H70

Principal investigator(s):

Ingmar Skoog - University of Gothenburg, Institute of Neuroscience and Physiology

Abstract:

H70 is one of the longitudinal population studies from Gothenburg where representative study samples of older people have been followed over a long period of time (metadata related to the H85, 95+ and Prospective Population Study of Women studies can be found under the Related studies tab). H70 is a population-based study of normative aging in 70 year old populations which focuses on both medical and cognitive measures. H70 started in 1971 with the recruitment of 973 70-year-olds born in 1901-02 and participants have been intermittently followed for up to 30 years. Additional birth cohorts of 70-year-olds as well as 75-year-olds have also been studied and all cohorts have been followed to some extent longitudinally. The H70 study is coordinated by several research groups, primarily Geriatrics, Primary Health Care, Psychiatry, and Epidemiology. The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, a close informant interview, blood samples with ext

... Show more..

Contact:

Ingmar Skoog

Principal organisation:

Available documentation:

Identifiers:

SND-ID:

Principal investigator(s):

Ingmar Skoog - University of Gothenburg, Institute of Neuroscience and Physiology

Principal organisation:

Purpose:

The original aim was: 1. To contribute to the knowledge of normal ageing processes and of normal conditions within the age group 2. To make a survey of the social and medical conditions of the population. 3. To obtain basic data for planning the care of the elderly and 4. To offer the subjects a thorough medical examination

Abstract:

H70 is one of the longitudinal population studies from Gothenburg where representative study samples of older people have been followed over a long period of time (metadata related to the H85, 95+ and Prospective Population Study of Women studies can be found under the Related studies tab). H70 is a population-based study of normative aging in 70 year old populations which focuses on both medical and cognitive measures. H70 started in 1971 with the recruitment of 973 70-year-olds born in 1901-02 and participants have been intermittently followed for up to 30 years. Additional birth cohorts of 70-year-olds as well as 75-year-olds have also been studied and all cohorts have been followed to some extent longitudinally. The H70 study is coordinated by several research groups, primarily Geriatrics, Primary Health Care, Psychiatry, and Epidemiology. The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, a close informant interview, blood samples with ext

... Show more..

Time period(s) investigated:

1971 — ongoing

Instrument:

Geographic location:

Geographic description:

Gothenburg

Lowest geographic unit:

Municipality

Unit of analysis:

Population:

The population originally consisted of a representative sample of 70-year-old men and women born in 1901/1902 and living in Gothenburg 1971/1972.

Time Method/Study design:

Sampling procedure:

Probability: Systematic random
The study participants were mainly drawn as a representative, systematic sample from the population register.

Publications

Sort by name | Sort by year

Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. Acta Med Scand. 1975 Nov;198(5):397-407.

Nilsson L, Persson G. H70 Hälsoundersökning av 70-åringar i Göteborg. Mentalt hälsotillstånd. Läkartidn 1980;77:3757-3759.

Persson G. Life event ratings in relation to sex and marital status in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:112-118.

Persson G. Personality dimensions in a 70-year-old urban population. Norms for the MNT scales and sex and age relations. Acta Psychiatr Scand 1980;62:476-485.

Persson G. Prevalence of mental disorders in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:119-139.

Persson G. Psychogenic needs in a 70-year-old population. Norms for the CMPS and sex and age relations. Acta Psychiatr Scand 1980;62:464-475.

Persson G. Relation between early parental death and life event ratings among 70-year-olds. A test of a sensitization theory. Acta Psychiatr Scand 1980;62:392-397.

Persson G. Sexuality in a 70-year-old urban population. J Psychosom Res 1980;24:335-342.

Berg S, Mellström D, Persson G, Svanborg A. Loneliness in the Swedish aged. J Gerontol 1981;36:342-349.

Persson G. Five-year mortality in a 70-year-old urban population in relation to psychiatric diagnosis, personality, sexuality and early parental death. Acta Psychiatr Scand 1981;64:244-253.

