Association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis

Creator/Principal investigator(s):

Magnus Simren - University of Gothenburg

Description:

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Subject area:

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology (The Swedish standard of fields of research 2011)
Health (INSPIRE topic categories)

Keywords:

Irritable Bowel Syndrome, gut microbiota

Principal organisation:

University of Gothenburg

Accessibility status:

Access to data through SND
Data are freely accessible

Download data:

SND1082-001-V1.0.zip (609.75 KB)

Responsible department/unit:

Creator/Principal investigator(s):

Magnus Simren - University of Gothenburg

Identifiers:

SND-ID: SND 1082

Description:

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Language:

English

Geographic spread:

Geographic location: Sweden

Unit of analysis:

Population:

IBS and healthy controls; gut microbiota-brain-symptom interactions

Time Method:

Sampling procedure:

Other
Clinical sample of IBS patients; healthy volunteers

Ethics Review:

Gothenburg —731-09

Subject area:

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology (The Swedish standard of fields of research 2011)
Health (INSPIRE topic categories)

Keywords:

Irritable Bowel Syndrome, gut microbiota

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Publications

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Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis. Microbiome 7, 45 (2019) doi:10.1186/s40168-019-0656-z
Link to article

If you have published anything based on these data, please notify us with a reference to your publication(s).

Version 1.0:

2019-02-05 doi:10.5878/ejpj-p674

Download data:

SND1082-001-V1.0.zip (609.75 KB)

Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis

Citation:

Magnus Simren. University of Gothenburg, Department of internal medicine and clinical nutrition (2019). Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis. Swedish National Data Service. Version 1.0. https://doi.org/10.5878/ejpj-p674

Data format / data structure:

Numeric

Time period(s) investigated:

2010 — 2015