Creator/Principal investigator(s)
Margareta Kristenson - Linköping University, Department of Medical and Health Sciences
Description
Also the welfare state of Sweden has prominent socioeconomic (SES) differences in health. These are seen for most measures of SES, i e for education, occupation and income, and also for most health outcomes: for all-cause mortality, for morbidity in most diseases and for self-rated health. SES differences are, in particular, evident for coronary heart disease (CHD) with a two-fold difference in incidence and death between high and low SES groups. Causes for this are not clear. It is well known that an unhealthy lifestyle is more common in low SES but this can only explain a part of observed SES differences.
One possible explanation is effects of psychosocial factors. High levels of psychosocial risk factors and low availability of psychosocial resources are well documented predictors of CHD and more common in low SES. We and others have demonstrated that these factors are related to poor function of the HPA axis with reduced cortisol reactivity and with higher levels of markers for inflammation and plaque vulnerability, which also are known predictors of CHD.
The overall objective of the r
Research principal
Responsible department/unit
Department of Medical and Health Sciences
Ethics Review
Linköping - Ref. 02-324 and 2012/8031
Unit of analysis
Time Method
Sampling procedure
Time period(s) investigated
2003-09-30 – 2004-03-03
2012-08-21 – 2015-12-31
Biobank is connected to the study
Yes
Geographic spread
Geographic location: Sweden, Östergötland County, Jönköping County
Research area
HEALTH
(CESSDA Topic Classification)
Medical and Health Sciences
(The Swedish standard of fields of research 2011)
Access to data via
Homepage
Contact
Margareta Kristenson
Associated documentation
Description
Cohort 1: Data collection is conducted in collaboration with 10 Primary Health Care centers (PHCs) in Östergötland county council and sampling was done from the normal population of the catchment area for each PHC. The study is build on a comprehensive design with broad questionnaires on SES, psychosocial risk factors, psychological resources, lifestyle and present disease, anthropometrics, saliva and blood samples.Data format / data structure
Numeric
Creator/Principal investigator(s)
Margareta Kristenson - Linköping University, Department of Medical and Health Sciences
Number of individuals/objects
1007
Associated documentation
Description
Cohort 2: Data collection is conducted in collaboration with 27 PHCs in Östergötland and 19 PHCs in Jönköping county council. The same methods are used for collecting data, as described for cohort 1.Data format / data structure
Numeric
Creator/Principal investigator(s)
Margareta Kristenson - Linköping University, Department of Medical and Health Sciences
Number of individuals/objects
7051