Nilsson L. Mental diseases in an urban population examined at the age of 70 and 5 years later. Nordisk Gerontologisk Tidskrift, Norsam-Nyt Suppl 1982;42-43.

Nilsson LV. Prevalence of mental disorders in a 70-year-old urban sample. A cohort comparison. J Clin Exp Gerontology 1983;5:101-120.

Persson G, Nilsson LV, Svanborg A. Personality and sexuality in relation to an index of gonadal steroid hormone balance in a 70-year-old population. J Psychosom Res 1983;27:469-477.

Nilsson LV, Persson G. Prevalence of mental disorders in an urban sample examined at 70, 75 and 79 years of age. Acta Psychiatr Scand 1984;69:519-527.

Nilsson LV. Incidence of severe dementia in an urban sample followed from 70 to 79 years of age. Acta Psychiatr Scand 1984;70:478-486.

Frändin K, Grimby G, Mellström D, Svanborg A. Walking habits and health-related factors in a 70-year-old population. Gerontology 1991; 37: 281-8.

Persson G, Svanborg A. Marital coital activity in men at the age of 75: relation to somatic, psychiatric, and social factors at the age of 70. A prospective study on a representative material. J Am Geriatr Soc 1992;40:439-444.

Sonn U, Frändin K, Grimby G. Instrumental activities of daily living related to impairments and functional limitations in 70-year-olds and changes between 70 and 76 years of age. Scand J Rehab Med 1995; 27: 119-28.

Palsson SP, Östling S, Skoog I. The incidence of first-onset depression in a population followed from the age of 70 to 85. Psychol Med 2001;31:1159-1168.

Ruitenberg A, Skoog I, Ott A, Aevarsson O, Witteman JC, Lernfelt B, van Harskamp F, Hofman A, Breteler MMB. Blood Pressure and Risk of Dementia: Results from the Rotterdam Study and the Gothenburg H-70 Study. Dement Geriatr Cogn Disord 2001;12:33-39.

Silveira E, Skoog I, Sundh V, Allebeck P, Steen B. Health and well-being among 70-year-old migrants living in Sweden – results from the H70 gerontological and geriatric population studies in Göteborg. Soc Psychiatry Psychiatr Epidemiol 2002;37:13-22.

Bergh I, Steen G, Waern M, Sjöström B, Odén A, Steen B. Pain and depressive symptoms in 70-year old men and women: A Swedish population study. Journal of pain and symptom management 2003;26:903-912.

Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr 2003;36:127-140.

Skoog I. Psychiatric epidemiology of old age: the H70 study - the NAPE Lecture 2003. Acta Psychiatr Scand. 2004;109:4-18.

Liebetrau M, Hamann GF, Skoog I. White matter lesions as a risk factor for stroke and dementia. Nervenarzt 2005;76:708-715.

Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc 2006;54:975-979.

Östling S, Pálsson S, Skoog I. The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry 2007;22:520-528.

Beckman N, Waern M, Gustafson D, Skoog I. Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: cross sectional survey of four populations, 1971-2001. Brit Med J 2008; 337:151–154.

Duberstein PR, Palsson SP, Waern M, Skoog I. Personality and risk for depression in a birth cohort of 70-year-olds followed for 15 years. Psychological Medicine 2008;38:663-671.

Karlsson B, Klenfeldt IF, Sigstrom R, Waern M, Ostling S, Gustafson D, Skoog I. Prevalence of social phobia in non-demented elderly from a swedish population study. Am J Geriatr Psychiatry 2009;17:127-135.

Sigström R, Skoog I, Sacuiu S, Karlsson B, Fredén Klenfeldt I, Waern M, Gustafson D, Östling S. The prevalence of psychotic symptoms and paranoid ideation in a non-demented population sample of 70- 82 year olds. Int J Ger Psychiatry 2009;24:1413-1419.

Sacuiu S, Gustafson D, Johansson B, Thorvaldsson V, Berg S, Sjögren M, Guo X, Östling S, Skoog I. The pattern of cognitive symptoms predicts time to dementia onset. Alz & Dem 2009;5:199-206.

