OPRA: Population based prospective study of bone metabolism, bone mineral, tendency to fall and fracture incidence in 75-year-old women

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s):

Kristina Åkesson - Lund university, Department of Clinical Sciences orcid

Description:

In the study a group of women in which age-related bone loss is already clear and common fractures at baseline are investigated. The expected increase in fracture incidence, especially of the hip, takes place within the time frame of the study. The cohort is of sufficient size to allow the sub-grouping, e.g. for fracture type. Furthermore, the study allows detailed evaluation of genes associated with bone loss, such as the elderly.

Research subjects were randomly selected from the population register. During the years 1995-1999 were treated in 1604 75-year-old women in (33% of all 75-year-old women in Malmö during the period). Of these women, participated in 1044 at the first visit. All of the study participants was 75 years at the first visit, of northern European descent, and residents in the city of Malmö. Follow-up visits occurred at 76, 78, 80 and 85 years of age.

Data have been collected​​ during the visits, by measuring height, weight, bone density, body fat percentage, muscle mass, by physiotherapist tests (muscle strength, walking speed, balance), as well as through an exten

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Responsible department/unit:

Creator/Principal investigator(s):

Kristina Åkesson - Lund university, Department of Clinical Sciences orcid

Identifiers:

SND-ID: EXT 0077

Purpose:

To study the factors that influence bone density, bone loss and fracture risk in older women - the group with highest risk of developing osteoporosis

Description:

In the study a group of women in which age-related bone loss is already clear and common fractures at baseline are investigated. The expected increase in fracture incidence, especially of the hip, takes place within the time frame of the study. The cohort is of sufficient size to allow the sub-grouping, e.g. for fracture type. Furthermore, the study allows detailed evaluation of genes associated with bone loss, such as the elderly.

Research subjects were randomly selected from the population register. During the years 1995-1999 were treated in 1604 75-year-old women in (33% of all 75-year-old women in Malmö during the period). Of these women, participated in 1044 at the first visit. All of the study participants was 75 years at the first visit, of northern European descent, and residents in the city of Malmö. Follow-up visits occurred at 76, 78, 80 and 85 years of age.

Data have been collected​​ during the visits, by measuring height, weight, bone density, body fat percentage, muscle mass, by physiotherapist tests (muscle strength, walking speed, balance), as well as through an exten

... Show more..

Time period(s) investigated:

1995 — 1999

Geographic spread:

Geographic description: city of Malmö

Unit of analysis:

Contact person for questions about the data:

Kristina Åkesson

Is part of collection at SND:

Scania Metadatabase for Epidemiology (SME)

OPRA: Population based prospective study of bone metabolism, bone mineral, tendency to fall and fracture incidence in 75-year-old women

Data format / data structure:

Numeric

Data collection:

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 1995 — 1999

Source of the data: Population group, Biological samples

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 1995 — 1999

Source of the data: Population group, Biological samples

Time period(s) investigated:

1995 — 1999

Number of individuals/objects:

1044

Response rate/participation rate:

65%