Gothenburg Atheroma Study Group (GASG)

Creator/Principal investigator(s):

Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine

Description:

Study population and examinations

The study sample collected between 2003-2009 consist of symptomatic carotid atherosclerotic plaques obtained from carotid endarterectomies performed at the Sahlgrenska University Hospital (Göteborg, Sweden). Criteria qualifying for surgery were minor ischemic stroke, transient ischemic attack (TIA) or amaurosis fugax and a high-grade carotid stenosis (≧70% determined with the European Carotid Surgery Trial method).

In 2010 the Collection of data was restarted with emphasis on collecting complete time series of endareterctomies. A further expansion led to inclusion of serum and plasma samples taken from patients with newly diagnosed abdominal aortic aneurysms (AAA). The latter Collection is also reffered to as the G3A study (Gothenburg Abdominal Aortic Aneurysm study) and led by Dr Marcus Langensköld.

Datasets from papers published in open access is made available on request.

Creator/Principal investigator(s):

Göran Bergström - University of Gothenburg, The Sahlgrenska Academy, Institute of Medicine

Identifiers:

SND-ID: EXT 0141

Purpose:

A biobank of human atherosclerotic tissue harvested at carotid endarerectomy.

Description:

Study population and examinations

The study sample collected between 2003-2009 consist of symptomatic carotid atherosclerotic plaques obtained from carotid endarterectomies performed at the Sahlgrenska University Hospital (Göteborg, Sweden). Criteria qualifying for surgery were minor ischemic stroke, transient ischemic attack (TIA) or amaurosis fugax and a high-grade carotid stenosis (≧70% determined with the European Carotid Surgery Trial method).

In 2010 the Collection of data was restarted with emphasis on collecting complete time series of endareterctomies. A further expansion led to inclusion of serum and plasma samples taken from patients with newly diagnosed abdominal aortic aneurysms (AAA). The latter Collection is also reffered to as the G3A study (Gothenburg Abdominal Aortic Aneurysm study) and led by Dr Marcus Langensköld.

Datasets from papers published in open access is made available on request.

Time period(s) investigated:

2003 — ongoing

Geographic spread:

Geographic description: Region Västra Götaland

Unit of analysis:

Population:

Patients undergoing endareterctomies at Sahlgrenska University Hospital.

Time Method:

Sampling procedure:

Total universe/Complete enumeration

Biobank is connected to the study:

Yes

Contact person for questions about the data:

Göran Bergström

Publications

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Bergström G, Fagerberg B, Sallsten G, Lundh T, Barregard L. Is cadmium exposure associated with the burden, vulnerability and rupture of human atherosclerotic plaques? PLOS ONE (in press).

If you have published anything based on these data, please notify us with a reference to your publication(s).

Data format / data structure:

Numeric

Data collection:

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2003 — 2009

Source of the data: Biological samples

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2010 — 2010

Source of the data: Biological samples

Time period(s) investigated:

2003 — ongoing