. Aging, Neuropsychology and Cognition, 10, 182-201.

Söderlund, H., Nyberg, L., Adolfsson, R., Nilsson, L.-G., & Launer, L. (2003). High prevalence of white-matter hyperintensities in normal aging: Relation to blood pressure and cognition. Cortex, 39, 1093-1105.

Yonker, J., Eriksson, E., Nilsson, L.-G. & Herlitz, A. (2003). Sex differences in episodic memory: Minimal influence of estradiol. Brain and Cognition, 52, 231-238.

Berger, K., Launer, L., Hofman, A., Breteler, M., Nilsson, L.-G., Söderlund, H., Schmidt, R., Giampoli, S., Sans, S., Fuhrer, R., Dufoil, C., & Pajak, A. (2002). The association between white matter lesions and cognitive function in a pooled analysis of European, population studies in the Cascade project. Neurobiology of Aging, 23, 443-443.

Van Gestel, S., Forsgren, T., Claes, S., Del-Avero, J., van Duijn, C. M., Sluijs, S., Nilsson, L.-G., Adolfsson, R., & Van Broeckhoven, C. (2002). Epistatic effect of genes from the dopamine and serotonine systems on the temperament traits of novelty seeking and harm avoidance. Molecular Psychiatry, 7, 448-450.

Karlsson, T., Börjesson, A., Adolfsson, R., & Nilsson, L.-G. (2002). Successive memory test performance and priming in Alzheimer's disease. Evidence from the word-fragment completion task. Cortex, 38, 341-355.

Lövdén, M., Rönnlund, M., & Nilsson, L.-G. (2002). Remembering and knowing in adulthood: Effects of enacted encoding and relations to processing speed. Aging, Neuropsychology and Cognition, 9, 184-200.

Nilsson, L.-G., Nyberg, L., & Bäckman, L. (2002). Genetic variation in memory functioning. Neuroscience and Biobehavioral Review, 26, 841-848.

Nilsson, L.-G., Bäckman, L., Cruts, M, Edvardsson, H., Nyberg, L., Van Broeckhoven, C., Adolfsson, R. (2002). Memory development in adulthood and old age: The Betula prospective cohort study. In P. Graf & N. Ohta (Eds.), Lifespan Development of Human Memory. Philadelphia: The MIT Press

Nilsson, L.-G. (2002). The role of genetics in understanding memory. In C. Von Euler & E. Hjelmquist (Eds.), Dyslexia and literacy: A tribute to Ingvar Lundberg, pp.192-205. London: Whurr Publishers.

Nyberg, L., Persson, J., & Nilsson, L.-G. (2002). Individual differences in memory enhancement by encoding enactment: Relationships to adult age and biological factors. Neuroscience and Biobehavioral Review, 26, 835-839.

Schalling, M., Johansson, C., Willeit, M., Smedh, C., Ekholm, J., Paunio, T., Lichterman, D., Praschak-Rieder, N., neumeister, A., Nilsson, L.-G., Kasper, S., Peltonen, L., Levitan, R., Del Favero, J., masellis, M., Basile, V., Zill, P., Bondy, B., Van Broeckhoven, C., Lam, R., Adolfsson, R., & Partonen, T. (2002). Circadian clock related polymorphisms and the serotonin transporter promoter in seasonal affective disorder and seasonality. American Journal of medical Genetics, 114, 727-728.

Sundström, A., Nilsson, L.-G., & Nyberg, L. (2002). Cognitive performance before and after mild head injury. Journal of cognitive neuroscience, B77 (suppl s), 60-60.

Wahlin, Å., Bäckman, L., Hultdin, J., Adolfsson, R., & Nilsson, L.-G. (2002). Reference values of serum levels of vitamin B12 and folic acid in a populationbased sample of adults between 35 and 80 years of age. Journal of Public Health and Nutrition, 5, 505-511.

Chotai, J., Forsgren, T., Nilsson, L.-G., & Adolfsson, R. (2001). Season of birth variation in the temperament and character inventory of personality in a general population. Neuropsychobiology, 44, 19-26.

