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MISS-cohort, Melanoma in Southern Sweden

SND-ID: EXT 0102

This study is part of the collection Swedish Cohort Consortium (Cohorts.se) , Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Christian Ingvar - Lund University, Faculty of Medicine, Surgery

Description

The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. The interviews were conducted between 1990 and 1992 and the questions concerned, among other things, the time for the woman's first menstruation, number of pregnancies, age at entry into menopause, contraception, alcohol, smoking, sun exposure and constitutional factors. The cohort was interviewed one more time in year 2000 and again 2011. Re-interviews are scheduled for every ten years. During 2011 to 2013 DNA was collected from the cohort through saliva. Follow-up of morbidity and mortality are made annually through the national registry.

Purpose:

The aim of this study was to create a prospective population-based cohort of women from Southern Sweden with information regarding environmental and genetic factors.
Research principal, contributors, and funding

Research principal

Lund University

Responsible department/unit

Lund University, Faculty of Medicine
Protection and ethical review
Method and time period

Unit of analysis

Population

Women between 25 and 65 years, living in Southern Sweden.

Time Method

Sampling procedure

Probability: Simple random

Time period(s) investigated

1990 – ongoing

Geographic coverage

Geographic spread

Geographic description: Southern Sweden

Topic and keywords

Research area

HEALTH (CESSDA Topic Classification)
Medical Genetics, Clinical Medicine, Cancer and Oncology (The Swedish standard of fields of research 2011)

Keywords

contraceptive devices, epidemiologic methods, cohort studies, body weights and measures, menopause, women's health, neoplasms, biomarkers, reproduction, smoking, saliva, sun exposure, cohorts.se, scania, epihealth_skåne, epihealth, swedish cohort consortium (scc), genetic studies

Publications

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Olsson H, Bladström A. A cohort study of reproductive factors and family history of breast cancer in southern Sweden. Breast Cancer Res Treat. 2002 Dec;76(3):203-9.

Epstein E, Lindqvist PG, Geppert B, Olsson H. A population-based cohort study on sun habits and endometrial cancer. Br J Cancer. 2009 Aug 4;101(3):537-40.
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Access to data via

Dataset 1
MISS-cohort, Melanoma in Southern Sweden

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Christian Ingvar - Lund University, Faculty of Medicine, Surgery

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1990–1992
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2000–2000
  • Source of the data: Population group, Biological samples

Data collection 3

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2011–2011
  • Source of the data: Population group, Biological samples

Number of individuals/objects

29508

Response rate/participation rate

74%

Dataset 2
MISS-cohort, Melanoma in Southern Sweden

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Christian Ingvar - Lund University, Faculty of Medicine, Surgery

Data collection

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2011–2013
  • Source of the data: Population group, Biological samples

Number of individuals/objects

15000

Response rate/participation rate

ca 50 %

Contacts for questions about the data

Is part of collection at SND

Swedish Cohort Consortium (Cohorts.se)

Scania Metadatabase for Epidemiology (SME)

Published: 2014-05-15
Last updated: 2017-02-09