Creator/Principal investigator(s)
Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine
Description
The study sample collected between 2003-2009 consist of symptomatic carotid atherosclerotic plaques obtained from carotid endarterectomies performed at the Sahlgrenska University Hospital (Göteborg, Sweden). Criteria qualifying for surgery were minor ischemic stroke, transient ischemic attack (TIA) or amaurosis fugax and a high-grade carotid stenosis (≧70% determined with the European Carotid Surgery Trial method).
In 2010 the Collection of data was restarted with emphasis on collecting complete time series of endareterctomies. A further expansion led to inclusion of serum and plasma samples taken from patients with newly diagnosed abdominal aortic aneurysms (AAA). The latter Collection is also reffered to as the G3A study (Gothenburg Abdominal Aortic Aneurysm study) and led by Dr Marcus Langensköld.
Datasets from papers published in open access is made available on request.
Purpose:
A biobank of human atherosclerotic tissue harvested at carotid endarerectomy.
Research principal
Responsible department/unit
Institute of Medicine
Unit of analysis
Population
Patients undergoing endareterctomies at Sahlgrenska University Hospital.
Time Method
Sampling procedure
Time period(s) investigated
2003 – ongoing
Biobank is connected to the study
Yes
Geographic spread
Geographic description: Region Västra Götaland
Research area
HEALTH
(CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine
(The Swedish standard of fields of research 2011)
Bergström G, Fagerberg B, Sallsten G, Lundh T, Barregard L. Is cadmium exposure associated with the burden, vulnerability and rupture of human atherosclerotic plaques? PLOS ONE (in press).
If you have published anything based on these data, please notify us with a reference to your publication(s). If you are responsible for the catalogue entry, you can update the metadata/data description in DORIS.
Data format / data structure
Numeric
Creator/Principal investigator(s)
Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine
Time period(s) investigated
2003 – ongoing