Creator/Principal investigator(s)
Gustav Nilsonne, KI
- Karolinska Institutet, Department of Clinical Neuroscience
Sandra Tamm
- Karolinska Institutet, Department of Clinical Neuroscience
Paolo d'Onofrio - Stockholm University, Stress Research Institute
Hanna Thuné - Stockholm University, Stress Research Institute
Johanna Schwarz
- Stockholm University, Department of Psychology
Description
The Stockholm Sleepy Brain Study I is a functional brain imaging study of 48 younger (20-30 years) and 36 older (65-75 years) healthy participants, with magnetic resonance imaging after normal sleep and partial sleep deprivation in a crossover design. We performed experiments investigating emotional mimicry, empathy for pain, and cognitive reappraisal, as well as resting state functional magnetic resonance imaging (fMRI). We also acquired T1- and T2-weighted structural images and diffusion tensor images (DTI). On the night before imaging, participants were monitored with ambulatory polysomnography and were instructed to sleep either as usual or only three hours. Participants came to the scanner the following evening. Besides MRI scanning, participants underwent behavioral tests and contributed blood samples, which have been stored in a biobank and used for DNA analyses. Participants also completed a variety of self-report measures. The resulting multimodal dataset may be useful for hypothesis generation or independent validation of effects of sleep deprivation and aging, as well as investigati
... Show more..Language
English
Research principal
Responsible department/unit
Department of Clinical Neuroscience
Contributor(s)
Stockholm University, Stress Research Institute
Funding 1
-
Funding agency:
Fredrik and Ingrid Thuring Foundation
- Funding agency's reference number: 2014-00037, 2015-00170
Funding 2
-
Funding agency:
Riksbankens Jubileumsfond
- Funding agency's reference number: P15-0310:1
Data contains personal data
No
Ethics Review
Stockholm - Ref. 2012/1098-31/2
Unit of analysis
Population
Healthy volunteers
Study design
Double-blind randomised trial
Time period(s) investigated
2012-12-04 – 2013-03-27
2013-10-24 – 2014-04-29
Biobank is connected to the study
Yes
Åkerstedt T, Lekander M, Nilsonne G, Tamm S, d’Onofrio P, Kecklund G, Fischer H, Schwarz J, Petrovic P, Månsson KNT. Gray matter volume correlates of sleepiness: a voxel–based morphometry study in younger and older adults. Nature and Science of Sleep 2020, 12, 289-198.
DOI:
https://doi.org/10.2147/NSS.S240493
Nilsonne G, Tamm S, d’Onofrio P, Thuné HÅ, Schwarz J, Lavebratt C, Liu, JJ, Månsson KNT, Sundelin T, Axelsson J, Fransson P, Kecklund G, Fischer H, Lekander M, Åkerstedt Torbjörn. A multimodal brain imaging dataset on sleep deprivation in young and old humans. Karolinska Open Archive. url: http://hdl.handle.net/10616/45181
Handle:
10616/45181
Koba C, Notaro G, Tamm S, Nilsonne G, Hasson U. Spontaneous eye-movements during eyes-open rest reduce resting-state-network modularity by increasing visual-sensorimotor connectivity. bioRχiv. doi: 10.1101/2020.05.18.100669
DOI:
https://doi.org/10.1101/2020.05.18.100669
Åkerstedt T, Lekander M, Nilsonne G, Tamm S, d’Onofrio P, Kecklund G, Fischer H, Schwarz J. Effects of late night short sleep on in-home polysomnography – relation to adult age and sex. Journal of Sleep Research 2017. doi: 10.1111/jsr.12626
DOI:
https://doi.org/10.1111/jsr.12626
Tamm S, Nilsonne G, Lamm C, Kecklund G, Petrovic P, Fischer H, Åkerstedt T, Lekander M. The effect of sleep restriction on empathy for pain: An fMRI study in younger and older adults. Scientific Reports 2017 7:12236. doi: 10.1038/s41598-017-12098-9
DOI:
https://doi.org/10.1038/s41598-017-12098-9
Tamm S, Nilsonne G, Schwarz J, Golkar A, Kecklund G, Petrovic P, Fischer H, Åkerstedt T, Lekander M. Sleep restriction caused impaired emotional regulation without detectable brain activation changes – a functional magnetic resonance imaging study. Royal Society Open Science, 6(3), 181704. doi: 10.1098/rsos.181704
DOI:
https://doi.org/10.1098/rsos.181704
Nilsonne G, Tamm S, Schwarz J, Almeida R, Fischer H, Kecklund G, Lekander M, Fransson P, Åkerstedt T. Intrinsic brain connectivity after partial sleep deprivation in young and older adults: results from the Stockholm Sleepy Brain Study. Scientific Reports 2017 7:9422. doi: 10.1038/s41598-017-09744-7
DOI:
https://doi.org/10.1038/s41598-017-09744-7
If you have published anything based on these data, please notify us with a reference to your publication(s). If you are responsible for the catalogue entry, you can update the metadata/data description in DORIS.
Associated documentation
Description
The dataset is available for download with the tool Datalad (https://www.datalad.org/). The command after installing Datalad is:datalad install -r https://github.com/NilsonneData/SleepyBrain1.git
Earlier versions of this dataset can be found here: https://openneuro.org/datasets/ds000201/versions/1.0.3
Version 1
https://doi.org/10.5878/87y5-kh22
Citation
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Data format / data structure
Numeric
Text
Other
Creator/Principal investigator(s)
Gustav Nilsonne, KI
- Karolinska Institutet, Department of Clinical Neuroscience
Keywords
emotions, electromyography, magnetic resonance imaging, sleep deprivation, polysomnography, expressed emotion, diffusion tensor imaging
Number of individuals/objects
90