Betula - aging, memory and dementia

SND-ID: EXT 0045

This study is part of the collection NEAR - National E-Infrastructure for Aging Research in Sweden

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Description

The Betula Project is a longitudinal study of aging, memory and dementia. Data was collected between 1988 - 2014.

Then the study began with including 1000 randomly selected individs from the Umeå municipality in the age groups 20, 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 years. It was 100 in each age cohort, and the gender distribution was similar to the population with about as many men as women in the younger age groups, and about twice as many women as men in the age groups 70 and over. Five years later, wo more sample were included. The group has been monitored every five years: 1993, 1998, 2003, 2008 and 2013. For each sample, each participant completed a thorough physical examination with blood tests of a nurse and a careful examination of a memory tester. There are data collected from approximately 4,700 participants. On each occasion, data for about 2000 variables were collected for each participant, which includes data on demographics, health, illness, medication, social and cognitive factors.

The Betula project has received funding for research infrastructures (large databases) f

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Research principal, contributors, and funding

Research principal

Umeå University

Responsible department/unit

Department of Integrative Medical Biology (IMB)

Protection and ethical review

Data contains personal data

Yes

Code key exists

Yes

Method and time period

Unit of analysis

Population

Indivduals in agegroups between 25-80 living in Umeå county

Time Method

Sampling procedure

Probability: Stratified
1000 individuals in age groups 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75 and 80 were randomly selected (sample 1, S1). There were 100 individuals i each age cohort, the gender distribution reflected the gender distribution in the population ie about as many men as women in the younger age groups and about twice as many women as men from age group 70 and above (test occasion 1, T1) In T2, five years later, two new samples were added to the group, S2 and S3, randomly selected från Umeå county.

Time period(s) investigated

1988 – 2014

Geographic coverage

Geographic spread

Geographic location: Sweden

Geographic description: Umeå county

Publications

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Danielsson, H., Henry, L.A., Rönnberg, J., & Nilsson, L.-G. (2010). Selective problems in executive function in adults with ID: The Betula Database. Journal of Applied Research in Intellectual Disabilities, 23, 438-458.

Van Gestel, S., Forsgren, T., Verheyen, G., Lundberg, M., Nilsson, L.-G., Van Broeckhoven, C., Raeymaekers, P., & Adolfsson, R. (2002). The use of extremely high and low scoring individuals on temperament scales in genetic analyses: A power calculation. American Journal of Medical Genetics, 81, 487-487.

Naghavi, H.R., Lind, J., Nilsson, L.-G., Adolfsson, R., & Nyberg, L. (2009). Personality traits predict response to novel and familiar stimuli in the hippocampal region. Psychiatry Research: Neuroimaging, 173, 94-99

de Frias, C.M., Marklund, P., Eriksson, E., Larsson, A., Öhman, L., Annerbrink, K., Bäckman, L., Nilsson, L.-G., & Nyberg, L. (2010). Influence of COMT gene polymorphism on fMRI-assessed sustained and transient activity during a working-memory task. Journal of Cognitive Neuroscience, 22, 1614-1622.

Wikgren, M., Maripuu, M., Karlsson, T., Nordfjäll, K., Bergdahl, J., Hultdin, J., Del-Favero, J., Roos, G., Nilsson, L.-G., Adolfsson, R., & Norrback, K.-F. (2012). Short telomeres in depression and the general population are associated with hypocortisolemic state. Biological Psychiatry, 71, 294-300. Doi: 10.1016/j.biopsych.2011.09.015.

Molander, B., Andersson, R., Forsgren, L., Hilmgren, S., Marklund, P., & Nilsson, L.-G. (2000). Subjective health as a function of age and time of measurement. International Journal of Psychology, 35, 367.

Chotai, J., Smedh, K., Johansson, C., Nilsson, L.-G., & Adolfsson, R. (2004). An epidemiological study on gender differences in self-reported seasonal changes in mood and behaviour in a general population of northern Sweden. Nordic Journal of Psychiatry, 58, 429-437.

Van Gestel, S., Forsgren, T., Claes, S., Del-Avero, J., van Duijn, C. M., Sluijs, S., Nilsson, L.-G., Adolfsson, R., & Van Broeckhoven, C. (2002). Epistatic effect of genes from the dopamine and serotonine systems on the temperament traits of novelty seeking and harm avoidance. Molecular Psychiatry, 7, 448-450.

Rönnlund, M., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2003). Recall of subject-performed tasks, verbal tasks, and cognitive activities across the adult life span: Parallel age-related deficits. Aging, Neuropsychology and Cognition, 10, 182-201.

Nilsson, L.-G., Sternäng, O., Rönnlund, M., & Nyberg, L. (2009). Challenging the notion of an early-onset of cognitive aging. Neurobiology of Aging, 30, 521-524.

Nilsson, L.-G., & Söderlund, H. (2001). Aging, cognition, and health. In M. Naveh-Benjamin, M. Moscovitch, & H.L. Roediger, III (Eds.), Perspectives on human memory and cognitive aging: Essays in honor of Fergus Craik, pp. 253-264. London: Psychology Press.

Launer, L., Oudkerk, M., Nilsson, L.-G., Alperovitch, A., Berger, K., Breteler, M.M.B., Fuhrer, R., Giampaoli, S., Nissinen, A., Pajak, A., Sans, S., Schmidt, R., & Hofman, A. (2000). CASCADE: A European collaborative study on vascular determinants of brain lesion: Study design and objectives. Neuroepidemiology, 19, 113-120.

Dixon, R.A., Bäckman., L., & Nilsson, L.-G. (2004). New frontiers in cognitive aging. New York: Oxford University Press

Yonker, J.E., Nilsson, L.-G., Herlitz, A., & Anthenelli, R. (2005). Sex differences in episodic memory as a function of alcohol consumption. Alcohol and Alcoholism, 40, 201-207.

Sundström, A., Nilsson, L.-G., & Nyberg, L. (2002). Cognitive performance before and after mild head injury. Journal of cognitive neuroscience, B77 (suppl s), 60-60.

Kormi-Nouri, R., Shojaei, R.-S., Moniri, S., Gholami, A.-R., Moradi, A.-R., Akbari-Zardkhaneh, S., & Nilsson, L.-G. (2008). The effect of childhood bilingualism on episodic and semantic memory tasks. Scandinavian Journal of Psychology, 49(2), 93-109.

