• A landscape of X-inactivation during human T-cell development in the thymus

The aim of the study was to investigate X-inactivation during human T-cell development in the thymus. Thymocytes from six different developmental stages from seven individuals were isolated and studied regarding gene exp...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Immunocytofluoroscense of Hsp70-mutant yeast strains with primary antibodies against Hsp42p

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Western blots of SDS-PAGE gels with primary antibodies against Hsp70p and Pgk1p

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - The molecular chaperone GFP-Hsp104 before and after heat stress in Hsp70-mutant yeast strains

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Silver stained 2D-gels of protein extracts from wild type and Hsp70-mutant yeast strains

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Timelapse microscopy of the misfolding protein guk1-7-GFP in recovery after heat stress in Hsp70- and Hsp104-mutant yeast strains

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Intracellular colocalisation of the chaperone Ssa4-GFP and the metacaspase Mca1-RFP before and after heat stress in a Hsp70-mutant yeast cell strain

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - The misfolding protein marker guk1-7-GFP before, during and after in recovery from heat shock stress in Hsp70-mutant yeast strains

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - The misfolding protein marker gus1-3-GFP and the metacaspase Mca1-GFP during mid-exponential growth in yeast Hsp70-mutant yeast strains

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...

• Study of the yeast cytosolic Hsp70-system in protein homeostasis and life span regulation - Hsp70-mutant yeast strains with the misfolding marker protein guk1-7-GFP and with or without an intact HSP104-allele, imaged during mid-exponential growth

Our study aims to answer the question "Which functions of the Hsp70 class of molecular chaperones are essential for yeast to maintain a standard replicative life span?". To answer this question, we utilised the disparate...