Case control study for soft tissue sarcoma

SND-ID: EXT 0137

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Description

The etiology of soft tissue sarcomas is largely unknown. For this study, which started in 1988 and still is in progress, information has been collected from individuals with soft tissue sarcomas and also from healthy controls. All patients, 15 years of age and older, diagnosed with soft tissue sarcoma (excluding those with tumors of the uterus) in southern Sweden have been identified from Southern Swedish regional tumor registry. Until 2009 there were 1261 individuals who were contacted and asked if they could answer a questionnaire. The questionnaire contained questions relating to past illnesses and medication, previous radiation therapy, occupation, height, weight, reproduction, use of oral contraceptives and other exposure to hormonal substances. Two controls per case were randomly selected from the population registry with matching criterias gender, age and place of residence. Of the 1261 identified cases, 967 (77%) responded to the questionnaire. After exclusion of some individuals due to misclassification 855 cases and 2021 controls remained. Due to the lack of available controls for 22

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Research principal, contributors, and funding

Research principal

Lund University

Responsible department/unit

Faculty of Medicine, The Division of Oncology and Pathology

Protection and ethical review
Method and time period

Unit of analysis

Population

All patients, 15 years of age and older, diagnosed with soft tissue sarcoma (excluding those with tumors of the uterus) in southern Sweden, identified from the Southern Swedish regional tumor registry.

Study design

Case-control study

Sampling procedure

Non-probability

Time period(s) investigated

1988 – ongoing

Geographic coverage
Publications

Wagner P, Alvegård T, Ranstam J, Rydholm A, Vult von Steyern F, Olsson H. Oral contraceptive use, parity, and constitutional characteristics. Cancer Causes Control. 2014 Sep;25(9):1167-77. doi: 10.1007/s10552-014-0420-4.

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Dataset 1
Study of risk factors for soft tissue sarcoma-cases

Description

Data collection is ongoing. In 2009, the study consisted of 634 cases.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Data collection

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1988–ongoing
  • Source of the data: Population group

Number of individuals/objects

634

Dataset 2
Study of risk factors for soft tissue sarcoma-controls

Description

Data collection is ongoing. In 2009, the study consisted of 1251 cases.

Data format / data structure

Numeric

Creator/Principal investigator(s)

Håkan Olsson - Lund University, Faculty of Medicine, The Division of Oncology and Pathology

Data collection

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1988–ongoing
  • Source of the data: Population group

Number of individuals/objects

1251

Contact for questions about the data

Is part of collection at SND

Scania Metadatabase for Epidemiology (SME)

Published: 2014-12-11
Last updated: 2019-12-17