Mousavi-Nasab, S.-M. H., Kormi-Nouri, R., Sundström, A., & Nilsson, L.-G. (2012) The effects of marital status on episodic and semantic memory in healthy middle-aged and old individuals. Scandinavian Journal of Psychology, 53, 1-8. Doi: 10.1111/j.1467-9450.2011.00926.x

Nyberg, L., Andersson, M., Forsgren, L., Jakobsson-Mo, S., Larsson, A., Marklund, P., Nilsson, L.-G., Riklund, K., & Bäckman, L- (2009). Striatal dopamine D2 binding is related to frontal BOLD response during updating of long-term memory representations. NeuroImage, 46, 1194-1199.

Erngrund, K., Mäntylä, T., & Rönnlund, M. (1996). Acting or listening: Adult age differences in source recall of enacted and nonenacted statements. Journal of Adult Development, 3, 217-232

Yonker, J.E., Adolfsson, R., Eriksson, E., Hellstrand, M., Nilsson, L.-G., & Herlitz, A. (2006). Hormone replacement therapy improves episodic memory performance in healthy postmenopausal women. Aging, Neuropsychology, and Cognition, 13, 291-307.

Schalling, M., Johansson, C., Willeit, M., Smedh, C., Ekholm, J., Paunio, T., Lichterman, D., Praschak-Rieder, N., neumeister, A., Nilsson, L.-G., Kasper, S., Peltonen, L., Levitan, R., Del Favero, J., masellis, M., Basile, V., Zill, P., Bondy, B., Van Broeckhoven, C., Lam, R., Adolfsson, R., & Partonen, T. (2002). Circadian clock related polymorphisms and the serotonin transporter promoter in seasonal affective disorder and seasonality. American Journal of medical Genetics, 114, 727-728.

Olofsson, J., Rönnlund, M., Nordin, S., Nyberg, L., Nilsson, L.-G., & Larsson, M. (2009). Odor identification deficit as a predictor of five-year global cognitive change: Interactive effects with age and ApoE-?4. Behavior Genetics, 39, 496-503.

Nilsson, L.-G. (2000). Can genes teach us anything about memory? In E. Tulving (Ed.), Memory, consciousness, and the brain: The Tallinn conference, pp. 28-37. Philadelphia: Psychology Press.

Bergdahl, J., Larsson, A., Nilsson, L.-G., Riklund Åhlström, K., & Nyberg, L. (2005). Treatment of chronic stress in employees: Subjective, cognitive, and neural correlates. Scandinavian Journal of Psychology, 46, 395-402.

Lövdén, M., Rönnlund, M., Söderlund, H., Persson, J., Hasnoot, A., & Nilsson, L.-G. (2000). Cross-sectional and longitudinal patterns in explicit and implicit memory: Evidence from the Betula Study. International Journal of Psychology, 35, 366.

von Essen, J.D., & Nilsson, L.-G. (2003). Memory effects of motor activation in subject performed tasks and sign language. Psychological Bulletin & Review, 10, 445-449.

Lövdén, M., Bergman, L., Adolfsson, R., Lindenberger, U., & Nilsson, L.-G. (2005). Studying individual aging in an interindividual context: Typical paths of age-related, dementia-related, and mortality-related cognitive development in old age. Psychology and Aging, 20, 303-316.

Nilsson, L.-G., & Rönnberg, J. (2006). Learning and memory. In K. Pawlik & G. d'Ydewalle (Eds.), Psychological concepts: An international historical perspective, pp. 223-236. Hove, UK: Psychology Press.

Erngrund, K., Nilsson, L.-G., & Mäntyla, T. (1996). Adult age differences in source memory: A population based study. Journal of Gerontology: Psychological Scieneces, 51B, P335-P345.

Markowitsch, H.J., & Nilsson, L.-G. (1999). Memory and brain: Unresolved issues. In L.-G. Nilsson & H.J. Markowitsch (Eds.), Cognitive neuroscience of memory, pp.271-276. Göttingen: Hogrefe & Huber Publishers.

Rönnlund, M., & Nilsson, L.-G. (2006). Adult life-span patterns in WAIS block design performance: Cross-sectional versus longitudinal age gradients and relations to demographic predictors. Intelligence, 34, 63-78.

Söderlund, H., Nilsson, L.-G., Berger, K., Breteler, M.M., de Ridder, M., Dufouil, C., Fuhrer, R., Giampaoli, S., Hofman, A., Pajak, A., Sans, S., Schmidt, R., & Launer, L. (2006). Cerebral changes on MRI and cognitive function: The CASCADE Study. Neurobiology of Aging, 27, 16-23.

Nilsson, L.-G. (2010). The Betula Study: Memory, ageing, health and dementia in Sweden. Public Service Review: European Union, 19, 130-131.

Persson, J., Lind, J., Larsson, A., Ingvar, M., Sleegers, K., Van Broeckhoven, C., Adolfsson, R., Nilsson, L.-G., & Nyberg, L. (2008). Altered deactivation in individuals with genetic risk for Alzheimer's disease. Neuropsychologia, 46, 1679-1687.

Van Den Eede, F., Venken, T., Del-Favero, J., Norrback, K.-F., Souery, D., Nilsson, L.-G., Van den Bossche, B., Houlstijn, W., Sabbe, B. G. C., Cosyns, P., Mendlewicz, J., Adolfsson, R., Van Broeckhoven, C., & Claes, S. J. (2007). Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in recurrent major depressive disorder. Psychiatry Research, 153, 17-25.

Lekander, M., von Essen, J., Schultzberg, M., Nixon Andreasson, A., Garlind, A., Hansson, L.-O., & Nilsson, L.-g. (2011). Cytokines and memory across the mature life span of women. Scandinavian Journal of Psychology, 52, 229-235. Doi: 10.1111/j.1467-9450.2010.00865.x.

Kompus, K., Westerhausen, R., Nilsson, L.-G., Hugdahl, K., Jongstra, S., Berglund, A., Arver, S., & Savic, I. (2011). Deficits in inhibitory executive functions in Klinefelter (47, XXY) syndrome. Psychiatry Research, 189, 135-140. Doi: 10.1016/jpsychres.201102.028.

Bergman, O., Westberg, L., Nilsson, L.-G., Adolfsson, R., & Eriksson, E. (2010). Preliminary evidence that polymorphisms in dopamine-related transcription factors LMX1A, LMX1B and PITX3 are associated with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34, 1094-1097.

