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Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

SND-ID: SND 1137

Creator/Principal investigator(s)

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Description

Background: The risk of infection after transrectal ultrasound (TRUS)-guided prostate biopsies is increasing. The aim of the study was to assess the use of antibiotic prophylaxis for prostate biopsy in Sweden.

Methods: All public and private urology clinics reporting to the National Prostate Cancer Register of Sweden received a survey on TRUS-biopsy prophylaxis.

Results: Of the 84 clinics surveyed, 76 replied (90%). If no risk factors for infection were present, a single dose of ciprofloxacin 750 mg was used by 50 clinics (66%). Multiple doses of ciprofloxacin 500 or 750 mg (n=14; 18%) or a single dose of trimethoprim-sulfamethoxazole 160/800 mg (n=7; 9%) were other common prophylaxes. Most clinics gave the prophylaxes immediately before the biopsy (n=41; 54%). Urine dipstick was used by 30 clinics (39%) and rectal enema by six (8%). In patients with high risk of infection, the survey mirrors a large variety of regiments used.

Conclusions: The preference to use a single dose of ciprofloxacin 750 mg is in accordance with the Swedish national guidelines for patients with a low risk of infec

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Language

English

Research principal, contributors, and funding

Research principal

Umeå University

Responsible department/unit

Department of Surgical and Perioperative Sciences

Contributor(s)

Karl-Johan Lundström - Umeå University, Department of Surgical and Perioperative Sciences

Christofer Lagerros - Umeå University, Department of Surgical and Perioperative Sciences

Sven Resare - Umeå University, Department of Surgical and Perioperative Sciences

Pär Stattin - Umeå University, Department of Surgical and Perioperative Sciences orcid

Funding 1

  • Funding agency: Region Västernorrland

Funding 2

  • Funding agency: National Prostate Cancer Register (NPCR) of Sweden
Protection and ethical review

Ethics Review

Umeå - Ref. 2016/228-31

Method and time period

Unit of analysis

Population

No patient data are reported. All clinics reporting to the National prostate cancer register answered questions on clinic routines.

Study design

Observational study

Description of study design

Survey

Sampling procedure

Total universe/Complete enumeration
The survey was sent to al clinics reporting to the National prostate cancer register.

Time period(s) investigated

2006-01-01 – 2014-12-31

Geographic coverage

Geographic spread

Geographic location: Sweden

Lowest geographic unit

Region

Highest geographic unit

Country

Topic and keywords

Research area

Urology and Nephrology (The Swedish standard of fields of research 2011)

Keywords

antibiotic prophylaxis, survey, prostate biopsy, prostate cancer diagnosis

Publications
Dataset
Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

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Description

Survey data methodology
Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden

An electronic survey was distributed to all of the hospitals and outpatient urology clinics reporting to the national Swedish National Prostate Cancer Register (NPCR). The web-based Information Network for CAncer registers in Sweden (INCA) platform was used for reporting. Recipients of the survey were the trained staff reporting to the NPC

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Version 1.0

Citation

Johan Styrke. Umeå University (2020). Current routines for antibiotic prophylaxis prior to transrectal prostate biopsy – a national survey to all urology clinics in Sweden. Swedish National Data Service. Version 1.0. https://doi.org/10.5878/zdne-z984

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Data format / data structure

Numeric

Text

Creator/Principal investigator(s)

Johan Styrke - Umeå University, Department of Surgical and Perioperative Sciences

Time period(s) investigated

2006-01-01 – 2014-12-31

Data collection

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2014-11-26–2015-11-03
  • Source of the data: Communications: Interpersonal, Research data: Unpublished

Variables

27

License

Creative Commons Public Domain Dedication (CC0 1.0)

Published: 2020-01-21