Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Description
In this unique Swedish study, which started in September 2008, all new and prevalent cancer cases in southern Sweden are included to create a family history data bank. All children ≤18 years of age with a malignant disease in the Southern Swedish Health Care Region (approximately 1.8 million inhabitants) are referred for care to the Department of Pediatrics at the Skåne University Hospital in Lund. Patients with a newly diagnosed malignancy and patients visiting the clinics for follow-up after completed treatment were invited to participate in the study. The eligibility criteria include (a) a diagnosis before 19 years of age with a malignancy following codes ICD 140 to 209 and (b) a diagnosis after 1970. Blood samples are collected and the patients and their parents are requested to complete a self-reported questionnaire, assessing name, date of birth, date of death, and history of cancer among first-, second- and third degree relatives. In addition a question about cancer in more distant relatives is included. Information regarding specific type of cancer and date of, or age at, diagnosis for
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Responsible department/unit
Region Skåne, Faculty of Medicine, The Division of Oncology and PathologyUnit of analysis
Population
All new and prevalent cases of cancer among children in the Southern Swedish Health Care Region.
Time Method
Sampling procedure
Time period(s) investigated
2008-09 – ongoing
Research area
HEALTH
(CESSDA Topic Classification)
Medical Genetics, Cancer and Oncology, Pediatrics, Other Clinical Medicine
(The Swedish standard of fields of research 2011)
Magnusson S, Wiebe T, Kristoffersson U, Jernström H, Olsson H. Increased incidence of childhood, prostate and breast cancers in relatives of childhood cancer patients. Fam Cancer. 2012 Mar;11(1):145-55. doi: 10.1007/s10689-011-9493-3.
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Description
Family history data bank, based on all new and prevalent cancer cases in the Southern Swedish Health Care Region. Until 2014 there were 650 children included in the study, and blood from 125 parents. The response rate is between 30-40%.Data format / data structure
Numeric
Creator/Principal investigator(s)
Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology
Response rate/participation rate
ca 30- 40 %