Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Description
Purpose:
To find tumor markers or tumor cells in the blood from patients with metastatic breast cancer.
Research principal
Responsible department/unit
Faculty of Medicine, The Division of Oncology and Pathology
Unit of analysis
Population
Individuals with metastatic breast cancer, treated at the oncologist in Lund.
Time Method
Sampling procedure
Time period(s) investigated
2003 – ongoing
Research area
HEALTH
(CESSDA Topic Classification)
Clinical Medicine, Cancer and Oncology
(The Swedish standard of fields of research 2011)
Carlsson MC, Cederfur C, Schaar V, Balog CI, Lepur A, Touret F, Salomonsson E, Deelder AM, Fernö M, Olsson H, Wuhrer M, Leffler H. Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients. PLoS One. 2011;6(10):e26560. doi: 10.1371/journal.pone.0026560. Epub 2011 Oct 18.
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Carlsson A, Wingren C, Kristensson M, Rose C, Fernö M, Olsson H, Jernström H, Ek S, Gustavsson E, Ingvar C, Ohlsson M, Peterson C, Borrebaecka C A.K. Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases. Proc Natl Acad Sci U S A. Aug 23, 2011; 108(34): 14252-14257. doi: 10.1073/pnas.1103125108. Published online Aug 15, 2011.
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Carlsson A, Wingren C, Ingvarsson J, Ellmark P, Baldertorp B, Fernö M, Olsson H, Borrebaeck CA. Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays. Eur J Cancer. 2008 Feb;44(3):472-80. doi: 10.1016/j.ejca.2007.11.025. Epub 2008 Jan 2.
Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H. Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease. Biochim Biophys Acta. 2012 Sep;1820(9):1366-72. doi: 10.1016/j.bbagen.2012.01.007. Epub 2012 Jan 17.
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Access to data via
Contact
Håkan Olsson
Description
Data collection was started in 2003 and is ongoing (in 2010 there were over 300 individuals included in the study).Data format / data structure
Numeric
Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Number of individuals/objects
310