Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

Creator/Principal investigator(s)

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Description

Background: The risk of infection after transrectal ultrasound (TRUS)-guided prostate biopsies is increasing. The aim of the study was to assess the use of antibiotic prophylaxis for prostate biopsy in Sweden.

Methods: All public and private urology clinics reporting to the National Prostate Cancer Register of Sweden received a survey on TRUS-biopsy prophylaxis.

Results: Of the 84 clinics surveyed, 76 replied (90%). If no risk factors for infection were present, a single dose of ciprofloxacin 750 mg was used by 50 clinics (66%). Multiple doses of ciprofloxacin 500 or 750 mg (n=14; 18%) or a single dose of trimethoprim-sulfamethoxazole 160/800 mg (n=7; 9%) were other common prophylaxes. Most clinics gave the prophylaxes immediately before the biopsy (n=41; 54%). Urine dipstick was used by 30 clinics (39%) and rectal enema by six (8%). In patients with high risk of infection, the survey mirrors a large variety of regiments used.

Conclusions: The preference to use a single dose of ciprofloxacin 750 mg is in accordance with the Swedish national guidelines for patients with a low risk of infec

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Principal organisation

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Creator/Principal investigator(s)

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Contributor(s)

Karl-Johan Lundström - Umeå University, Department of Surgical and Perioperative Sciences

Christofer Lagerros - Umeå University, Department of Surgical and Perioperative Sciences

Sven Resare - Umeå University, Department of Surgical and Perioperative Sciences

Pär Stattin - Umeå University, Department of Surgical and Perioperative Sciences orcid

Identifiers

SND-ID: SND 1137

Description

Background: The risk of infection after transrectal ultrasound (TRUS)-guided prostate biopsies is increasing. The aim of the study was to assess the use of antibiotic prophylaxis for prostate biopsy in Sweden.

Methods: All public and private urology clinics reporting to the National Prostate Cancer Register of Sweden received a survey on TRUS-biopsy prophylaxis.

Results: Of the 84 clinics surveyed, 76 replied (90%). If no risk factors for infection were present, a single dose of ciprofloxacin 750 mg was used by 50 clinics (66%). Multiple doses of ciprofloxacin 500 or 750 mg (n=14; 18%) or a single dose of trimethoprim-sulfamethoxazole 160/800 mg (n=7; 9%) were other common prophylaxes. Most clinics gave the prophylaxes immediately before the biopsy (n=41; 54%). Urine dipstick was used by 30 clinics (39%) and rectal enema by six (8%). In patients with high risk of infection, the survey mirrors a large variety of regiments used.

Conclusions: The preference to use a single dose of ciprofloxacin 750 mg is in accordance with the Swedish national guidelines for patients with a low risk of infec

... Show more..

Language

English

Time period(s) investigated

2006-01-01 — 2014-12-31

Geographic spread

Geographic location: Sweden

Lowest geographic unit

Region

Highest geographic unit

Country

Population

No patient data are reported. All clinics reporting to the National prostate cancer register answered questions on clinic routines.

Study design

Observational study

Description of study design

Survey

Sampling procedure

Total universe/Complete enumeration
The survey was sent to al clinics reporting to the National prostate cancer register.

Ethics Review

Umeå — Ref. 2016/228-31

Funding

Funding agency: Region Västernorrland

Funding agency: National Prostate Cancer Register (NPCR) of Sweden

Version 1.0

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Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

Citation

Johan Styrke. Umeå University, Department of Surgical and Perioperative Sciences (2020). <em>Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden</em>. Swedish National Data Service. Version 1.0. <a href="https://doi.org/10.5878/zdne-z984">https://doi.org/10.5878/zdne-z984</a>

Creator/Principal investigator(s)

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Description

Survey data methodology
Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

An electronic survey was distributed to all of the hospitals and outpatient urology clinics reporting to the national Swedish National Prostate Cancer Register (NPCR). The web-based Information Network for CAncer registers in Sweden (INCA) platform was used for reporting. Recipients of the survey were the trained staff reporting to the NPC

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Data format / data structure

Numeric

Text

Data collection

Mode of collection: Self-administered questionnaire

Time period(s) for data collection: 2014-11-26 — 2015-11-03

Source of the data: Communications: Interpersonal, Forskningsdata: Opublicerade

Time period(s) investigated

2006-01-01 — 2014-12-31

Variables

27

Published: 2020-01-21