Intergene - Living habits and health

This study is part of the collection Swedish Cohort Consortium (Cohorts.se) , Swedish Diet Cohort Consortium (SDCC)

Creator/Principal investigator(s):

Lauren Lissner - University of Gothenburg, Department of Public Health and Community Medicine

Annika Rosengren - University of Gothenburg, Department of Emergency and Cardiovascular Medicine

Dag Thelle

Kjell Torén - University of Gothenburg, Department of Public Health and Community Medicine

Description:

INTERGENE is a research program at the Sahlgrenska Academy, Universty of Gothenburg. The study is a collaboration between Department of community medicine and public health and Department of acute and cardiovascular medicine, Institution of Medicine.The background is that in spite of increasing insight in risk factors predisposing for coronary artery disease and improved treatment of those affected, the incidence of coronary heart disease is still high, even in younger age groups. The total disease risk expresses interaction between the gene frequency in a population, their lifestyle and the environment. The genetic mechanism can be due to either the increase in the classic risk factors, increased vulnerability for these factors and/or other genetic factors affecting the development of coronary heart disease.
Clinical data and data from questionnaires were collected in 2001-2004. The study is both a case-control study and a cross sectional study. The cases are consecutive patients with coronary heart disease, and consists of 623 patients from hospitals in Västra Götaland. The controls are thei

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Subject area:

HEALTH, specific diseases, disorders and medical conditions, general health and well-being, health behaviour (CESSDA Topic Classification)
Medical and Health Sciences (The Swedish standard of fields of research 2011)

Responsible department/unit:

University of Gothenburg, Department of Public Health and Community Medicine

Creator/Principal investigator(s):

Lauren Lissner - University of Gothenburg, Department of Public Health and Community Medicine

Annika Rosengren - University of Gothenburg, Department of Emergency and Cardiovascular Medicine

Dag Thelle

Kjell Torén - University of Gothenburg, Department of Public Health and Community Medicine

Identifiers:

SND-ID: SND 0014

Description:

INTERGENE is a research program at the Sahlgrenska Academy, Universty of Gothenburg. The study is a collaboration between Department of community medicine and public health and Department of acute and cardiovascular medicine, Institution of Medicine.The background is that in spite of increasing insight in risk factors predisposing for coronary artery disease and improved treatment of those affected, the incidence of coronary heart disease is still high, even in younger age groups. The total disease risk expresses interaction between the gene frequency in a population, their lifestyle and the environment. The genetic mechanism can be due to either the increase in the classic risk factors, increased vulnerability for these factors and/or other genetic factors affecting the development of coronary heart disease.
Clinical data and data from questionnaires were collected in 2001-2004. The study is both a case-control study and a cross sectional study. The cases are consecutive patients with coronary heart disease, and consists of 623 patients from hospitals in Västra Götaland. The controls are thei

... Show more..

Language:

Swedish

Time period(s) investigated:

2001-04-01 — 2004-12-01

2014 — 2016

Geographic spread:

Geographic location: Sweden

Lowest geographic unit:

Region

Unit of analysis:

Population:

Individuals aged 25-74 years and registered in Västra Götaland in april 2001

Subject area:

HEALTH, specific diseases, disorders and medical conditions, general health and well-being, health behaviour (CESSDA Topic Classification)
Medical and Health Sciences (The Swedish standard of fields of research 2011)

Contact for questions about the data:

Lauren Lissner

Is part of collection at SND:

Swedish Cohort Consortium (Cohorts.se)

Swedish Diet Cohort Consortium (SDCC)

Related research data in SND's catalogue:

Download metadata:

Publications

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Olin AC, Rosengren A, Thelle DS, Lissner L, Bake B, Toren K. Height, age, and atopy are associated with fraction of exhaled nitric oxide in a large adult general population sample. Chest 2006 Nov;130(5):1319-25.

Berg C, Rosengren A, Aires N, Lappas G, Toren K, Thelle D, Lissner L. Trends in overweight and obesity from 1985-2002 in Göteborg, West Sweden. Int J Obes 2005 Aug;29(8):916-24.

Berg C, Lappas G, Wolk A, Strandhagen E, Torén K, Rosengren A, Thelle D, Lissner L. Eating patterns and portion size associated with obesity in a Swedish population. Appetite 2008;52:21-6.

Berg C, Lissner L, Aires N, Lappas G, Toren K, Wilhelmsen L, Rosengren A, Thelle D. Trends in blood lipid levels, blood pressure, alcohol and smoking habits from 1985 to 2002: Results from INTERGENE and GOT-MONICA. Eur J Cardiovasc Prev Rehabil. 2005 Apr;12(2):115-25.

Hagg D, Englund MC, Jernas M, Schmidt C, Wiklund O, Hulten LM, Ohlsson BG, Carlsson LM, Carlsson B, Svensson PA. Oxidized LDL induces a coordinated up-regulation of the glutathione and thioredoxin systems in human macrophages. Atherosclerosis. 2006 Apr;185(2):282-9.

Strandhagen E, Berg C, Lissner L, Nunez L, Rosengren A, Torén K, Thelle DS. Selection bias in a population study with registry linkage - potential effect on social gradient in cardiovascular risk. Eur J Epidemiol. 2010 Mar;25(3):163-72
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Janson-Fagring A, Kjellgren K, Rosengren A, Lissner L, Manhem K, Welin C. Depression, anxiety, stress, social interaction and health-related quality of life in men and women with unexplained chest pain. BMC Public Health. 2008 May 19;8(1):165. [Epub ahead of print]

Wallentin Guron C, Hartford M, Rosengren A, Thelle D, Wallentin I, Caidahl K. Usefulness of atrial size inequality as an indicator of abnormal left ventricular filling. Am J Cardiol. 2005 Jun 15;95(12):1448-52.

