The European Dermato-Epidemiology Network (EDEN) Fragrance Study

This study is part of the collection Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s):

Åke Svensson - Region Skåne, Dermatology, Malmö

Ewa Wallin - Region Skåne, Dermatology, Malmö

Description:

Contact allergy to fragrances appears to be increasing and data on allergy in the general population are limited. The EDEN cohort is a multinational study that involves several areas in five European countries (Sweden, Italy, Germany, The Netherlands and Portugal). The study was conducted during August 2008 to October 2011.

In total 12 000 individuals from these five countries was interviewed and about 3000 of these also underwent a patch test for different fragrance allergens. From Sweden 2069 individuals participated. The questionnaire contained questions concerning occupation, smoking, anthropometric data, previous experience with skin rash, and any history of reactions to products that may contain the sensitizer and/or a history of avoidance of the same products (e.g. skin lotions, deodorants, make-up and laundry detergent).

Responsible department/unit:

Creator/Principal investigator(s):

Åke Svensson - Region Skåne, Dermatology, Malmö

Ewa Wallin - Region Skåne, Dermatology, Malmö

Identifiers:

SND-ID: EXT 0151

Purpose:

To determine the prevalence and severity of contact allergy to fragrances and other sensitizers in the general population in Europe

Description:

Contact allergy to fragrances appears to be increasing and data on allergy in the general population are limited. The EDEN cohort is a multinational study that involves several areas in five European countries (Sweden, Italy, Germany, The Netherlands and Portugal). The study was conducted during August 2008 to October 2011.

In total 12 000 individuals from these five countries was interviewed and about 3000 of these also underwent a patch test for different fragrance allergens. From Sweden 2069 individuals participated. The questionnaire contained questions concerning occupation, smoking, anthropometric data, previous experience with skin rash, and any history of reactions to products that may contain the sensitizer and/or a history of avoidance of the same products (e.g. skin lotions, deodorants, make-up and laundry detergent).

Time period(s) investigated:

2008-08 — 2011-10

Geographic spread:

Geographic description: Malmö

Unit of analysis:

Population:

More than 2,000 individuals living in Malmö.

Time Method:

Sampling procedure:

Probability

Ethics Review:

Lund —351/2006 komplettering 2008/96

Contact persons for questions about the data:

Åke Svensson

Ewa Wallin

Is part of collection at SND:

Scania Metadatabase for Epidemiology (SME)

Available documentation:

Publications

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Rossi M, Coenraads PJ, Diepgen T, Svensson Å, Elsner P, Gonçalo M, Bruze M, Naldi L. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: the European Dermato-Epidemiology Network Fragrance Study. Dermatology. 2010;221(3):267-75. doi: 10.1159/000319757.

Naldi L, Cazzaniga S, Goncalo M, Diepgen T, Bruze M, Elsner P, Coenraads PJ, Svensson A, Bertuccio P, Ofenloch R, EDEN Fragrance Study Group. Prevalence of self-reported skin complaints and avoidance of common daily life consumer products in selected European Regions. JAMA Dermatol 2014;150:154-63. oi: 10.1001/jamadermatol.2013.7932.
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EDEN-the Swedish part

Description:

Participants from Sweden were 2069 individuals.

Data format / data structure:

Numeric

Data collection:

Mode of collection: Face-to-face interview

Time period(s) for data collection: 2008-08 — 2011-10

Source of the data: Population group

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2008-08 — 2011-10

Source of the data: Population group

Number of individuals/objects:

2069