BIG3

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Ulf Malmqvist - Region Skåne

Description

BIG3 is a Scanian research project in which the name BIG3 is aiming at three major diseases: chronic obstructive pulmonary disease (COPD), cardiovascular diseases and lung cancer. The overall goal of BIG3 is to understand the mechanisms underlying these diseases in order to develop new treatments that can lead to earlier, better and more accurate diagnosis for better and more individualized treatment. BIG3 is an open prospective longitudinal cohort study in Sweden.
As a first step, around 100 000 people in Scania between 45 and 75 years have the opportunity to answer a questionnaire about lifestyle, living environment and tobacco habits. Then about 10 000 individuals from the respondents will be summoned to undergo examinations. These include ECG, CT scan of the heart and lungs, pulmonary function tests and blood tests. The blood samples will be analyzed both directly for a number of markers and also stored in a biobank for later analysis. The goal is to try to get about 50% of smokers in the cohort.

Ultimately, the study aims to find out which individuals that are at greater risk of develo

... Show more..

Responsible department/unit

Region Skåne

Creator/Principal investigator(s)

Ulf Malmqvist - Region Skåne

Identifiers

SND-ID: EXT 0129

Description

BIG3 is a Scanian research project in which the name BIG3 is aiming at three major diseases: chronic obstructive pulmonary disease (COPD), cardiovascular diseases and lung cancer. The overall goal of BIG3 is to understand the mechanisms underlying these diseases in order to develop new treatments that can lead to earlier, better and more accurate diagnosis for better and more individualized treatment. BIG3 is an open prospective longitudinal cohort study in Sweden.
As a first step, around 100 000 people in Scania between 45 and 75 years have the opportunity to answer a questionnaire about lifestyle, living environment and tobacco habits. Then about 10 000 individuals from the respondents will be summoned to undergo examinations. These include ECG, CT scan of the heart and lungs, pulmonary function tests and blood tests. The blood samples will be analyzed both directly for a number of markers and also stored in a biobank for later analysis. The goal is to try to get about 50% of smokers in the cohort.

Ultimately, the study aims to find out which individuals that are at greater risk of develo

... Show more..

Time period(s) investigated

2013 — ongoing

Unit of analysis

Population

100 000 individuals between 45-77 years, residing in Scania.

Sampling procedure

Probability

Ethics Review

Lund — Ref. 2011/371, 2012474, 2013/350, 2013/856 samt 2014/535

Biobank is connected to the study

Yes

Contact for questions about the data

Ulf Malmqvist

Is part of collection at SND

Scania Metadatabase for Epidemiology (SME)

Download metadata

Dataset 1

Survey

Creator/Principal investigator(s)

Ulf Malmqvist - Region Skåne

Description

As a first step, around 100,000 individuals between 45 and 75 years and living in Scania have the opportunity to answer a questionnaire about lifestyle and health. Until September 2014, the number of respondents to the questionnaire was about 3000.

Data format / data structure

Numeric

Data collection

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2013

Source of the data: Population group, Biological samples

Time period(s) investigated

2013 — ongoing

Dataset 2

Examination

Creator/Principal investigator(s)

Ulf Malmqvist - Region Skåne

Description

In the second stage, approximately 10 000 individuals of those submitted the questionnaire, are randomly invited to an examination at Skåne University Hospital. Until September 2014, approximately 1000 individuals completed an examination.

Data format / data structure

Numeric

Data collection

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2013

Source of the data: Population group, Biological samples

Time period(s) investigated

2013 — ongoing

Published: 2014-10-27
Last updated: 2019-11-15