Karlsson B, Sigström R, Waern M, Östling S, Gustafson D, Skoog I. The Prognosis and Incidence of Social Phobia in an Elderly Population. A 5-Year Follow-up. Acta Psych Scand 2010; 122:4-10.

Sacuiu S, Gustafson D, Sjögren M, Guo X, Östling S, Johansson B, Skoog I. Secular changes in cognitive predictors of dementia and mortality in 70-year-olds. Neurology 2010;75(9):779-85.

Olesen PJ, Gustafson DR, Simoni M, Pantoni L, Ostling S, Guo X, Skoog I. Temporal Lobe Atrophy and White Matter Lesions are Related to Major Depression over 5 years in the Elderly. Neuropsychopharmacology 2010;35(13):2638-45.

Sigström R, Ostling S, Karlsson B, Waern M, Gustafson D, Skoog I. A population-based study on phobic fears and DSM-IV specific phobia in 70-year olds. J Anxiety Disord. 2011;25(1):148-53. .

Hörder H, Skoog I, Frändin K. Health-related quality of life in relation to walking habits and fitness: a population-based study of 75-year-olds. Qual Life Res. 2013 Aug;22(6):1213-23. doi: 10.1007/s11136-012-0267-7. Epub 2012 Sep 22.

Kern S, Skoog I, Ostling S, Kern J, Börjesson-Hanson A. Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk? A 5-year follow-up of a non-demented population-based cohort of Swedish elderly women. BMJ Open. 2012 Oct 3;2(5). doi:pii: e001288. 10.1136/bmjopen-2012-001288. Print 2012. PubMed PMID: 23035037; PubMed Central PMCID: PMC3488756.

Fredén Klenfeldt I, Karlsson B, Sigström R, Waern M, Östling S, Marlow T, Gustafson D, Skoog I. Prevalence of Obsessive-compulsive Disorder in Relation to Depression and Cognition in an Elderly Population. Am J Geriatr Psychiatry. 2014 Mar;22(3):301-8. doi: 10.1016/j.jagp.2012.09.004. Epub 2013 Mar 13.

Lak V, Guo X, Skoog I. Secular trends in lung function and its relation to survival in Swedish 75-year olds 1976-2006. Age Ageing. 2012 Nov;41(6):735-40.

Mosallanezhad Z, Hörder H, Salavati M, Nilsson-Wikmar L, Frändin K. Physical activity and physical functioning in Swedish and Iranian 75-year-olds – a comparison. Arch Gerontol Geriatr 2012; 55(2): 422-30.

Nilsson J, Östling S, Waern M, Karlsson B, Sigström R, Guo X, Skoog I. The 1-Month Prevalence of Generalized Anxiety Disorder According to DSM-IV, DSM-V, and ICD-10 Among Nondemented 75-Year-Olds in Gothenburg, Sweden. Am J Geriatr Psychiatry. 2012 Nov;20(11):963-72. doi: 10.1097/JGP.0b013e318252e749.

Thorvaldsson V, Skoog I, Hofer SM, Börjesson-Hanson A, Ostling S, Sacuiu S, Johansson B. Nonlinear blood pressure effects on cognition in old age: separating between-person and within-person associations. Psychol Aging. 2012 Jun;27(2):375-83. Epub 2011 Oct 10.

Billstedt E, Waern M, Duberstein P, Marlow T, Hellström T, Östling S, Skoog I. Secular changes in personalty: study of 75-year-olds examined in 1976-1977 and 2005-2006. In J Geriatr Psychiatry 2013;28(3):298-304.

Sjöberg L, Östling S, Waern M, Falk H, Skoog I. Secular changes in the relation between depression and social factors. A study of two birth cohorts of Swedish septuagenarians followed for 5 years. J Affect Disord. 2013 Sep 5;150(2):245-52. doi: 10.1016/j.jad.2013.04.002. Epub 2013 Apr 30.

