Creator/Principal investigator(s)
Olav Rooyackers - Karolinska Institutet
Martin Sundström Rehal
- Karolinska Institutet
Description
Patients with EN >80% of energy target as determined by indirect calorimetry were randomized to or 50% or 100% of current EN rate. After 24 hours, whole body protein kinetics were determined by enteral and parenteral stable isotope tracer infusions. Treatment allocation was then switched, and tracer investigations repeated 24 hours later in a crossover design with patients serving as their own controls.
Language
English
Research principal
Responsible department/unit
Anesthesiology and Intensive Care/CLINTEC
Contributor(s)
Felix Liebau - Karolinska Institutet
Jan Wernerman - Karolinska Institutet
Data contains personal data
No
Ethics Review
Stockholm - Ref. 2016/76-31/4
Population
Adult ICU patients with invasive mechanical ventilation and an FiO2 of =/<0.6.
Study design
Experimental study
Time period(s) investigated
2016-12-14 – 2018-03-05
Biobank is connected to the study
Yes
Geographic spread
Geographic location: Stockholm County
Download data
Description
The files give all data for calculating whole body protein kinetics and the amino acids and urea concentrations at the end of the two 24h intervention periods (day 1 and day 2).
The file "Tracer infusions" gives the details of the preparation of the tracers infused during the two days, including the volumes taken up in the syringes, the dilutions and the final weight of the syringes. All this information is used to calculate the exact rates of infusion in micromol per kg bodyweight per hour.
Version 1
https://doi.org/10.5878/b1e8-fg58
Citation
Download citation
Data format / data structure
Numeric
Creator/Principal investigator(s)
Olav Rooyackers - Karolinska Institutet
Martin Sundström Rehal
- Karolinska Institutet