DIWA - Diabetes and Impaired glucose tolerance in Women and Atherosclerosis development study

Overview Description Data

Creator/Principal investigator(s):

Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine

Description:

All 64-year old women in the county of Gothenburg were invited to a screening examination including an OGTT. Glucose tolerance was defined for each participant according to the World Health Organization (WHO) criteria. Patients were divided in three sub-groups according to metabolic status and a randomized sample of patients were recruited from each group for a longitudinal follow-up study: diabetes mellitus (n = 220), impaired glucose tolerance (IGT, n = 204) or normal glucose tolerance (NGT, n = 188). Baseline examination was performed between 2002-2004 and follow-up examination in 2007-2009 (mean follow-up 5.5 years).
Datasets from papers published in open access is made available on request.

Purpose:

The aim of the DIWA-study is to investigate the development of atherosclerosis in women with different degrees of glucose control.

Subject area:

HEALTH (CESSDA Topic Classification)
Endocrinology and Diabetes (The Swedish standard of fields of research 2011)

Keywords:

Longitudinal Studies, Glucose Tolerance Test, Women, Atherosclerosis, Glucose, Mass Screening, Diabetes Mellitus, Type 2, metabolic status

Principal organisation:

University of Gothenburg

Accessibility status:

Access to data through an external actor
Access to data is restricted

Homepage:

The study homepage

Responsible department/unit:

University of Gothenburg, Institute of Medicine

Creator/Principal investigator(s):

Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine

Identifiers:

SND-ID: EXT 0140

Description:

Time period(s) investigated:

2002 — ongoing

Geographic spread:

Geographic description: Gothenburg

Unit of analysis:

Individual

Population:

64-year old women in Gothenburg (2002)

Time Method:

Longitudinal: Cohort: Prospective

Sampling procedure:

Probability: Stratified

Biobank is connected to the study:

Yes

Subject area:

HEALTH (CESSDA Topic Classification)
Endocrinology and Diabetes (The Swedish standard of fields of research 2011)

Keywords:

Longitudinal Studies, Glucose Tolerance Test, Women, Atherosclerosis, Glucose, Mass Screening, Diabetes Mellitus, Type 2, metabolic status

Contact for questions about the data:

Rufus Latham

Download metadata:

Publications

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Fagerberg B, Prahl Gullberg U, Alm R, Nilsson J, Nordin Fredrikson G. Circulating autoantibodies against the apolipoprotein B-100 peptides p45 and p210 in relation to the occurrence of carotid plaques in 64-year-old women. PLoS ONE 2015;10(3): e0120744. doi:10.1371/journal.pone.0120744
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Bergström G, Fagerberg B, Sallsten G, Lundh T, Barregard L. Is cadmium exposure associated with the burden, vulnerability and rupture of human atherosclerotic plaques? PLOS ONE (in press).

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