PcBaSe Sweden

Creator/Principal investigator(s):

Pär Stattin - Umeå University, Department of Surgical and Perioperative Sciences orcid

Hans Garmo - Uppsala Academic Hospital, Regional Oncologic Center

Jan Adolfsson - Karolinska Institute, Department of Clinical Science, Intervention and Technology

Anna Bill-Axelsson - Uppsala University, Department of Surgical Sciences

Olof Akre - Karolinska Institute, Department of Medicine, Solna

Mats Lambe - Karolinska Institutet, Department of Medical Epidemiology and Biostatistics

Description:

PcBaSe Sweden is a data base for clinical epidemiological prostate cancer research based on linkages between the National Prostate Cancer Register (NPCR) of Sweden, a nationwide population-based quality database and other nationwide registries. In the period 1996-2009, 110 000 cases have been registered in NPCR with detailed data on tumour characteristics and primary treatment available. In addition, there are five controls per case.

By use of the individually unique person identity number, the NPCR has been linked to the Swedish National Cancer Register, the Cause of Death Register, the Prescribed Drug Register, the National Patient Register, and the Acute Myocardial Infarction Register, the Register of the Total Population, the Longitudinal Integration database for health insurance and labour market studies (LISA), the Multi-Generation Register and several other population-based registers.

Creator/Principal investigator(s):

Pär Stattin - Umeå University, Department of Surgical and Perioperative Sciences orcid

Hans Garmo - Uppsala Academic Hospital, Regional Oncologic Center

Jan Adolfsson - Karolinska Institute, Department of Clinical Science, Intervention and Technology

Anna Bill-Axelsson - Uppsala University, Department of Surgical Sciences

Olof Akre - Karolinska Institute, Department of Medicine, Solna

Mats Lambe - Karolinska Institutet, Department of Medical Epidemiology and Biostatistics

Identifiers:

SND-ID: EXT 0014

Purpose:

To provide a platform for prostate cancer research. The data base allows for population-based observational studies with case-control, cohort, or longitudinal case only design that can be used for studies of pertinent issues of clinical importance.

Description:

PcBaSe Sweden is a data base for clinical epidemiological prostate cancer research based on linkages between the National Prostate Cancer Register (NPCR) of Sweden, a nationwide population-based quality database and other nationwide registries. In the period 1996-2009, 110 000 cases have been registered in NPCR with detailed data on tumour characteristics and primary treatment available. In addition, there are five controls per case.

By use of the individually unique person identity number, the NPCR has been linked to the Swedish National Cancer Register, the Cause of Death Register, the Prescribed Drug Register, the National Patient Register, and the Acute Myocardial Infarction Register, the Register of the Total Population, the Longitudinal Integration database for health insurance and labour market studies (LISA), the Multi-Generation Register and several other population-based registers.

Geographic spread:

Geographic location: Sweden

Geographic description: Sweden

Lowest geographic unit:

Country

Unit of analysis:

Population:

Swedish men

Contact person for questions about the data:

Pär Stattin

Publications

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Hagel E, Garmo H, Bill-Axelson A, Bratt O, Johansson JE, Adolfsson J, Lambe M, Stattin P. PCBaSe Sweden: a register-based resource for prostate cancer research. Scand J Urol Nephrol. 2009;43(5):342-9.

Van Hemelrijck M, Adolfsson J, Garmo H, Bill-Axelson A, Bratt O, Ingelsson E, Lambe M, Stattin P, Holmberg L. Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden. Lancet Oncol. 2010 May;11(5):450-8.

Bill-Axelson A, Garmo H, Lambe M, Bratt O, Adolfsson J, Nyberg U, Steineck G, Stattin P. Suicide risk in men with prostate-specific antigen-detected early prostate cancer: a nationwide population-based cohort study from PCBaSe Sweden. Eur Urol. 2010 Mar;57(3):390-5.

