Creator/Principal investigator(s)
Nancy Pedersen
- Karolinska Institutet, Department of Medical Epidemiology and Biostatistics
Description
The Swedish Adoption/Twin Study of Aging (SATSA) is a longitudinal study where the twin design and the inclusion of twins reared apart makes it possible to study the importance of genetic and environmental factors that may underlie differing aging outcomes. The baseline population consists of all twins from the Swedish Twin Registry (STR) who had been reared apart (TRA), i.e. separated before age of 11 and reared apart, and a control sample of twins reared together (TRT) matched on sex, date of birth, and county of birth.
SATSA started with a survey in 1984 where a questionnaire was sent to all surviving individuals (n=2845). Out of these 2018 responded (71%). Questionnaire data have been collected at nine waves with approximately three-year intervals over a total of 28 years.
A subset of the individuals in SATSA where both twins still were alive, >50 years of age, and had responded to the initial questionnaire, were included for an in-person testing (IPT), which involved cognitive tests and clinical examinations. The first IPT was conducted in 1986-88 where 645 individuals (303 pairs) were
Language
English
Swedish
Research principal
Responsible department/unit
Karolinska Institutet, Department of Medical Epidemiology and BiostatisticsData contains personal data
Yes
Sensitive personal data
Yes
Type of personal data
Pseudonymised data
Code key exists
Yes
Ethics Review
Other - Ref. 80:80
Forskningsetikkommittén vid Karolinska Institutet
Other - Ref. 98:319
Forskningsetikkommittén vid Karolinska Institutet
Other - Ref. 84:61
Forskningsetikkommittén vid Karolinska Institutet
Other - Ref. 93:226
Forskningsetikkommittén vid Karolinska Institutet
Other - Ref. 2010/657-31/3
Forskningsetikkommittén vid Karolinska Institutet
Unit of analysis
Population
All twins in the Swedish Twin Registry who were separated at an early age and reared apart and a control sample of twins reared together
Study design
Observational study
Cohort study
Cohort study: Prospective
Sampling procedure
Time period(s) investigated
1987 – 2014
Biobank is connected to the study
The study has collected samples/material which are stored in a scientific collection or biobank
Scientific collection or biobank name: SATSA
Type(s) of sample: Blood tests
Geographic spread
Geographic location: Sweden
Research area
Medical and Health Sciences, Geriatrics, Psychology (excluding Applied Psychology)
(The Swedish standard of fields of research 2011)
Keywords
aged, ageing, epidemiologic studies, dementia, life style, geriatrics, longitudinal studies, socioeconomic factors, surveys and questionnaires, public health, genes, cognition, environment, personality, registries, social environment, heredity, twin study, human health and safety, near- national e-infrastructure for aging research, self-report
Finkel, D., & Pedersen, N. (2004). Processing speed and longitudinal trajectories of change for cognitive abilities: The Swedish Adoption/Twin Study of Aging. In AGING NEUROPSYCHOLOGY AND COGNITION (Vol. 11, Issues 2–3, pp. 325–345). https://doi.org/10.1080/13825580490511152
DOI:
https://doi.org/10.1080/13825580490511152
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Contact
Associated documentation
Description
The SATSA questionnaires assessed physical and mental health status; selected personality dimensions; activities of daily living; health-related behaviors of smoking, alcohol consumption and legal drug use; early rearing environment, and the adult working, family and social environments. For the TRA subjects, circumstances of separation were also explored.
The IPT included interviews, a health examination including blood pressure and lung function, blood sampling, and tests on functional capaci
Citation
Data format / data structure
Numeric
Creator/Principal investigator(s)
Nancy Pedersen
- Karolinska Institutet, Department of Medical Epidemiology and Biostatistics
Time period(s) investigated
1984 – 2014
Variables
2274
Response rate/participation rate
71%
Response rate Q1