Rönnberg, J., Danielsson, H., Rudner, M., Arlinger, S., Sternäng, O., Wahlin, Å., & Nilsson, L.-G. (2011). Hearing loss is negatively related to episodic and semantic long-term memory but not to short-term memory. Journal of Speech, Language, and Hearing Research, 54, 705-726. Doi: 10.1044/1092-4388(2010/09-0088).

Nilsson, L.-G. (2002). The role of genetics in understanding memory. In C. Von Euler & E. Hjelmquist (Eds.), Dyslexia and literacy: A tribute to Ingvar Lundberg, pp.192-205. London: Whurr Publishers.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Edvardsson, H, Nyberg, L., & Van Broeckhoven, C. (2000). Normal memory development and the role of apolipoproteinE: The Betula study. International Journal of Psychology, 35, 366.

Holmgren, S., Molander, B., & Nilsson, L.-G. (2006). Intelligence in adult age: Effects of sibship size and birth order. European Journal of Cognitive Psychology, 18, 138-158.

van Dijk, E.J., Breteler, M.M.B., Schmidt, R., Berger, K., Nilsson, L.-G., Ouderk, M., Pajak, A., Sans, S., de Ridder, M., Dufoil, C., Fuhrer, R., Giampaoli, S., Launer, L.J., & Hofman, A. (2004). The association between blood pressure, hypertension and cerebral white matter lesions: The CASCADE Study. Hypertension, 44, 625-630.

Nyberg, L., Petersson, K.M., Nilsson, L.-G., Sandblom, J., Åberg, C., & Ingvar, M. (2001). Reactivation of Motor Brain Areas during Explicit Memory for Actions. NeuroImage, 14, 521-528.

Nilsson, L.-G. (2005). Nilsson, L.-G. (2005). Aging and brain degeneration. European Neuropsycho-pharmacology, 15, S101-S101., 15, S101-S101.

Moens, L.N., De Rijk, P., Reumers, J., Van den Bossche, M.J.A., Glassee, W., De Zutter, S., Lenaerts, A.S., Nordin, A., Nilsson, L.-G., Castello, I.M., Norrback, K.F., Goossens, D., Van Steen, K., Adolfsson, R., & Del-Favero, J. (2011). Sequencing of DISC1 patheway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population. PlosONE, 6. Doi: 10.1371/journal.pone.0023450.

Rönnlund, M., Mäntylä, T., & Nilsson, L.-G. (2008). The prospective and retrospective memory questionnaire (PRMQ): Factorial structure, relations to global subjective memory ratings, and Swedish norms. Scandinavian Journal of Psychology, 49, 11-18.

de Frias, C.M., Nilsson, L.-G., & Herlitz, A. (2006). Sex differences in cognition are stable over a 10-year period in adulthood and old age. Aging, Neuropsychology and Cognition, 13, 574-587.

Persson, J., Nyberg, L., Lind, J., Larssson A., Nilsson, L.-G., Ingvar, M., & Buckner, R.L. (2006). Structure -Function correlates of cognitive decline in aging. Cerebral Cortex, 16, 907-915.

Magnussen, S., Andersson, J., Cornoldi, C., De Bini, R., Endestad, T., Goodman, G.S., Helstrup, T., Koriat, A., Larsson, M., Melinder, A., Nilsson, L.-G., Rönnberg, J., & Zimmer, H. (2006). What people believe about memory. Memory, 14, 595-613.

Nilsson, L.-G. (1999). Is cognitive functioning mediaded by health and life-style variables? Psicologia Italiana, 123, 23-25.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Nyberg, L., Small, B.J., & Van Broeckhoven, C. (2006). The influence of APOE status on episodic and semantic memory: Data from a population-based study. Neuropsychology, 20, 645-657.

Rolandsson, O., Backeström, A., Eriksson, S., Hallmans, G., & Nilsson, L.-G. (2008). Increased glucose levels are associated with episodic memory in nondiabetic women. Diabetes, 57, 440-443.

Kask, K., Bäckström, T., Nilsson, L.-G., & Sundström-Poromaa, I. (2008). Allopregnanolone impairs episodic memory in healthy women. Psychpharmacology, 199(2), 161-168.

Nilsson, L.-G., Sikström, C., Adolfsson, R., Erngrund, K., Nylander, P.-O., Beckman, L. (1996). Genetic markers with high versus low scoring on episodic memory tasks. Behavior Genetics, 26, 555-562.

Kauppi, K., Nilsson, L.-G., Adolfsson, R., Eriksson, E., & Nyberg, L. (2011). KIBRA polymorphism is related to enhanced memory and elevated hippocampal processing. Journal of Neuroscience, 40, 14218-14222. Doi: 10.1523/jneurosci.3292-11.2011.

Nyberg, L., Bäckman, L., Erngrund, K., Olofsson, U., & Nilsson, L.-G. (1996). Age differences in episodic memory, semantic memory, and priming: Relationships to biological, demographic, and psychometric variables. Journal of Gerontology: Psychological Sciences, 51B, P234-240.

Yonker, J.E., Eriksson, E., Nilsson, L.-G., & Herlitz, A. (2006). Negative effects of testosterone on visuospatial ability in 35 to 80 year old men. Cortex, 42 376-386.

Hill, R. D., Nilsson, L.-G., Nyberg, L., & Bäckman, L. (2003). Cigarette smoking as a predictor of cognitive performance in healthy Swedish adults from the Betula prospective cohort study of aging, memory and health. Age and Aging, 32, 1-4.

Sundström, A., Nilsson, L.-G., Cruts, M., Adolfsson, R., Van Broeckhoven, C., & Nyberg, L. (2007). Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE-?4 allele. International Psychgeriatrics, 19, 159-165.

Nilsson, L.-G. (1996). Memory and health. In T. Niit & A. Baltin (Eds.), Identity, freedom, values and memory, pp. 49-68. Tallinn: Union of Estonian Psychologists.

Karlsson, T., Johansson, I., Adolfsson, R., Nilsson, L.-G., & Dubuc, S. (2003). Recognition memory in Alzheimer's disease. A demonstration of a remarkable memory capacity in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 15, 6-9.

Hedner, M., Nilsson, L.-G., Olofsson, J.K., Bergman, O., Eriksson, E., Nyberg, L., & Larsson, M. (2011). Age-related olfactory decline is associated with the val66met polymorphism: Evidence from a population-based study. Frontiers of Cognitive Aging: Neoroscience. Doi: 10.3389/fnagi.2010.00024.

