Wife and husband DNA cohort

SND-ID: EXT 0101

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Description

The cohort was recruited among accompanying spouses of cancer patients at the Oncology Clinic at Lund University Hospital. The study will be used as a reference population in genetic studies and in studies on biomarkers. The individuals filled in a questionnaire about their health status and donated a blood sample.

Purpose:

The study will be used as a reference population in genetic studies and in studies on biomarkers.
Research principal, contributors, and funding

Research principal

Lund University

Responsible department/unit

Faculty of Medicine

Protection and ethical review

Ethics Review

Lund

Method and time period

Unit of analysis

Population

The population is based on spouses of cancer patients at the Oncology Clinic at Lund University Hospital.

Sampling procedure

Non-probability: Purposive

Time period(s) investigated

2007-01-01 – ongoing

Biobank is connected to the study

Yes

Geographic coverage
Publications

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Broberg K, Höglund M, Gustafsson C, Björk J, Ingvar C, Albin M, Olsson H. Genetic variant of the human homologous recombination-associated gene RMI1 (S455N) impacts the risk of AML/MDS and malignant melanoma. Cancer Lett. 2007 Dec 8;258(1):38-44.

Broberg K, Huynh E, Schläwicke Engström K, Björk J, Albin M, Ingvar C, Olsson H, Höglund M. Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study. BMC Cancer. 2009 May 11;9:140.
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Dataset
Wife and husband DNA cohort

Description

Data collection is ongoing. The study is planned to include 5,000 individuals.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Time period(s) investigated

2007-01-01 – ongoing

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2007–ongoing
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2007–ongoing
  • Source of the data: Population group, Biological samples

Number of individuals/objects

1500

Response rate/participation rate

>99 %

Contact for questions about the data

Is part of collection at SND

Scania Metadatabase for Epidemiology (SME)

Published: 2014-05-05
Last updated: 2017-01-03