Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Description
Purpose:
To study risk factors studies in hereditary breast cancer
Research principal
Responsible department/unit
Faculty of Medicine
Unit of analysis
Population
The population includes all men and women, tested for mutation BRCA1 or 2 in the southern health region since 1993.
Time Method
Sampling procedure
Time period(s) investigated
1993 – ongoing
Research area
HEALTH
(CESSDA Topic Classification)
Medical Genetics, Cancer and Oncology
(The Swedish standard of fields of research 2011)
Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, et al. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet. 2008 Apr;82(4):937-48. doi: 10.1016/j.ajhg.2008.02.008.
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Osorio A, Milne RL, Pita G, Peterlongo P, Heikkinen T, Simard J, et al. Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA). Br J Cancer. 2009 Dec 15;101(12):2048-54. doi: 10.1038/sj.bjc.6605416.
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Description
The dataset includes all men and women, tested for mutations in BRCA1 or BRCA2, in the southern health region since 1993.Data format / data structure
Numeric
Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Number of individuals/objects
1200