Mäntylä, T., & Nilsson, L.-G. (1997). Remembering to remember in adulthood: A population-based study on aging and prospective memory, manuscript. Aging, Neuropsychology, & Cognition, 4, 81-92.

Nilsson, L.-G., Bäckman, L., Cruts, M, Edvardsson, H., Nyberg, L., Van Broeckhoven, C., Adolfsson, R. (2002). Memory development in adulthood and old age: The Betula prospective cohort study. In P. Graf & N. Ohta (Eds.), Lifespan Development of Human Memory. Philadelphia: The MIT Press

Nilsson, L.-G., & de Frias, C.M. (2006). The effect of genetics and vascular health on memory functioning: The Betula Study. In Q. Jing, H.-C. Chen, G. d'Ydewalle, M.R. Rosenzweig, H. Zhang, & K. Zhang (Eds.), Proceedings of the 28th International Congress of Psychology, pp. 113-128. London: Psychology Press.

Nilsson, L.-G., Adolfsson, R., Bucht, G., Bäckman, L., & Winblad, B. (1992). Betula: En prospektiv undersökning om minnesfunktion och hälsa. Socialmedicinsk Tidskrift, 69, 193-198.

Alaerts, M., Ceulemans, S., Forero, D., Moens, L.N., De Zutter, S., Heyman, L., Lenaerts, A.S., Norrback, K.F., Goossens, D., De Rijk, P., Nilsson, L.-G., Adolfsson, R., & Del-Favero, J. (2009). Detailed analysis of the serotonin transporter gene (SLC6A4) shows no association with bipolar disorder in the Northern Swedish population. American Journal of Medical Genetics: Neuropsychiatric Genetics, 150B, 585-592.

Yonker, J., Nilsson, L.-G., Staaf, E., & Herlitz, A. (2000). Estradiol does not contribute significantly to episodic memory differences in men and women. International Journal of Psychology, 35, 368.

Nyberg., L., Maitland, S., Rönnlund, M., Bäckman, L., Dixon, R., Wahlin, Å., & Nilsson, L.-G. (2000). The structure of declarative memory: Competing theoretical models and measurement equivalence. International Journal of Psychology, 35, 365.

Maitland, S., Bäckman, L., Dixon, R., Hultsch, D., Nilsson, L.-G., & Wahlin, Å. (2000). Health-gender relationships: Tests of equivalence across cultures. International Journal of Psychology, 35, 367.

Sternäng, O., Wahlin, Å., & Nilsson, L.- G. (2008). Examination of the processing speed account in a population-based longitudinal study with narrow age cohort design. Scandinavian Journal of Psychology, 49(5), 419-428

Vestergren, P., Rönnlund, M., Nyberg, L., & Nilsson, L.-G. (2011). Development of the Cognitive Dysfunction Questionnaire (CDQ) in a population based sample. Scandinavian Journal of Psychology, 52, 218-228. Doi: 10.1111/j.1467-9450.2010.00861.x.

de Frias, C.M., Annerbrink, K., Westberg, L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2005). Catechol O-Methyltransferase Val155Met polymorphism is associated with Cognitive performance in nondemented adults. Journal of Cognitive Neuroscience, 17, 1018-1025.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Nyberg, L., Small, B.,J., & Van Broeckhoven, C. (2004). Impairment of episodic memory and word fluency in carriers of the APOE-?4 allele. Behavior Genetics, 34, 654-654.

Ballesteros, S., Nilsson, L.-G., & Lamaire, P. (2009). Ageing, cognition and neuroscience: An introduction. European Journal of Cognitive Psychology, 21, 161-175.

Hultdin, J., Wahlin, Å., Bäckman, L., Edvardsson, H., Adolfsson, R., & Nilsson, L.-G. (2000). Vitamin B12, folate and homocysteine as markers of cognitive defects: The Betula project. International Journal of Psychology, 35, 366.

Johansson, C., Willeit, M., Levitan, R., Partonen, T., Smedh, C., Praschak-Rieder, N., Neumeister, A., Masellis, M., Basile, V., Zill, P., Bondy, B., Paunio, T., Kasper, S., Van Broeckhoven, C., Nilsson, L.-G., Lam, R., Schalling, M., & Adolfsson, R. (2003). The serotonin transporter promoter repeat length polymorphism, seasonal affective disorder and seasonality. Psychological Medicine, 33, 785-792.

Malmberg, G., Nilsson, L.-G., & Weinehall, L. (2010). Longitudinal data for interdiscipinary aging research. Scandinavian Journal of Public Health, 38, 761-767.

Nilsson, L.-G., Bäckman, L., Nyberg, L., Erngrund, K., Adolfsson, R., Bucht, G., Karlsson, S., Widing, G., & Wilblad, B. (1997). The Betula prospective cohort study: Memory, health, and aging. Aging, Neuropsychology and Cognition, 4, 1-32.

Söderlund, H., Nyberg, L., Smedberg-Åman, G., Sundbaum-Åström, M., Sundström, I. -M., Widing, M., & Nilsson, L.-G. (2000). Effects of white matter lesions on cognition: Swedish CASCADE data. International Journal of Psychology, 35, 367.

Nilsson, L.-G. (1999). Memory and aging: Basic dissociations between episodic and semantic memory. In W.Hacker & M Rinck (Eds.), Zukunft gestalten, pp. 103-108. Paps Science Publishers.

Melke, J., Westberg, L., Nilsson, S., Landén, M., Söderström, H., Baghaei, F., Rosmond, R., Holm, G., Björntorp, P., Nilsson, L.-G., Adolfsson, R., & Eriksson. E., (2003). A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women. Archives of General Psychiatry, 60, 1017-1023.

Nilsson, L.-G. (2004). The genetic contribution to individual differences in memory function. International Journal of Psychology, 39, 33-33.

Hedner, M., Nilsson, L.-G., Olofsson, J. et al. (2008). The BDNF Val66Met polymorphism influences olfactory processing. International Journal of Psychology, 43, 275-276.

Wikgren, M., Karlsson, T., Nilbrink, T., Nordfjäll, K., Hultdin, J., Sleegers, K., Van Broeckhoven, C., Nyberg, L., Roos, G., Nilsson, L.-G., Adolfsson, R., & Norrback, K.-F. (2012). APOE e4 is associated with longer telomeres, and longer telomeres among e4 carriers predicts worse episodic memory. Neurobiology of Aging, 33, 335-344. Doi: 10.1016/j.neurobiolaging.2010.03.004.

