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Case control study of risk factors of melanoma

SND-ID: EXT 0103

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Description

Since 1988, individuals affected by melanoma in Southern Sweden has been interviewed and the cohort now consists of 3000 cases. For each case, two controls are randomly selected from the Skåne population registry and matched for sex, age and place of residence. The same questions have been sent also to the controls. These questions concern, among others, past illnesses, medication, exposure to UV light, alcohol, smoking, use of oral contraceptivesion and education. All patients with familial melanoma have been analyzed for a CDKN2A mutation. During 1995-96 blood was collected from all patients, but beyond that they have only blood collected from cases with familiar melanoma, cases aged under 40 and cases with multiple melanoma. The study is still ongoing.

Purpose:

The aim of the study is to create a cohort of patients with melanoma and controls to study risk factors for the disease.
Research principal, contributors, and funding

Research principal

Lund University

Responsible department/unit

Faculty of Medicine

Protection and ethical review
Method and time period

Unit of analysis

Population

Individuals affected by melanoma in Southern Sweden and controls matched for sex, age and place of residence.

Study design

Case-control study

Sampling procedure

Probability: Systematic random

Time period(s) investigated

1988 – ongoing

1995 – 1996

Biobank is connected to the study

Yes

Geographic coverage

Geographic spread

Geographic description: Southern Sweden

Topic and keywords

Research area

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Medical Genetics, Clinical Medicine, Cancer and Oncology (The Swedish standard of fields of research 2011)

Keywords

contraceptive devices, blood specimen collection, body weights and measures, neoplasms, alcohol drinking, medical history taking, case-control studies, reproduction, smoking, education, melanoma, epihealth, sun exposure, blood sample, epihealth_skåne, genetic studies, alcohol, scania

Publications

Westerdahl J, Olsson H, Måsbäck A, Ingvar C, Jonsson N, Brandt L, Jönsson PE, Möller T. Use of sunbeds or sunlamps and malignant melanoma in southern Sweden. Am J Epidemiol. 1994 Oct 15;140(8):691-9.
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Dataset 1
Study of risk factors for melanoma - cases

Associated documentation

Description

Dataset includes the cases in the study.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1988–ongoing
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1995–1996
  • Source of the data: Population group, Biological samples

Number of individuals/objects

3000

Dataset 2
Study of risk factors for melanoma - controls

Associated documentation

Description

Dataset includes the control group in the study.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1988–ongoing
  • Source of the data: Population group, Biological samples

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1995–1996
  • Source of the data: Population group, Biological samples

Number of individuals/objects

6000

Contact for questions about the data

Is part of collection at SND

Scania Metadatabase for Epidemiology (SME)

Published: 2014-05-16
Last updated: 2019-11-15