Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

Creator/Principal investigator(s):

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Description:

Background: The risk of infection after transrectal ultrasound (TRUS)-guided prostate biopsies is increasing. The aim of the study was to assess the use of antibiotic prophylaxis for prostate biopsy in Sweden.

Methods: All public and private urology clinics reporting to the National Prostate Cancer Register of Sweden received a survey on TRUS-biopsy prophylaxis.

Results: Of the 84 clinics surveyed, 76 replied (90%). If no risk factors for infection were present, a single dose of ciprofloxacin 750 mg was used by 50 clinics (66%). Multiple doses of ciprofloxacin 500 or 750 mg (n=14; 18%) or a single dose of trimethoprim-sulfamethoxazole 160/800 mg (n=7; 9%) were other common prophylaxes. Most clinics gave the prophylaxes immediately before the biopsy (n=41; 54%). Urine dipstick was used by 30 clinics (39%) and rectal enema by six (8%). In patients with high risk of infection, the survey mirrors a large variety of regiments used.

Conclusions: The preference to use a single dose of ciprofloxacin 750 mg is in accordance with the Swedish national guidelines for patients with a low risk of infec

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Principal organisation:

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Responsible department/unit:

Umeå University, Department of Surgical and Perioperative Sciences

Creator/Principal investigator(s):

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Contributor(s):

Sven Resare - Umeå University, Department of Surgical and Perioperative Sciences

Karl-Johan Lundström - Umeå University, Department of Surgical and Perioperative Sciences

Christofer Lagerros - Umeå University, Department of Surgical and Perioperative Sciences

Pär Stattin - Umeå University, Department of Surgical and Perioperative Sciences orcid

Identifiers:

SND-ID: SND 1137

Description:

Background: The risk of infection after transrectal ultrasound (TRUS)-guided prostate biopsies is increasing. The aim of the study was to assess the use of antibiotic prophylaxis for prostate biopsy in Sweden.

Methods: All public and private urology clinics reporting to the National Prostate Cancer Register of Sweden received a survey on TRUS-biopsy prophylaxis.

Results: Of the 84 clinics surveyed, 76 replied (90%). If no risk factors for infection were present, a single dose of ciprofloxacin 750 mg was used by 50 clinics (66%). Multiple doses of ciprofloxacin 500 or 750 mg (n=14; 18%) or a single dose of trimethoprim-sulfamethoxazole 160/800 mg (n=7; 9%) were other common prophylaxes. Most clinics gave the prophylaxes immediately before the biopsy (n=41; 54%). Urine dipstick was used by 30 clinics (39%) and rectal enema by six (8%). In patients with high risk of infection, the survey mirrors a large variety of regiments used.

Conclusions: The preference to use a single dose of ciprofloxacin 750 mg is in accordance with the Swedish national guidelines for patients with a low risk of infec

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Language:

English

Time period(s) investigated:

2006-01-01 — 2014-12-31

Geographic spread:

Geographic location: Sweden

Lowest geographic unit:

Region

Highest geographic unit:

Country

Unit of analysis:

Population:

No patient data are reported. All clinics reporting to the National prostate cancer register answered questions on clinic routines.

Study design:

Observational study

Description of study design:

Survey

Sampling procedure:

Total universe/Complete enumeration

Ethics Review:

Umeå — Ref. 2016/228-31

Funding:

Region Västernorrland

National Prostate Cancer Register (NPCR) of Sweden

Version 1.0:

Download data:

License:

CC0

Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

Suggested citation:

Johan Styrke. Umeå University, Department of Surgical and Perioperative Sciences (2020). Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden. Swedish National Data Service. Version 1.0. https://doi.org/10.5878/zdne-z984

Creator/Principal investigator(s):

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Description:

Survey data methodology
Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

An electronic survey was distributed to all of the hospitals and outpatient urology clinics reporting to the national Swedish National Prostate Cancer Register (NPCR). The web-based Information Network for CAncer registers in Sweden (INCA) platform was used for reporting. Recipients of the survey were the trained staff reporting to the NPC

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Data format / data structure:

Numeric

Text

Data collection:

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2014-11-26 — 2015-11-03

Source of the data: Communications: Interpersonal, Forskningsdata: Opublicerade

Time period(s) investigated:

2006-01-01 — 2014-12-31

Variables:

27

Published: 2020-01-21