Nyberg, L., Nilsson, L.-G., Olofsson, U., & Bäckman, L. (1997). Aging and attentional capacity: Memory retrieval is more demanding for older than for younger adults. Experimental Aging Research, 23, 137-143.

Yonker, J.E., Liu, W., Nilsson, L.-G., & Anthenelli, R.M. (2004). Influence of alcohol consumption on cognitive performance in age-and education-matched women. Alcoholism Clinical and Experimental Research, 28, 148A.

Wahlin, Å., Bäckman, L., Hultdin, J., Adolfsson, R., & Nilsson, L.-G. (2002). Reference values of serum levels of vitamin B12 and folic acid in a populationbased sample of adults between 35 and 80 years of age. Journal of Public Health and Nutrition, 5, 505-511.

Söderlund, H., Nyberg, L., Adolfsson, R., Nilsson, L.-G., & Launer, L. (2003). High prevalence of white-matter hyperintensities in normal aging: Relation to blood pressure and cognition. Cortex, 39, 1093-1105.

Backeström, A., Eriksson, S., Nilsson, L.-G., Nyberg, L., Olsson, T., & Rolandsson, O. (2010). Glucose metabolism and cognitive dysfunction. Diabeologia, 53, 730.

de Frias, C. M., Annerbrink, K., Westberg. L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2004). COMT gene polymorphism is associated with declarative memory in adulthood and old age. Behavior Genetics, 34, 533-539.

Rönnlund, M., & Nilsson, L.-G. (2006). The Betula Study: Reliabilities and long-term stabilities of memory test performances over the adult lifespan. Baltic Journal of Psychology, 7, 6-14.

Habib, R., Nyberg, L., & Nilsson, L.-G. (2007). Cognitive and non-cognitive factors contributing to the longitudinal identification of successful older adults in the Betula study. Aging, Neuropsychology and Cognition, 14, 257-273.

Chotai, J., Forsgren, T., Nilsson, L.-G., & Adolfsson, R. (2001). Season of birth variation in the temperament and character inventory of personality in a general population. Neuropsychobiology, 44, 19-26.

Eriksson, D., Nilsson, L.-G., Rönnlund, M., & Sundström, A. (2010). Effects of perceived long-term stress on health and memory functioning. Abstracts of the Psychonomic Society, 15, 78-78.

Maitland, S.B., Nyberg, L., Bäckman, L., Nilsson, L.-G., & Adolfsson, R. (2009). On the structure of personality: Are there separate temperament and character factors. Personality and Individual Differences, 47, 180-184.

Alaerts, M., Ceulemans, S., Forero, D., Moens, L.N., De Zutter, S., Heyman, L., Lenaerts, A.S., Norrback, K.F., De Rijk, P., Nilsson, L.-G., Goossens, D., Adolfsson, R., & Del-Favero, J. (2009). Support for NRG1 as a susceptibility factor for schizophrenia in a Northern Swedish isoated population. Archives of General Psychiatry, 66, 828-828

Persson, J., Lind, J., Larsson, A., Crutz, M., Van Broeckhoven, C., Adolfsson, R., Nilsson, L.-G., & Nyberg, L. (2006). Altered brain white-matter integrity in non-demented carriers of the APOE-?4 allele: A risk for Alzheimer's disease. Neurology, 66, 1029-1033.

Nilsson, L.-G., Nyberg, L., & Bäckman, L. (2002). Genetic variation in memory functioning. Neuroscience and Biobehavioral Review, 26, 841-848.

Nilsson, L.-G., Nyberg, L., Klingberg, T., Åberg, C., Persson, J., & Roland, P. (2000). Activity in motor areas while remembering action events. NeuroReport, 11, 2199-2201.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Molander, B., Nyberg, L., Smedberg-Åman, G, Widing, M., Söderlund, A. -L., Säfström, B., & Norin, E. (2000). The Betula study: Objectives, Assessment, and Design. International Journal of Psychology, 35, 234.

Lövdén, M., Rönnlund, M., & Nilsson, L.-G. (2002). Remembering and knowing in adulthood: Effects of enacted encoding and relations to processing speed. Aging, Neuropsychology and Cognition, 9, 184-200.

Pickard B.S., Van Den Bossche M.J., Malloy M.P., Johnstone M., Lenaerts A.S., Nordin A., Goossens D., St Clair D., Muir W.J., Nilsson L.-G., Sabbe B., Adolfsson R., Blackwood D.H., & Del-Favero J. (in press). Multiplex amplicon quantification screening the ABCA13 gene for copy number variation in schizophrenia and bipolar disorder. Psychiatric Genetics. 2012 Mar 1. [Epub ahead of print]

Nilsson, L.-G. (2004). Memory and genes- is there an association? In W. Östreng (Ed.), Synergies. Oslo: Centre for Advanced Study.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., Cruts, M., Edvardsson, H., Nyberg, L., & Van Broeckhoven, C. (2000).The roles of apolipoproteinE and memory as predictors for dementia in a nondemented population: The Betula study. International Journal of Psychology, 35, 366.

Rönnlund, M., Bäckman, L., Nyberg, L., Lövdén, M., & Nilsson, L.-G. (2000). Five-year changes in recall across levels of support: Parallel age-related deficits. International Journal of Psychology, 35, 366.

Ericsson, K., Winblad, B., & Nilsson, L.-G. (2001). Human-figure-drawing and memory functioning across the adult life span. Archives of Gerontology and Geriatrics, 32, 151-166.

Sundström, A., Nilsson, L.-G., Cruts, M., Adolfsson, R., Van Broeckhoven, C., & Nyberg, L. (2008). Fatigue before and after mild traumatic brain injury: Pre-post-injury comparisons in relation to ApolipoproteinE. Brain Injury, 1-6.

Söderlund, H., Nyberg, L., Nilsson, L.-G., & Launer, L. J. (2004). Cerebral atrophy as predictor of cognitive performance in healthy Swedish adults from the Betula prospective cohort study of aging, memory and health. Acta Neurologica Scandinavica, 109, 398-406.

Larsson, M., Lövdén, M., & Nilsson L.-G. (2003). Sex differences in recollective experience for olfactory and verbal information. Acta Psychologica, 112, 89-103.

Maitland, S. B., Herlitz, A., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2004). Selective sex differences in declarative memory. Memory and Cognition, 32, 1160-1169.