Hagg D, Sjoberg S, Hulten LM, Fagerberg B, Wiklund O, Rosengren A, Carlsson LM, Boren J, Svensson PA, Krettek A. Augmented levels of CD44 in macrophages from atherosclerotic subjects: a possible IL-6-CD44 feedback loop? Atherosclerosis. 2007 Feb;190(2):291-7.

Olin AC, Bake B, Torén K. Fraction of exhaled nitric oxide at 50 mL/s: reference values for adult lifelong never-smokers. Chest 2008; 133: 831-832

Svensson PA, Englund MC, Snackestrand MS, Hagg DA, Ohlsson BG, Stemme V, Mattsson Hulten L, Thelle DS, Fagerberg B, Wiklund O, Carlsson LM, Carlsson B. Regulation and splicing of scavenger receptor class B type I in human macrophages and atherosclerotic plaques. BMC Cardiovasc Disord. 2005 Aug 25;5(1):25 [Epub ahead of print]

Berg J, Björck L, Dudas K, Lappas G, Rosengren A. Symptoms of a first acute myocardial infarction in women and men. Gend Med. 2009 Sep;6(3):454-62.

Wallentin Guron C, Bech-Hanssen O, Wikh R, Rosengren A, Hartford M, Caidahl K. The E/e filling index and right ventricular pressure in relation to applied international Doppler recommendations of left ventricular filling assessment. Eur J Echocardiogr. 2005 Dec;6(6):419-28.

Berg CM, Lappas G, Strandhagen E, Wolk A, Torén K, Rosengren A, Aires N, Thelle DS, Lissner L. Food patterns and cardiovascular disease risk factors: The Swedish INTERGENE research program. Am J Clin Nutr 2008; 88: 289-297.

Berggren U, Fahlke C, Aronsson E, Karanti A, Eriksson M, Blennow K, Thelle D, Zetterberg H, Balldin J. The taqI DRD2 A1 allele is associated with alcohol-dependence although its effect size is small. Alcohol Alcohol 2006 Sep-Oct;41(5):479-85. Epub 2006 Jun 2

The expression of NAD(P)H:Quinone Oxidoreductase 1 is high in human adipose tissue, reduced by weight loss, and correlates with adiposity, insulin sensitivity, and markers of liver dysfunction. J Clin Endocrinol Metab 2007; 92: 2346-2352

Hägg DA, Jernås M, Wiklund O, Thelle DS, Fagerberg B, Eriksson P, Hamsten A, Olsson B, Carlsson B, Carlsson LM, Svensson PA. Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes. Int J Mol Med. 2008 Jun;21(6):697-704.

Aminoff AK, Ledmyr H <http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=Search&Term=%22Ledmyr%20H%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus>, Thulin P, Lundell K, Nunez L, Strandhagen E, Murphy C, Lidberg U, Westerbacka J, Franco-Cereceda A, Liska J, Nielsen LB, Gåfvels M, Nastase Mannila M, Hamsten A, Yki-Järvinen H, Thelle D, Eriksson P, Borén J, Ehrenborg E. Allele-specific regulation of MTTP expression influences th

Berg C, Torén K, Rosengren A, Thelle DS, Lissner L, Olin A-C. Decreased exhaled nitric oxid (FENO) in obese with asthma symptoms: Data from the population study INTERGENE. Chest. 2010 Dec 23. [Epub ahead of print]

Hägg DA, Olson FJ, Kjelldahl J, Jernås M, Thelle DS, Carlsson LMS, Fagerberg B, Svensson PA. Expression of chemokine (C-C motif) ligand 18 in human macrophages and atherosclerotic plaques. Atherosclerosis 2009 Jun;204(2):e15-20.

Olin AC, Rosengren A, Thelle DS, Lissner L, Torén K. Increased fraction of exhaled nitric oxide predicts new-onset wheeze in a general population. Am J Respir Crit Care Med. 2010 Feb 15;181(4):324-7.

Jerlock M, Kjellgren KI, Gaston-Johansson F, Lissner L, Manhem K, Rosengren A, Welin C. Psychosocial profile in men and women with unexplained chest pain. A case-control study. J Intern Med 2008 Apr 4. [Epub ahead of print]

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Intergene - Living habits and health

Creator/Principal investigator(s):

Lauren Lissner - University of Gothenburg, Department of Public Health and Community Medicine

Annika Rosengren - University of Gothenburg, Department of Emergency and Cardiovascular Medicine

Dag Thelle

Kjell Torén - University of Gothenburg, Department of Public Health and Community Medicine

Data format / data structure:

Numeric

Data collection:

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2001 — 2004

Source of the data: Population group, Biological samples

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2001 — 2004

Source of the data: Population group, Biological samples

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2014 — 2016

Source of the data: Population group, Biological samples

Mode of collection: Physical measurements and tests

Time period(s) for data collection: 2014 — 2016

Source of the data: Population group, Biological samples

Variables:

600

Number of individuals/objects:

4634

Response rate/participation rate:

43%

Published: 2011-01-01
Last updated: 2017-06-26