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Association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis

SND-ID: SND 1082

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Description

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Language

English

Research principal, contributors, and funding

Research principal

University of Gothenburg

Responsible department/unit

University of Gothenburg, Department of internal medicine and clinical nutrition
Protection and ethical review

Ethics Review

Gothenburg - Ref. 731-09

Method and time period

Unit of analysis

Population

IBS and healthy controls; gut microbiota-brain-symptom interactions

Time Method

Sampling procedure

Other
Clinical sample of IBS patients; healthy volunteers
Geographic coverage

Geographic spread

Geographic location: Sweden

Topic and keywords

Research area

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology (The Swedish standard of fields of research 2011)
Health (INSPIRE topic categories)

Keywords

irritable bowel syndrome, gut microbiota

Publications

Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis. Microbiome 7, 45 (2019) doi:10.1186/s40168-019-0656-z
Link to article
DOI: https://doi.org/10.1186/s40168-019-0656-z

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Dataset
Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis

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Version 1.0

Citation

Magnus Simrén. University of Gothenburg, Department of internal medicine and clinical nutrition (2019). Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis. Swedish National Data Service. Version 1.0. https://doi.org/10.5878/ejpj-p674

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Data format / data structure

Numeric

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Time period(s) investigated

2010 – 2015

Published: 2019-02-06
Last updated: 2019-12-10