Nilsson, L.-G., Winblad, B., Adolfsson, R., Bucht, G., & Bäckman, L. (1992). Åldrande, minne och demens: Preliminära resultat från en prospektiv studie. Ingår i B. Pernow (Red.), Åldrande och åldersrelaterade sjukdomar. Stockholm: Gidlunds förlag.

Chotai, J., Smedh, K., Nilsson, L.-G., & Adolfsson, R. (2004). A dual vulnerability hypothesis for seasonal depression is supported by the seasonal pattern assessment questionnaire in relation to the temperament and character inventory of personality in a general population. Journal of Affective Disorders, 82, 61-70.

Lind, J., Ingvar, M., Persson, J., Cruts, M., Van Broeckhoven, C., Adolfsson, R., & Nilsson, L.-G. (2006). Parietal cortex activation predicts longitudinal memory decline in APOE-?4 carriers. NeuroReport, 17, 1683-1686.

Rönnlund, M., & Nilsson, L-G. (2009). Flynn effects on sub-factors of episodic and semantic memory: Parallel gains over time and the same set of determining factors. Neuropsychologia, 11, 2174-2188.

de Frias, C.M., Bunce, D., Wahlin, Å., Adolfsson, R., Sleegers, K., Cruts, M., Van Broeckhoven, C., & Nilsson, L.-G. (2008). Cholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults. Journal of Gerontology: Psychological Sciences, 62, P112-P118.

Wahlin, Å., Anstey, K., McDonald, S.W.S., Ahmed, S.M., Kivipelto, M., Kunnukattil, K.S.S., Mai, T.T., Nilsson, L.-G., Streatfield, P.K., van Boxtel, M.P., & Kabir, Z.N. (2008). The international network on public health and aging (INOPA): Introducing a life course perspective to the public health agenda. Journal of Cross-Cultural Gerontology, 23(1), 97-105.

de Frias, C. M., Lövdén, M., Lindenberger, U., & Nilsson, L.-G. (2007). Revisiting the dedifferention hypothesis with longitudinal multi-cohort data. Intelligence, 35, 381-392.

Nilsson, L.-G. (1993). Memory functions across the adult life span. Acta Psychologica Fennica, 8, 39-52.

Persson, J., Bringlöv, E., Nilsson L.-G., & Nyberg, L. (2004). The memory enhancing effects of ginseng and gingko biloba in healthy volunteers. Psychopharmacology, 172, 430-434.

Nilsson, L.-G., Van Broeckhoven. C., & Adolfsson, R. (2001). Genetic Contributions to Individual Differences in Memory Performance. European Psychologist, 6, 264-271.

Nilsson, L.-G., Adolfsson, R., Bäckman, L., de Frias, C., Molander. B., & Nyberg, L. (2004). Betula: A prospective cohort study on memory, health and aging. Aging, Neuropsychology and Cognition, 11, 134-1

Thilers, P.P., MacDonald, S.W., Nilsson, l.-G., & Herlitz, A. (2010). Accelerated postmenopausal cognitive decline is restricted to women ith normal BMI: Longitudinal evidence from the Betula project. Psychoneuroendocrinology, 35, 516-524.

Nilsson, L.-G., & Larsson, M. (2007). Objective and subjective memory function for men and women in adulthood and old age. In S. Magnussen & T. Helstrup (Eds.), Everyday memory, pp. 275-290. London: Psychology Press

Van Den Eede, F., Venken, T., Van Den Bogaert, A., Del-Favero, J., Norrback, K.-F., Nilsson, L.-G., Adolfsson, R., Van Broeckhoven, C., & Claes, S. J. (2007). Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in bipolar disorder. Psychiatry Genetics, 17, 304-307.

Sundström, A., Bergdahl, J., Nyberg, L., Bergdahl, M., & Nilsson, L.-G. (2010). Cognitive status in persons with Amalgam related complaints. Journal of Dental Research, 89, 1236-1240.

Maitland, S.B., Nyberg L., Herlitz A., Bäckman, L., & Nilsson L.-G. (2001). The structure of declarative memory: Sex differences and measurement equivalence in the Betula Study. The Gerontologist, 41, 223-224.

Herlitz, A., Bäckman, L., & Nilsson, L.-G. (1997). Gender differences in episodic memory. Memory & Cognition, 25, 801-811.

Han, B., & Nilsson, L.-G. (1997). A prospective cohort longitudinal research on memory, health and aging. Introduction of Betula project in Sweden. Psychological Science (China), 20, 272-273.

Bergdahl, M., Habib, R., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2007). Natural teeth and cognitive function in humans. Scandinavian Journal of Psychology, 48, 557-568.

Olofsson, J., Rönnlund, M., Nordin, S., et al. (2008). Odor identification impairment predicts cognitive decline and Alzheimer's disease. International Journal of Psychology, 43, 469-469.

Ceulemans, S., De Zutter, S., Heyrman, L., Norrback, K.-F., Nordin, A., Nilsson, L.-G., Adolfsson, R., Del-Favero, J., & Claes, S. (2011). Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated Swedish population. Bipolar Disorders, 13, 614-623. Doi: 10.1111/j.1399-5618.2011.00960.x.

Meyer, T. D., Hammelstein, P., Nilsson, L.-G., Skeppar, P., Adolfsson, R., & Angst, J. (2007). The Hypomania Checklist (HCL-32): Its factorial structure and association to indices of impairment in German and Swedish nonclinical samples. Comprehensive Psychiatry, 48, 79-87.

Nyberg, L., Salami, A., Andersson, M., Eriksson, J., Kalpouzos, G., Kauppi, K., Lind, J., Pudas, S., Persson, J., & Nilsson, L.-G. (2010) Longitudinal evidence for diminished frontal-cortex function in aging. PNAS, 107, 22682-22686. Doi: 10.1073/pnas.1012651108.

Annerbrink, K., de Frias, C.M., Westberg, L., Eriksson, E., Adolfsson, R., & Nilsson, L.-G. (2005). Catechol O-metyltransferase Val158Met polymorphism is associated with cognitive performance in nondemented adults. Nordic Journal of Psychiatry, 59, 405-405.

Nilsson, L.-G. (2011). Genetic and demographic factors related to successful aging. Frontiers in Human Neuroscience. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). Doi: 10.3389/conf.fnhum.2011.207.00593

Danielsson, H., Henry, L., Rönnberg, J., & Nilsson, L.-G. (2010). Executive functions in individuals with intellectual disability. Research in Developmental Disabilities, 31, 1299-1304.

