Collection: SIMPLER - Swedish Infrastructure for Medical Population-Based Life-Course and Environmental Research

Responsible department/unit:

Uppsala University

Description:

SIMPLER is an indvidual-based database and biobank primarily for epidemiological research. The database consists of two population-based cohorts, Swedish Mammography Cohort and Cohort of Swedish Men, and covers a total of approximately 110 000 persons born 1914–1952, from the counties of Uppsala, Västmanland and Örebro. Data collection from the participants has been made continuously since 1987, through regular mailings of questionnaires and surveys, as well as linking to register-based data. A biobank with DNA and other biological samples from a large number of the participants is available.

Data and samples from SIMPLER are used for research into areas such as cancer, neurological disease, circulatory disease, digestive system disease, kidney disease, diabetes and osteoporosis.

The SIMPLER consortium is coordinated by Uppsala University, with participation by Chalmers University of Technology, Karolinska Institutet and Örebro University.

Director is Karl Michaëlsson, Uppsala universitet.

Kind of collection:

Research infrastructure

Subject area:

specific diseases, disorders and medical conditions, HEALTH (CESSDA Topic Classification)
Medical and Health Sciences, Cancer and Oncology, Clinical Medicine, Endocrinology and Diabetes, Cardiac and Cardiovascular Systems (The Swedish standard of fields of research 2011)

Keywords:

Geographic location:

Sweden

Publications

Andersson SO, Rashidkhani B, Karlberg L, Wolk A, Johansson JE. Prevalence of Lower urinary tract symptoms in men aged 45-79 years - A population-based study of 40,000 Swedish men. Brit J Urol 2004;94:327-331

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.

Kaluza J, Håkansson N, Brzozowska A, Wolk A. Diet quality and mortality: a population-based prospective study of men. European Journal of Clinical Nutrition (2009); 63:451-457

Larsson SC, Wolk K, Brismar K, Wolk A. Association of diet with serum insulin-like growth factor-I in middle-aged and elderly men. Am J Clin Nutr 2005; 81:1163-67.

Stackelberg O, Björck M, Larsson SC, Orsini N, Wolk A. Fruit and vegetable consumption with risk of abdominal aortic aneurysm. Circulation 128(8):795-802, 2013.

Wolk A, Larsson SC, Johansson JE, Ekman P. Long-term fatty fish consumption and renal cell carcinoma incidence in women. JAMA. 296(11):1371-6, 2006.

Åkesson A, Larsson SC, Discacciati A, Wolk A. Low-Risk Dietary and Lifestyle Practices in Primary Prevention of Myocardial Infarction in Men. J Am Coll Cardiol 64(13):1299-306, 2014.

Homepage:

SIMPLER

Related data in SND's catalogue:

The Cohort of Swedish Men, COSM

The Swedish Mammography Cohort, SMC

Related collections in SND's catalogue:

Swedish Cohort Consortium (Cohorts.se)