Malmö Preventive Project

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Jonas Manjer - Lund University, Faculty of Medicine

Olle Melander - Lund University, Faculty of Medicine

Peter M Nilsson - Lund University, Faculty of Medicine

Description

The MPP was started in the early 70's as a screening survey in the middle-aged population of Malmö, the third largest city of Sweden. Subjects born in Malmö and residents of the city were invited for a clinical examination, questionnaire and blood sampling. In all 22,444 men and 10,902 women participated during the period 1974-1992. During a later follow-up, the MPP-Re-examination (MPP-RES) in all 17,284 of the original screenes attended in 2002-2006.

Purpose:

1. To screen for cardiovascular risk-factors and alcohol abuse in the local population, and to offer intervention to subjects at risk;








2. To use DNA (at MPP-RES) for analyses of genetic risks of type-2 diabetes and cardiovascular disease, as well as some cancers.

Subject area

Responsible department/unit

Lund University, Faculty of Medicine

Creator/Principal investigator(s)

Jonas Manjer - Lund University, Faculty of Medicine

Olle Melander - Lund University, Faculty of Medicine

Peter M Nilsson - Lund University, Faculty of Medicine

Identifiers

SND-ID: EXT 0013

Description

The MPP was started in the early 70's as a screening survey in the middle-aged population of Malmö, the third largest city of Sweden. Subjects born in Malmö and residents of the city were invited for a clinical examination, questionnaire and blood sampling. In all 22,444 men and 10,902 women participated during the period 1974-1992. During a later follow-up, the MPP-Re-examination (MPP-RES) in all 17,284 of the original screenes attended in 2002-2006.

Purpose:

1. To screen for cardiovascular risk-factors and alcohol abuse in the local population, and to offer intervention to subjects at risk;








2. To use DNA (at MPP-RES) for analyses of genetic risks of type-2 diabetes and cardiovascular disease, as well as some cancers.

Time period(s) investigated

1974 — 2006

Geographic spread

Geographic location: Sweden

Geographic description: Municipality of Malmö

Unit of analysis

Population

Individuals at age 35-70 y at first screening living in Malmö

Sampling procedure

Total universe/Complete enumeration

Subject area

Contact for questions about the data

Olle Melander

Is part of collection at SND

Scania Metadatabase for Epidemiology (SME)

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Publications

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Nilsson PM, Nilsson JA, Berglund G. Population-attributable risk of coronary heart disease risk factors during long-term follow-up: the Malmö Preventive Project. J Intern Med 2006;260:134-41.

Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, Berglund G, Altshuler D, Nilsson P, Groop L. Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 2008;359:2220-32.

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Dataset 1

Malmö Preventive Project

Creator/Principal investigator(s)

Jonas Manjer - Lund University, Faculty of Medicine

Olle Melander - Lund University, Faculty of Medicine

Peter M Nilsson - Lund University, Faculty of Medicine

Data format / data structure

Numeric

Data collection

Mode of collection: Self-administered questionnaire: paper

Time period(s) for data collection: 1974 — 1991

Source of the data: Population group

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 1974 — 1991

Source of the data: Population group

Number of individuals/objects

33346

Response rate/participation rate

70%

Dataset 2

Malmö Preventive Project

Creator/Principal investigator(s)

Jonas Manjer - Lund University, Faculty of Medicine

Olle Melander - Lund University, Faculty of Medicine

Peter M Nilsson - Lund University, Faculty of Medicine

Data format / data structure

Numeric

Data collection

Time period(s) for data collection: 2002 — 2006

Source of the data: Population group

Mode of collection: Self-administered questionnaire: paper

Time period(s) for data collection: 2002 — 2006

Source of the data: Population group

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2002 — 2006

Source of the data: Population group

Number of individuals/objects

17284

Response rate/participation rate

67 %

Published: 2011-01-01
Last updated: 2017-03-29