Schmidt, R., Launer, L. J., Nilsson, L.-G, Pajak, A., Sans, S., Berger, K., Breteler, M. M., de Ridder, M., Dufoil, C., Giampaoli, S., & Hofman, A. (2004). MRI of the brain in diabetes mellitus: the cardiovascular determinants of dementia (CASCADE) study. Diabetes, 53, 687-692.

Maitland, S.B., Nyberg, L., Bäckman, L., Nilsson, L.-G., & Adolfsson, R. (2009). The search for structure: The temperament character of the Temperament and Character Inventory. In C. Herzog (Ed.), Cognition and aging: Methodologies and applications. Washington, DC: American Psychological Association.

Sternäng, O., Jonsson, B., Wahlin, Å., Nyberg, L., & Nilsson, L.-G (2010). Examination of the common cause account in a population-based longitudinal study with narrow age cohort design. Gerontology, 56, 553-563.

Sundström, A, Marklund, P, Nilsson, L.-G., & Nyberg, L. (2004). ApoE influences on neuropsychological function after mild head injury: Within-person comparisons. Neurology, 62, 1963-1966.

Bäckman, L., & Nilsson, L.-G. (1996). Semantic memory functioning across the adult life span. European Psychologist, 1, 27-33.

Larsson, M., Nilsson, L.-G., Olofsson, J., & Nordin, S. (2004). Demographic and cognitive predictors of cued odor identification - Evidence from a population-based study. Chemical Senses, 29, 547-554.

Rademakers, R., Sleegers, K., Theuns, J., Van der Broeck, M., Kacem, S.B., Nilsson, L.-G., Adolfsson, R., van Duin, C.M., Van Broeckhoven, C., & Cruts, M. (2005). Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease. Nerobiology of Aging, 26, 1145-1151.

Lind, J., Larsson, A., Persson, J., Ingvar, M., Nilsson, L.-G., Bäckman, L., Adolfsson, R., Cruts, M., Sleegers, K., Van Broeckhoven, C., & Nyberg, L. (2006). Reduced hippocampal volume in non-demented carriers of the Apolipoprotein E ?4: Relation to chronological age and recognition memory. NeuroscienceLetters, 396, 23-27.

Nilsson, L.-G., Söderlund, H., Berger, K., Breteler, M., de Ridder, M., Dufoil, C., Fuhrer, R., Giampoli, S., Hofman, A., Pajak, A., Sans, S., Schmidt, R., & Launer, L. J. (2005). Cognitive test battery of CASCADE: Tasks and data. Aging, Neuropsychology and Cognition, 12, 32-56.

Rönnlund, M., Lövdén, M., & Nilsson, L.-G. (2008). Cross-Sectional versus Longitudinal Age Gradients of Tower of Hanoi Performance: The Role of Practice Effects and Cohort Differences in Education. Aging, Neuropsychology and Cognition, 15, 40-67

Söderfjell, S., Molander, B., Johansson, H., Barnekow-Bergkvist, M., & Nilsson, L.-G. (2006). Muscoskeletal pain and performance on cognitive tasks over the adult life span. Scandinavian Journal of Psychology, 47, 349-359.

Karlsson, T., Börjesson, A., Adolfsson, R., & Nilsson, L.-G. (2002). Successive memory test performance and priming in Alzheimer's disease. Evidence from the word-fragment completion task. Cortex, 38, 341-355.

Berger, K., Launer, L., Hofman, A., Breteler, M., Nilsson, L.-G., Söderlund, H., Schmidt, R., Giampoli, S., Sans, S., Fuhrer, R., Dufoil, C., & Pajak, A. (2002). The association between white matter lesions and cognitive function in a pooled analysis of European, population studies in the Cascade project. Neurobiology of Aging, 23, 443-443.

Brändström, S., Schlette, P., Przybeck, T.R., Sigvardsson, S., Nilsson, L.-G., Cloninger, C.R., Nylander, P.-O., & Adolfsson, R. (1998). Swedish normative data on personality using the Temperament and Character Inventory (TCI). Comprehensive Psychiatry, 39, 122-128.

Nyberg, L., Maitland, S.B., Rönnlund, M., Bäckman, L., Dixon, R., Wahlin, Å., & Nilsson, L.-G. (2003). Selective adult age differences in an age-invariant multi-factor model of declarative memory. Psychology & Aging, 18, 149-160.

Lind, J., Persson, J., Ingvar, M., Larsson, A., Cruts, M., Van Broeckhoven, C., Adolfsson, R., Bäckman, L., Nilsson, L.-G., Petersson, K.M., & Nyberg, L. (2006). Reduced functional brain activity response in cognitively intact Apolipoprotein e4 carriers. Brain, 129, 1240-1248.

Vestergren, P., & Nilsson, L.-G. (2011). Perceived causes of everyday memory problems in a population-based sample aged 39-99. Applied Cognitive Psychology, 25, 641-646. Doi: 10.1002/acp.1734.

Sundström, A., Bergdahl, J., Nyberg, L., Bergdahl, M., & Nilsson, L.-G. (2011). Stressful negative life events and amalgam-related complaints. Community Dentistry and Oral Epidemiology, 39, 12-18. Doi: 10.1111/j.1600-0528.2010.00571.x

Dixon, R.A., & Nilsson, L.-G. (2004). Don't fence us in: Probing the frontiers of cognitive aging. In R. A. Dixon, L. Bäckman, & L.-G. Nilsson (Eds.), New frontiers in cognitive aging, pp. 3-14. New York: Oxford University Press.

Zhang, Y.M., Han, B., & Nilsson, L.-G. (2008). Executive functioning in older adults with mild cognitive impairment: MCI has effects on planning, but not on inhibition: Erratum. Aging, Neuropsychology and Cognition, 15(2), 256-256.

Nilsson, L.-G. (2006). Memory, aging, and dementia: The Betula Study. In S. Ballesteros (Ed.), Aging, cognition and neuroscience, pp. 51-52. Madrid: UNED Ediciones.

Yonker, J., Eriksson, E., Nilsson, L.-G. & Herlitz, A. (2003). Sex differences in episodic memory: Minimal influence of estradiol. Brain and Cognition, 52, 231-238.

Salami, A., Eriksson, J., Nyberg, L., & Nilsson, L.-G. (2012). Age-related white matter microsctructural differences are not major mediators of cognitive decline in aging. Biochemica et Biophysica Acta-Molecular Basis of Disease, 1822, 408-415. Doi: 10.1016/jbbadis.2011.09.001.