Waern M, Marlow T, Östling S, Morin J, Skoog I. Secular changes in at-risk drinking in Sweden: Birth cohort comparisons in 75-year-old men and women 1976-2006. Age Ageing. 2014 Mar;43(2):228-34. doi: 10.1093/ageing/aft136. Epub 2013 Sep 25.

Wiberg P, Waern M, Billstedt E, Östling S, Skoog I. Secular trends in the prevalence of dementia and depression in Swedish septugenarians 1976- 2006. Psychol Med. 2013 Dec;43(12):2627-34. doi: 10.1017/S0033291713000299. Epub 2013 Mar 12.

Zhi X, Joas E, Waern M, Östling S, Börjesson-Hanson A, Skoog I. Prevalence of cardiovascular disorders and risk factors in two 75-year-olds birth cohorts examined in 1976-77 and 2005-06. Aging Clin Exp Res. 2013 Aug;25(4):377-83. doi: 10.1007/s40520-013-0058-1. Epub 2013 Jun 4.

Landahl S, Lindblad B, Roupe S, Steen B, Svanborg A. Digitalis therapy in a 70-year-old population. Acta Med Scand. 1977;202(6):437-43.

Steen B, Isaksson B, Svanborg A. Intake of energy and nutrients and meal habits in 70-year-old males and females in Gothenburg, Sweden. A population study. Acta Med Scand Suppl. 1977;611:39-86.

Steen B, Bruce A, Isaksson B, Lewin T, Svanborg A. Body composition in 70-year-old males and females in Gothenburg, Sweden. A population study. Acta Med Scand Suppl. 1977;611:87-112.

Landahl S, Jagenburg R, Svanborg A. Blood components in a 70-year-old population. Clin Chim Acta. 1981 May;112(3):301-14.

Mellström D, Rundgren A, Jagenburg R, Steen B, Svanborg A. Tobacco smoking, ageing and health among the elderly: a longitudinal population study of 70-year-old men and an age cohort comparison. Age Ageing. 1982 Feb;11(1):45-58.

Nilsson-Ehle H, Jagenburg R, Landahl S, Svanborg A, Westin J. Haematological abnormalities and reference intervals in the elderly. A cross-sectional comparative study of three urban Swedish population samples aged 70, 75 and 81 years. Acta Med Scand. 1988;224(6):595-604.

Nilsson-Ehle H, Jagenburg R, Landahl S, Svanborg A, Westin J. Decline of blood haemoglobin in the aged: a longitudinal study of an urban Swedish population from age 70 to 81. Br J Haematol. 1989 Mar;71(3):437-42.

Nilsson-Ehle H, Jagenburg R, Landahl S, Svanborg A. Blood haemoglobin declines in the elderly: implications for reference intervals from age 70 to 88. Eur J Haematol. 2000 Nov;65(5):297-305.

Nilsson L, Skoog I. H-70 - de äldres hälsa. Fler resultat från projektet: Psykiska störningar. Läkartidningen 1989;86:2773-2774.

If you have published anything based on this study, please send a notification with a reference to your publication(s) to snd@snd.gu.se.

Dataset EXT 0203-001

H70, cohort 1: 70-year-olds born in 1901-02

Description:

The baseline health examination survey in 1971/72 involved 973 individuals (449 men and 524 women), which represented a response rate of 84% in total. Participants were followed up at age 75, 79, 81, 82, 83, 85, 88, 90, 92, 95, 97, 99, 100 and 101 years of age. The study surveys have been conducted in 1971-72, 1976-77, 1980, 1982-83, 1984-85, 1986-87, 1989-90, 1991, 1993, 1996, 1998, 2000, 2001 and 2002. In connection with other studies the study samples have occasionally been expanded with new entrants who have not previously participated in the survey.