Van Hemelrijck M, Wigertz A, Sandin F, Garmo H, Hellström K, Fransson P, et al. Cohort Profile: The National Prostate Cancer Register (NPCR) of Sweden and Prostate Cancer data Base Sweden (PCBaSe) 2.0. Int J Epid. 2012 Mar 28. In Press.

Thorstenson A, Bratt O, Akre O, Hellborg H, Holmberg L, Lambe M, et al. Incidence of fractures causing hospitalisation in prostate cancer patients: Results from the population-based PCBaSe Sweden. Eur J Cancer. 2012 Feb 29. In Press.

Jansson KF, Akre O, Garmo H, Bill-Axelson A, Adolfsson J, Stattin P, Bratt O. Concordance of Tumor Differentiation Among Brothers with Prostate Cancer. Eur Urol. 2012 Feb 24. In Press.

Van Hemelrijck M, Garmo H, Holmberg L, Stattin P, Adolfsson J. Multiple Events of Fractures and Cardiovascular and Thromboembolic Disease Following Prostate Cancer Diagnosis: Results From the Population-Based PCBaSe Sweden. Eur J Cancer. 2012 Apr;61(4):690-700.

Berglund A, Garmo H, Robinson D, Tishelman C, Holmberg L, Bratt O, et al. Differences according to socioeconomic status in the management and mortality in men with high risk prostate cancer. Eur J Cancer. 2012 Jan;48(1):75-84.

Robinson D, Garmo H, Lindahl B, Van Hemelrijck M, Adolfsson J, Bratt O, et al. Ischemic Heart Disease and Stroke Before and During Endocrine Treatment for Prostate Cancer in PCBaSe Sweden. Int J Cancer. 2012 Jan 15;130(2):478-87.

Akre O, Garmo H, Adolfsson J, Lambe M, Bratt O, Stattin P. Mortality Among Men with Locally Advanced Prostate Cancer Managed with Noncurative Intent: A Nationwide Study in PCBaSe Sweden. Eur Urol. 2011 Sep;60(3);554-63.

Bill-Axelson A, Garmo H, Nyberg U, Lambe M, Bratt O, Stattin P, et al. Psychiatric treatment in men with prostate cancer - Results from a Nation-wide, population-based cohort study from PCBaSe Sweden. Eur J Cancer. 2011 Sep;47(14):2195-201.

Berglund A, Garmo H, Tishelman C, Holmberg L, Stattin P, Lambe M. Comorbidity, Treatment and Mortality: A Population Based Cohort Study of Prostate Cancer in PCBaSe Sweden. J Urol. 2011 Mar;185(3):833-9.

Bratt O, Garmo H, Adolfsson J, Bill-Axelson A, Holmberg L, Lambe M, et al. Effects of prostate-specific antigen testing on familial prostate cancer risk estimates. J Natl Cancer Inst. 2010 Sep 8;102(17):1336-43.

Van Hemelrijck M, Garmo H, Holmberg L, Ingelsson E, Bratt O, Bill-Axelson A, et al. Absolute and Relative Risk of Cardiovascular Disease in Men With Prostate Cancer: Results From the Population-Based PCBaSe Sweden. J Clin Oncol. 2010 Jul 20;28(21):3448-56.

Stattin P, Holmberg E, Johansson JE, Holmberg L, Adolfsson J, Hugosson J. Outcomes in localized prostate cancer: National Prostate Cancer Register of Sweden follow-up study. J Natl Cancer Inst. 2010 Jul 7;102(13):950-8.

Stattin P, Holmberg E, Johansson JE, Holmberg L, Adolfsson J, Hugosson J. Outcomes in localized prostate cancer: National Prostate Cancer Register of Sweden follow-up study. J Natl Cancer Inst. 2010 Jul 7;102(13):950-8.

If you have published anything based on these data, please notify us with a reference to your publication(s).

PcBaSe Sweden

Data format / data structure:

Numeric

Data collection:

Time period(s) for data collection: 1996-01-01 — 2009-12-31

Data collector: Umeå University, Department of Surgical and Perioperative Sciences

Source of the data: Registers/Records/Accounts: Medical/Clinical

Number of individuals/objects:

110000