Ericsson, K., Winblad, B., & Nilsson, L.-G. (2001). Human-figure-drawing and memory functioning across the adult life span. Archives of Gerontology and Geriatrics, 32, 151-166.

Maitland, S.B., Nyberg L., Herlitz A., Bäckman, L., & Nilsson L.-G. (2001). The structure of declarative memory: Sex differences and measurement equivalence in the Betula Study. The Gerontologist, 41, 223-224.

Nilsson, L.-G., & Söderlund, H. (2001). Aging, cognition, and health. In M. Naveh-Benjamin, M. Moscovitch, & H.L. Roediger, III (Eds.), Perspectives on human memory and cognitive aging: Essays in honor of Fergus Craik, pp. 253-264. London: Psychology Press.

Nilsson, L.-G., Van Broeckhoven. C., & Adolfsson, R. (2001). Genetic Contributions to Individual Differences in Memory Performance. European Psychologist, 6, 264-271.

Nyberg, L., Petersson, K.M., Nilsson, L.-G., Sandblom, J., Åberg, C., & Ingvar, M. (2001). Reactivation of Motor Brain Areas during Explicit Memory for Actions. NeuroImage, 14, 521-528.

Rönnlund, M., Lövdén, M., & Nilsson, L.-G. (2001). Adult Age Differences in Tower of Hanoi Performance: Influence from Demographic and Cognitive Variables. Aging, Neuropsychology, and Cognition, 8, 269-283.

Hultdin, J., Wahlin, Å., Bäckman, L., Edvardsson, H., Adolfsson, R., & Nilsson, L.-G. (2000). Vitamin B12, folate and homocysteine as markers of cognitive defects: The Betula project. International Journal of Psychology, 35, 366.

Launer, L., Oudkerk, M., Nilsson, L.-G., Alperovitch, A., Berger, K., Breteler, M.M.B., Fuhrer, R., Giampaoli, S., Nissinen, A., Pajak, A., Sans, S., Schmidt, R., & Hofman, A. (2000). CASCADE: A European collaborative study on vascular determinants of brain lesion: Study design and objectives. Neuroepidemiology, 19, 113-120.

Lövdén, M., Rönnlund, M., Söderlund, H., Persson, J., Hasnoot, A., & Nilsson, L.-G. (2000). Cross-sectional and longitudinal patterns in explicit and implicit memory: Evidence from the Betula Study. International Journal of Psychology, 35, 366.

Maitland, S., Bäckman, L., Dixon, R., Hultsch, D., Nilsson, L.-G., & Wahlin, Å. (2000). Health-gender relationships: Tests of equivalence across cultures. International Journal of Psychology, 35, 367.

Molander, B., Andersson, R., Forsgren, L., Hilmgren, S., Marklund, P., & Nilsson, L.-G. (2000). Subjective health as a function of age and time of measurement. International Journal of Psychology, 35, 367.

Nilsson, L.-G. (2000). Can genes teach us anything about memory? In E. Tulving (Ed.), Memory, consciousness, and the brain: The Tallinn conference, pp. 28-37. Philadelphia: Psychology Press.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Edvardsson, H., Nyberg, L., & Van Broeckhoven, C. (2000).The roles of apolipoproteinE and memory as predictors for dementia in a nondemented population: The Betula study. International Journal of Psychology, 35, 366.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Molander, B., Nyberg, L., Smedberg-Åman, G, Widing, M., Söderlund, A. -L., Säfström, B., & Norin, E. (2000). The Betula study: Objectives, Assessment, and Design. International Journal of Psychology, 35, 234.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Edvardsson, H, Nyberg, L., & Van Broeckhoven, C. (2000). Normal memory development and the role of apolipoproteinE: The Betula study. International Journal of Psychology, 35, 366.

Nilsson, L.-G., Nyberg, L., Klingberg, T., Åberg, C., Persson, J., & Roland, P. (2000). Activity in motor areas while remembering action events. NeuroReport, 11, 2199-2201.

Nyberg., L., Maitland, S., Rönnlund, M., Bäckman, L., Dixon, R., Wahlin, Å., & Nilsson, L.-G. (2000). The structure of declarative memory: Competing theoretical models and measurement equivalence. International Journal of Psychology, 35, 365.