Collection methodology:

A representative, systematic sample of 70-year-olds was drawn from the population register. Those born between July 1, 1901 and June 30, 1902 on dates ending with 2, 5 or 8, were selected and invited to a health examination. Participants were given numbers from 1 to 5 in order to facilitate subsampling. Participants were first contacted by letter in which they were offered a health check. The first part of the data collection was through home visits by a nurse who conducted an interview with the participant and performed a basic examination. At the home visit a date for further examination, including physiological testing, biological sampling, and additional interviews at the hospital were agreed on. In addition, data from official records were collected.

Time period(s) investigated:

1971 — 2002

Dataset EXT 0203-002

H70, cohort 2: 70-year-olds born in 1906/07

Description:

At the 1976-77 baseline health examination 1036 individuals participated (474 men and 562 women), which represents a response rate of 81% in total. Participants were followed up at 75, 79, and 95 years of age. The study surveys have been conducted in 1976, 1981, 1985 and 2001.

Collection methodology:

In 1976-1977 a representative, systematic sample of 70-year-olds was drawn from the population register by selecting those born between July 1, 1906 and June 30, 1907 on dates ending with 2, 5 or 8. Participants were first sent a letter in which they were invited to a medical examination. Data collection was performed in a similar manner to that described for the first cohort.

Time period(s) investigated:

1976 — 2001

Dataset EXT 0203-003

H70, cohort 3: 70-year-olds born in 1911/12

Description:

At the 1981-82 baseline health examination 619 individuals participated (302 men and 317 women), which represents a response rate of 77% in total. Participants were followed up at the 72 and 76 years of age. The study surveys have been conducted in 1981, 1983 and in 1987.

Collection methodology:

In 1981-82 70-year-olds born in 1911/1912 were sampled. This cohort included participants from the intervention study of elderly people in Gothenburg (IVEG). Data collection was performed in a similar manner to that described for the first cohort.

Time period(s) investigated:

1981 — 1987

Dataset EXT 0203-004

H70, cohort 4: 75-year-olds born in 1915/16

Description:

In 1990 a cohort of 75-year-olds born in 1915 were included in the H70 study. These individuals were also part of the Nordic study NORA, which is a side-examination of H70. At baseline 323 individuals participated (143 men and 180 women), which represents a response rate of 72% in total. Participants were followed up at age 80. The study surveys have been conducted in 1990 and 1995.

Collection methodology:

A random sample of 75-year-olds in Gothenburg was made in 1990. This included a cohort that was part of the H70 study as well as in the Nordic study NORA. Data collection was performed in a similar manner to that described for the first cohort.

Time period(s) investigated:

1990 — 1995

Dataset EXT 0203-005

H70, cohort 5: 70-year-olds born in1922

Description:

In 1992 another cohort aged 70 was included in H70. At the 1992-93 baseline examination 500 individuals participated (201 men and 299 women), representing a response rate of 66% in total. Participants were followed up at age 78, 83, and 87. The study surveys have been conducted in 1992, 2000, 2005 and 2009.

Collection methodology:

Similar to earlier H70 examinations a representative and systematic sample of 70-year-olds was taken from the population register. A subgroup of the women in the cohort were selected based on previous inclusion in the Prospective Population Study of Women in Gothenburg (PPSW). These women were selected from the population register in 1968 and have been followed up regularly ever since.

Time period(s) investigated:

1992 — ongoing

Dataset EXT 0203-006

H70, kohort 6: 70-year-olds born in 1930

Description:

At the 2000-01 baseline examination 574 individuals participated (243 men and 331 women), which represents a response rate of 65% in total. Study participants were followed up at age 75 and 79. Surveys have been conducted in 2000, 2005 and 2009.

Collection methodology:

In 2000/2001 all 70-year-olds born in 1930 on dates 3, 6, 12, 18, 21, 24, 30 and living in Gothenburg, (September 1, 2000) were invited to a health examination. A subset of women was enrolled based on previous participation in the Prospective Population Study of Women in Gothenburg (PPSW). These women were selected from the population register in 1968 and have since been followed up regularly.

Time period(s) investigated:

2000 — ongoing

Dataset EXT 0203-007