Rönnlund, M., & Nilsson, L.-G. (2008). The magnitude, generality, and determinants of Flynn effects on forms of declarative memory and visuospatial ability: Time-sequential analyses of data from a Swedish cohort study. Intelligence, 36, 192-209.

Larsson, M., Nyberg, L., Bäckman, L., Nilsson, L.-G. (2003). Effects on episodic memory of stimulus richness, intention to learn, and extra-study repetition: Similar profiles across the adult life span. Journal of Adult Development, 10, 67-73.

Rönnlund, M., Lövdén, M., & Nilsson, L.-G. (2001). Adult Age Differences in Tower of Hanoi Performance: Influence from Demographic and Cognitive Variables. Aging, Neuropsychology, and Cognition, 8, 269-283.

Bergdahl, M., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2008). Difference I apolipoprotein E type 4 allele (APOE-?4) among dentate and edentulous subjects. Gerodontology, 25(3), 179-186

Nixon Andreasson, A., Szulkin, R., Undén, A.-L., von Essen, J., Nilsson, L.-G., & Lekander, M. (in press). Inflammation and positive affect related to subjective health: Women from the general population. Health Psychology.

Launer, L.J., Berger, K., Breteler, M.M.B., Dufoil, C., Fuhrer, R., Giampoli, S., Nilsson, L.-G., Pajak, A., de Ridder, M., van Dijk, E.J., Sans, S., Schmidt, R., & Hofman, A. (2006). Regional variability in the prevalence of cerebral white matter lesions: An MRI study in 9 European countries (CASCADE). Neuroepidemiology. 26, 23-29.

Olofsson, J.K., Nordin, S., Wiens, S., Hedner, M., Nilsson, L.-G., & Larssson, M. (2010). Odor identification impairment in carriers of ApoE-?4 is independent of dementia. Neurobiology of Aging, 31, 567-577.

Holmgren, S., Molander, B., & Nilsson, L.-G. (2008). Episodic memory in adult age and effects of sibship size and birth order: Longitudinal data. Journal of Adult Development, 14, 37-46.

Lövdén, M., Rönnlund, M., Wahlin, Å., Bäckman, L., Nyberg, L., & Nilsson, L.-G. (2004). The Extent of Stability and Change in Episodic and Semantic Memory in Old Age: Demographic Predictor of level and Change. Journal of Gerontology: Psychological Sciences, 59, P130-P134.

Persson, J., Bringlöv, E., Nilsson L.-G., & Nyberg, L. (2005). Herbal extracts and memory enhancement: Response to Scholey et al. Psychopharmacology, 179, 708-709.

Nilsson, L.-G. (2004). Våra långtidsminnen. [Our long-term memories]. Tvärsnitt, 3, 22-26.

Wahlin, Å., MacDonald, S.W.S., de Frias, C.M., Nilsson, L.-G., & Dixon, R.A. (2006). How health an biological age influences chronological age and sex differences in cognitive aging: Moderating, mediating, or both? Psychology and Aging, 21, 318-332.

Söderfjell, S., Molander, B., Barnekow-Bergkvist, M., Lyskov, E., Johansson, H., & Nilsson, L.-G. (2000). Aging, stress, and musculosceletal problems. International Journal of Psychology, 35, 367.

Persson, J., Kalpouzos, G., Nilsson, L.-G., Ryberg, M., & Nyberg, L. (2011). Preserved hippocampus activation in normal aging as revealed by fMRI. Hippocampus, 21, 753-766. Doi: 10.1002/hipo.20794.

Nilsson, L.-G. (2003). Memory function in normal aging. Acta Neurologica Scandinavica, 107, 7-13.

Rönnlund, M., Nyberg, L., Bäckman, L., & Nilsson, L.-G. (2005). Stability, growth, and decline in adult life-span development of declarative memory: Cross-sectional and longitudinal data from a population-based sample. Psychology and Aging, 20, 3-18.

Hansson, P., Rönnlund, M., Juslin, P., & Nilsson, L.-G. (2008). Adult age diffeerences in the realism of confidence judgments: Overconfidence, formal dependence, and cognitive predictors. Psychology and Aging, 23(3), 531-544.

Rönnlund, M., Lövdén, M., Ljungberg, J., Nordin, M., & Nilsson, L.-G. (2000). Adult age differences in Tower of Hanoi performance: Evidence from the Betula prospective cohort study. International Journal of Psychology, 35, 366.

Nyberg, L., Persson, J., & Nilsson, L.-G. (2002). Individual differences in memory enhancement by encoding enactment: Relationships to adult age and biological factors. Neuroscience and Biobehavioral Review, 26, 835-839.

Öhman, L., Bergdahl, J., Nyberg, L., & Nilsson, L.-G. (2007). Longitudinal analysis of the relation between moderate long-term stress and health. Stress and Health, 23, 131-138.

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Dataset 1
Betula - aging, memory and dementia: 1988-1990

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 1988–1990
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1988–1990
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1988–1990
  • Source of the data: Population group, Biological samples
Dataset 2
Betula - aging, memory and dementia: 1993-1995

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 1993–1995
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1993–1995
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1993–1995
  • Source of the data: Population group, Biological samples
Dataset 3
Betula - aging, memory and dementia: 1998-2000

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1998–2000
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1998–2000
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 1998–2000
  • Source of the data: Population group, Biological samples
Dataset 4
Betula - aging, memory and dementia: 2003-2005

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2003–2005
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 2003–2005
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2003–2005
  • Source of the data: Population group, Biological samples
Dataset 5
Betula - aging, memory and dementia: 2008-2010

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2008–2010
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2008–2010
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 2008–2010
  • Source of the data: Population group, Biological samples
Dataset 6
Betula - aging, memory and dementia: 2013-2014

Data format / data structure

Numeric

Creator/Principal investigator(s)

Lars Nyberg - Umeå University, Integrative Medical Biology

Lars-Göran Nilsson - Stockholm University, Department of Psychology

Rolf Adolfsson - Umeå university, Psyciatry

Lars Bäckman - Karolinska Institutet, Institutionen för Neurobiologi, Vårdvetenskap och Samhälle

Data collection 1

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2013–2014
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2013–2014
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Psychological measurements and tests
  • Time period(s) for data collection: 2013–2014
  • Source of the data: Population group, Biological samples
Published: 2012-01-01
Last updated: 2017-04-12