Rönnlund, M., Bäckman, L., Nyberg, L., Lövdén, M., & Nilsson, L.-G. (2000). Five-year changes in recall across levels of support: Parallel age-related deficits. International Journal of Psychology, 35, 366.

Rönnlund, M., Lövdén, M., Ljungberg, J., Nordin, M., & Nilsson, L.-G. (2000). Adult age differences in Tower of Hanoi performance: Evidence from the Betula prospective cohort study. International Journal of Psychology, 35, 366.

Söderfjell, S., Molander, B., Barnekow-Bergkvist, M., Lyskov, E., Johansson, H., & Nilsson, L.-G. (2000). Aging, stress, and musculosceletal problems. International Journal of Psychology, 35, 367.

Söderlund, H., Nyberg, L., Smedberg-Åman, G., Sundbaum-Åström, M., Sundström, I. -M., Widing, M., & Nilsson, L.-G. (2000). Effects of white matter lesions on cognition: Swedish CASCADE data. International Journal of Psychology, 35, 367.

Yonker, J., Nilsson, L.-G., Staaf, E., & Herlitz, A. (2000). Estradiol does not contribute significantly to episodic memory differences in men and women. International Journal of Psychology, 35, 368.

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Bäckman, L., & Nilsson, L.-G. (1996). Semantic memory functioning across the adult life span. European Psychologist, 1, 27-33.

Erngrund, K., Mäntylä, T., & Rönnlund, M. (1996). Acting or listening: Adult age differences in source recall of enacted and nonenacted statements. Journal of Adult Development, 3, 217-232

Erngrund, K., Nilsson, L.-G., & Mäntyla, T. (1996). Adult age differences in source memory: A population based study. Journal of Gerontology: Psychological Scieneces, 51B, P335-P345.

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Nyberg, L., Bäckman, L., Erngrund, K., Olofsson, U., & Nilsson, L.-G. (1996). Age differences in episodic memory, semantic memory, and priming: Relationships to biological, demographic, and psychometric variables. Journal of Gerontology: Psychological Sciences, 51B, P234-240.

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Herlitz, A., Bäckman, L., & Nilsson, L.-G. (1997). Gender differences in episodic memory. Memory & Cognition, 25, 801-811.

Mäntylä, T., & Nilsson, L.-G. (1997). Remembering to remember in adulthood: A population-based study on aging and prospective memory, manuscript. Aging, Neuropsychology, & Cognition, 4, 81-92.

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If you have published anything based on this study, please send a notification with a reference to your publication(s) to snd@snd.gu.se.

Dataset EXT 0045-001

Betula - aging, memory and dementia: 1988-1990

Collection events:

1988 - 1990 (Self-administered questionnaire)

1988 - 1990 (Physical measurements and tests)

1988 - 1990 (Psychological measurements and tests)

Dataset EXT 0045-002

Betula - aging, memory and dementia: 1993-1995

Collection events:

1993 - 1995 (Self-administered questionnaire)

1993 - 1995 (Physical measurements and tests)

1993 - 1995 (Psychological measurements and tests)

Dataset EXT 0045-003

Betula - aging, memory and dementia: 1998-2000

Collection events:

1998 - 2000 (Self-administered questionnaire)

1998 - 2000 (Physical measurements and tests)

1998 - 2000 (Psychological measurements and tests)

Dataset EXT 0045-004

Betula - aging, memory and dementia: 2003-2005

Collection events:

2003 - 2005 (Self-administered questionnaire)

2003 - 2005 (Physical measurements and tests)

2003 - 2005 (Psychological measurements and tests)

Dataset EXT 0045-005

Betula - aging, memory and dementia: 2008-2010

Collection events:

2008 - 2010 (Self-administered questionnaire)

2008 - 2010 (Physical measurements and tests)

2008 - 2010 (Psychological measurements and tests)

Dataset EXT 0045-006

Betula - aging, memory and dementia: 2013-2014

Collection events:

2013 - 2014 (Self-administered questionnaire)

2013 - 2014 (Physical measurements and tests)

2013 - 2014 (Psychological measurements and tests)