Association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Description

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Subject area

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology (The Swedish standard of fields of research 2011)
Health (INSPIRE topic categories)

Keywords

irritable bowel syndrome, gut microbiota

Principal organisation

University of Gothenburg

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SND1082-001-V1.0.zip (609.75 KB)

Responsible department/unit

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Identifiers

SND-ID: SND 1082

Description

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Language

English

Geographic spread

Geographic location: Sweden

Unit of analysis

Population

IBS and healthy controls; gut microbiota-brain-symptom interactions

Time Method

Sampling procedure

Other
Clinical sample of IBS patients; healthy volunteers

Ethics Review

Gothenburg — Ref. 731-09

Subject area

HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology (The Swedish standard of fields of research 2011)
Health (INSPIRE topic categories)

Keywords

irritable bowel syndrome, gut microbiota

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Publications

Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis. Microbiome 7, 45 (2019) doi:10.1186/s40168-019-0656-z
Link to article
DOI: https://doi.org/10.1186/s40168-019-0656-z

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Version 1.0

2019-02-05
https://doi.org/10.5878/ejpj-p674

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Download data

SND1082-001-V1.0.zip (609.75 KB)

Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis

Citation

Magnus Simrén. University of Gothenburg, Department of internal medicine and clinical nutrition (2019). <em>Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis</em>. Swedish National Data Service. Version 1.0. <a href="https://doi.org/10.5878/ejpj-p674">https://doi.org/10.5878/ejpj-p674</a>

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Data format / data structure

Numeric

Time period(s) investigated

2010 — 2015

Published: 2019-02-06
Last updated: 2019-12-10