MISS-cohort, Melanoma in Southern Sweden

This study is part of the collection Swedish Cohort Consortium (Cohorts.se) , Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s):

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Christian Ingvar - Lund University, Faculty of Medicine, Surgery

Description:

The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. The interviews were conducted between 1990 and 1992 and the questions concerned, among other things, the time for the woman's first menstruation, number of pregnancies, age at entry into menopause, contraception, alcohol, smoking, sun exposure and constitutional factors. The cohort was interviewed one more time in year 2000 and again 2011. Re-interviews are scheduled for every ten years. During 2011 to 2013 DNA was collected from the cohort through saliva. Follow-up of morbidity and mortality are made annually through the national registry.

Responsible department/unit:

Creator/Principal investigator(s):

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Christian Ingvar - Lund University, Faculty of Medicine, Surgery

Identifiers:

SND-ID: EXT 0102

Purpose:

The aim of this study was to create a prospective population-based cohort of women from Southern Sweden with information regarding environmental and genetic factors.

Description:

The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. The interviews were conducted between 1990 and 1992 and the questions concerned, among other things, the time for the woman's first menstruation, number of pregnancies, age at entry into menopause, contraception, alcohol, smoking, sun exposure and constitutional factors. The cohort was interviewed one more time in year 2000 and again 2011. Re-interviews are scheduled for every ten years. During 2011 to 2013 DNA was collected from the cohort through saliva. Follow-up of morbidity and mortality are made annually through the national registry.

Time period(s) investigated:

1990 — ongoing

Geographic spread:

Geographic description: Southern Sweden

Unit of analysis:

Population:

Women between 25 and 65 years, living in Southern Sweden.

Sampling procedure:

Probability: Simple random

Contact persons for questions about the data:

Håkan Olsson

Christian Ingvar

Is part of collection at SND:

Swedish Cohort Consortium (Cohorts.se)

Scania Metadatabase for Epidemiology (SME)

Publications

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Olsson H, Bladström A. A cohort study of reproductive factors and family history of breast cancer in southern Sweden. Breast Cancer Res Treat. 2002 Dec;76(3):203-9.

Epstein E, Lindqvist PG, Geppert B, Olsson H. A population-based cohort study on sun habits and endometrial cancer. Br J Cancer. 2009 Aug 4;101(3):537-40.
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Dataset EXT 0102-001

MISS-cohort, Melanoma in Southern Sweden

Data format / data structure:

Numeric

Data collection:

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 1990 — 1992

Source of the data: Population group, Biological samples

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2000 — 2000

Source of the data: Population group, Biological samples

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2011 — 2011

Source of the data: Population group, Biological samples

Number of individuals/objects:

29508

Response rate/participation rate:

74 %

Dataset EXT 0102-002

MISS-cohort, Melanoma in Southern Sweden

Data format / data structure:

Numeric

Data collection:

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2011 — 2013

Source of the data: Population group, Biological samples

Number of individuals/objects:

15000

Response rate/participation rate:

ca 50 %